Research library: browse by date
The Research Library categorizes and provides access to all recent glycobiology-related research published by Nature Publishing Group and other journals. The selection is deliberately broad to facilitate access to all research impacting on the glycobiology community. Both primary research and review articles are included.
November 2006
Characterization of Helicobacter pylori Lytic Transglycosylases Slt and MltD
C. Chaput, A. Labigne and I. G. Boneca
Original research paper: Journal of Bacteriology 189
doi:10.1128/JB.01270-06Cloning of a Cholesterol- -glucosyltransferase from Helicobacter pylori
A.-H. Lebrun
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M603345200Understanding the Biological Rationale for the Diversity of Cellulose-directed Carbohydrate-binding Modules in Prokaryotic Enzymes
A. W. Blake
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605903200Cj1121c, a Novel UDP-4-keto-6-deoxy-GlcNAc C-4 Aminotransferase Essential for Protein Glycosylation and Virulence in Campylobacter jejuni
S. Vijayakumar
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M511714200The Structure of the Major Cell Wall Polysaccharide of Bacillus anthracis Is Species-specific
B. Choudhury
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605768200The herpesvirus glycoproteins B and H{middle dot}L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry
T. Gianni
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0606127103The love–hate relationship between bacterial polysaccharides and the host immune system
Sarkis K. Mazmanian and Dennis L. Kasper
Original research paper: Nature Reviews Immunology 6 849-858 (2006)
doi:10.1038/nri1956Targeting of CD44 eradicates human acute myeloid leukemic stem cells
Liqing Jin et al.
Original research paper: Nature Medicine 12 1167-1174 (2006)
doi:10.1038/nm1483Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat
M. A. Tarp et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl061Effect of membrane-bound IgG and desialysation in the interaction of monocytes with senescent erythrocytes
A. Ensinck et al.
Original research paper: Clinical and Experimental Medicine 6
doi:10.1007/s10238-006-0110-yComplement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells
María Jesús Martín, Alysson Muotri, Fred H. Gage and Ajit Varki
Original research paper: Nature Medicine 12 1115
doi:10.1038/nm1006-1115Complement targeting of nonhuman sialic acid does not mediate cell death of human embryonic stem cells
Chantal Cerdan et al.
Original research paper: Nature Medicine 12 1113-1114
doi:10.1038/nm1006-1113An N-Linked Glycan Modulates the Interaction between the CD1d Heavy Chain and beta2-Microglobulin
C. Paduraru et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M608518200Multiple Antigenic Mimotopes of HIV Carbohydrate Antigens: Relating Structure and Antigenicity
A. D. Pashov
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604137200Monocyte Differentiation Up-regulates the Expression of the Lysosomal Sialidase, Neu1, and Triggers Its Targeting to the Plasma Membrane via Major Histocompatibility Complex Class II-positive Compartments
F. Liang
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605633200Galactosylation of IgG from rheumatoid arthritis (RA) patients – changes during therapy
Marta Pasek et al.
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-5409-0Molecular mechanisms of muscular dystrophies: old and new players
Kay E Davies and Kristen J Nowak
Original research paper: Nature Reviews Molecular Cell Biology 7 762-773 (2006)
doi:10.1038/nrm2024Inhibition of influenza-virus-induced cytopathy by sialylglycoconjugates
T Terabayashi et al.
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.017Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor
W. Cai
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0600362103Structure and function relations with a T-cell-activating polysaccharide antigen using circular dichroism
L. S.C. Kreisman, J. H. Friedman, A. Neaga and B. A. Cobb
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl056Monitoring of heparin and its low-molecular-weight analogs by silicon field effect
N. M. Milovic
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0604471103Sweetening up yeast glycoprotein synthesis
Allison Doerr
Original research paper: Nature Methods 3 874
doi:10.1038/nmeth1106-874bUsing substrate engineering to harness enzymatic promiscuity and expand biological catalysis
Luke L Lairson, Andrew G Watts, Warren W Wakarchuk and Stephen G Withers
Original research paper: Nature Chemical Biology 2 724-728 (2006)
doi:10.1038/nchembio828N-Glycan structures and N-glycosylation sites of mouse soluble intercellular adhesion molecule-1 revealed by MALDI-TOF and FTICR mass spectrometry
V. I. Otto
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl032Synthesis of new analogues of salacinol containing a pendant hydroxymethyl group as potential glycosidase inhibitors
R Nasi and B Pinto
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.022A facile synthesis of 1,6-dideoxynojirimycin from l-sorbose
J An, X Meng, Y Yao and Z Li
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.002A Novel -Helix in the First Fibronectin Type III Repeat of the Neural Cell Adhesion Molecule Is Critical for N-Glycan Polysialylation
S. S. Mendiratta et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M608073200Spacer-separated sialyl LewisX cyclopeptide conjugates as potential E-selectin ligands
H Herzner and H Kunz
Original research paper: Carbohydrate Research
doi:10.1016/j.carres.2006.09.012Human complement factor I glycosylation: Structural and functional characterisation of the N-linked oligosaccharides
S Tsiftsoglou et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics 1764
doi:10.1016/j.bbapap.2006.09.007Why does avian influenza A virus hemagglutinin bind to avian receptor stronger than to human receptor? Ab initio fragment molecular orbital studies
T Sawada et al.
Original research paper: Biochemical and Biophysical Research Communications 351
doi:10.1016/j.bbrc.2006.09.165Identification of the Sialic Acid Structures Recognized by Minute Virus of Mice and the Role of Binding Affinity in Virulence Adaptation
H.-J. Nam
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604421200Structure of the Epstein-Barr virus major envelope glycoprotein
Gerda Szakonyi et al.
Original research paper: Nature Structural & Molecular Biology 13 996-1001 (2006)
doi:10.1038/nsmb1161Structural insights into the Notch-modifying glycosyltransferase Fringe
Martin Jinek et al.
Original research paper: Nature Structural & Molecular Biology 13 945-946 (2006)
doi:10.1038/nsmb1144Structural elucidation of the O-antigenic polysaccharide from enterohemorrhagic (EHEC) Escherichia coli O48:H21
L Maclean, A Webb and M Perry
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.08.008Synthesis of novel σ-receptor ligands from methyl α-d-mannopyranoside
K Wiedemeyer and B Wunsch
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.06.016Physicochemical properties and antitumor activities of water-soluble native and sulfated hyperbranched mushroom polysaccharides
Y Tao, L Zhang and P Cheung
Original research paper: Carbohydrate Research 341
doi:10.1016/j.carres.2006.05.024Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy
H. Kogelberg et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl053Cyanovirin-N Inhibits Hepatitis C Virus Entry by Binding to Envelope Protein Glycans
F. Helle
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M602431200A sugar switch for anti-inflammatory antibodies
Roy Jefferis
Original research paper: Nature Biotechnology 24 1230-1231
doi:10.1038/nbt1006-1230Sulfated L-selectin ligands as a therapeutic target in chronic inflammation
K Uchimura and S Rosen
Original research paper: Trends in Immunology 27
doi:10.1016/j.it.2006.10.007Detection of oligosaccharide ligands for Hepatocyte growth factor/Scatter factor (HGF/SF), Keratinocyte growth factor (KGF/FGF-7), RANTES and Heparin cofactor II by neoglycolipid microarrays of glycosaminoglycan-derived oligosaccharide fragments
Keiko Yamaguchi, Hirotoshi Tamaki and Shigeyuki Fukui
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-7151-zN-Glycosylation of Fibroblast Growth Factor Receptor 1 Regulates Ligand and Heparan Sulfate Co-receptor Binding
L. Duchesne
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M601248200Sweet deception
Shannon Amoils
Original research paper: Nature Reviews Microbiology 4 802-803
doi:10.1038/nrmicro1545Neural Cell Adhesion Molecule-associated Polysialic Acid Inhibits NR2B-containing N-Methyl-D-aspartate Receptors and Prevents Glutamate-induced Cell Death
M. S. L. Hammond et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M602568200N-Glycosylation of the beta-Propeller Domain of the Integrin 5 Subunit Is Essential for 5beta1 Heterodimerization, Expression on the Cell Surface, and Its Biological Function
T. Isaji et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M607771200CKAP4/p63 Is a Receptor for the Frizzled-8 Protein-related Antiproliferative Factor from Interstitial Cystitis Patients
T. P. Conrads et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604581200Sialoadhesin deficiency ameliorates myelin degeneration and axonopathic changes in the CNS of PLP overexpressing mice
C Ip et al.
Original research paper: Neurobiology of Disease 25
doi:10.1016/j.nbd.2006.08.023A male contraceptive targeting germ cell adhesion
Dolores D Mruk, Ching-Hang Wong, Bruno Silvestrini and C Yan Cheng
Original research paper: Nature Medicine 12 1323-1328 (2006)
doi:10.1038/nm1420Down-regulation of 1,4-galactosyltransferase V is a critical part of etoposide-induced apoptotic process and could be mediated by decreasing Sp1 levels in human glioma cells
J. Jiang
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl027Oligosaccharides modulate the apoptotic activity of glycodelin
R. Jayachandran
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl024Preferential transfer of the complete glycan is determined by the oligosaccharyltransferase complex and not by the catalytic subunit
O. Castro, F. Movsichoff and A. J. Parodi
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0607086103Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module
X. Zhou et al.
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0602954103N-Acetylglucosaminyltransferase III Antagonizes the Effect of N-Acetylglucosaminyltransferase V on 3beta1 Integrin-mediated Cell Migration
Y. Zhao et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M607274200Fucosylation of N-Glycans Regulates the Secretion of Hepatic Glycoproteins into Bile Ducts
T. Nakagawa
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605697200UDP-Gal: GlcNAc-R β1,4-galactosyltransferase—a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme
Inka Brockhausen et al.
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-7153-xComparative characterisation of recombinant invertebrate and vertebrate peptide O-Xylosyltransferases
Andrea Brunner et al.
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-7633-zCloning and biochemical characterization of the fucanase FcnA: definition of a novel glycoside hydrolase family specific for sulfated fucans
S. Colin
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl029Procyclic Trypanosoma brucei Expresses Separate Sialidase and trans-Sialidase Enzymes on Its Surface Membrane
G. N. Montagna, J. E. Donelson and A. C. C. Frasch
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604951200Identification of Common and Unique Peptide Substrate Preferences for the UDP-GalNAc:Polypeptide -N-acetylgalactosaminyltransferases T1 and T2 Derived from Oriented Random Peptide Substrates
T. A. Gerken, J. Raman, T. A. Fritz and O. Jamison
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605149200Substrate Specificity Analysis of Endoplasmic Reticulum Glucosidase II Using Synthetic High Mannose-type Glycans
K. Totani, Y. Ihara, I. Matsuo and Y. Ito
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605457200Polysialic Acid Profiles of Mice Expressing Variant Allelic Combinations of the Polysialyltransferases ST8SiaII and ST8SiaIV
S. P. Galuska et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M606516200The CMP-sialic Acid Transporter Is Localized in the Medial-Trans Golgi and Possesses Two Specific Endoplasmic Reticulum Export Motifs in Its Carboxyl-terminal Cytoplasmic Tail
W. Zhao, T.-L. L. Chen, B. M. Vertel and K. J. Colley
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M605564200Roles for UDP-GlcNAc 2-Epimerase/ManNAc 6-Kinase outside of Sialic Acid Biosynthesis: MODULATION OF SIALYLTRANSFERASE AND BiP EXPRESSION, GM3 AND GD3 BIOSYNTHESIS, PROLIFERATION, AND APOPTOSIS, AND ERK1/2 PHOSPHORYLATION
Z. Wang
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M604903200Exploiting the Reversibility of Natural Product Glycosyltransferase-Catalyzed Reactions
C. Zhang
Original research paper: Science 313
doi:10.1126/science.1130028Modification of p53 with O-linked N-acetylglucosamine regulates p53 activity and stability
Won Ho Yang et al.
Original research paper: Nature Cell Biology 8 1074-1083 (2006)
doi:10.1038/ncb1470Differentiation elicits negative regulation of human β-galactoside α2,6-sialyltransferase at the mRNA level in the HL-60 cell line
A Taniguchi
Original research paper: FEBS Letters 441
doi:10.1016/S0014-5793(98)01548-8Unique disialosyl gangliosides from salmon kidney: Characterization of V3αFuc, IV3βGalNAc, II3(αNeuAc)2-Gg4Cer and its analogue with 4-O-acetyl-N-acetylneuraminic acid
Yukio Niimura and Ineo Ishizuka
Original research paper: Glycoconjugate Journal 23
doi:10.1007/s10719-006-6562-1Genetic mechanisms for the synthesis of fucosyl GM1 in small cell lung cancer cell lines
N. Tokuda
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl022Serglycin Is the Major Secreted Proteoglycan in Macrophages and Has a Role in the Regulation of Macrophage Tumor Necrosis Factor- Secretion in Response to Lipopolysaccharide
L. Zernichow
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M512889200G-CSF induces E-selectin ligand expression on human myeloid cells
Nilesh M Dagia et al.
Original research paper: Nature Medicine 12 1185-1190 (2006)
doi:10.1038/nm1470Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45
Sandra J Van vliet, Sonja I Gringhuis, Teunis B H Geijtenbeek and Yvette Van kooyk
Original research paper: Nature Immunology 7 1200-1208 (2006)
doi:10.1038/ni1390Galectin-8 and galectin-9 are novel substrates for thrombin
N. Nishi
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl028Chondroitin Sulfate Perlecan Enhances Collagen Fibril Formation: IMPLICATIONS FOR PERLECAN CHONDRODYSPLASIAS
A. J. Kvist et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M607892200Heparan Sulfate-related Oligosaccharides in Ternary Complex Formation with Fibroblast Growth Factors 1 and 2 and Their Receptors
N. Jastrebova
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M600806200Matrix morphogenesis in cornea is mediated by the modification of keratan sulfate by GlcNAc 6-O-sulfotransferase
Y. Hayashida
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0605441103Arraying glycomics: a novel bi-functional spacer for one-step microscale derivatization of free reducing glycans
O. Bohorov, H. Andersson-sand, J. Hoffmann and O. Blixt
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl044Lectindb: a plant lectin database
N. R. Chandra
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl012Search for glucose/galactose-binding proteins in newly discovered protein sequences using molecular modeling techniques and structural analysis
M. Patra
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl021Glycan microarray technologies: tools to survey host specificity of influenza viruses
James Stevens, Ola Blixt, James C. Paulson and Ian A. Wilson
Original research paper: Nature Reviews Microbiology 4 857-864 (2006)
doi:10.1038/nrmicro1530Mining the Molecules That Made Our Mind
E. Pennisi
Original research paper: Science 313
doi:10.1126/science.313.5795.1908Down-regulation of trypsinogen expression is associated with growth retardation in 1,6-fucosyltransferase-deficient mice: attenuation of proteinase-activated receptor 2 activity
W. Li
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl023Identification of core 1 O-glycan T-synthase from Caenorhabditis elegans
T. Ju
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl008Isomer and glycomer complexities of core GlcNAcs in Caenorhabditis elegans
A. J. Hanneman
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl011A Mutant Chaperone Converts a Wild-Type Protein into a Tumor-Specific Antigen
A. Schietinger et al.
Original research paper: Science 314
doi:10.1126/science.1129200Characteristics of two CD75-related cell-surface expressed antigens of human lymphocytes
W Eichler
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2006.09.017Use of lectins for probing differentiated human embryonic stem cells for carbohydrates
K. A. Wearne
Original research paper: Glycobiology 16
doi:10.1093/glycob/cwl019Neuroglycan C Is a Novel Midkine Receptor Involved in Process Elongation of Oligodendroglial Precursor-like Cells
K. Ichihara-tanaka, A. Oohira, M. Rumsby and T. Muramatsu
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M602228200Siglec-7 Undergoes a Major Conformational Change When Complexed with the (2,8)-Disialylganglioside GT1b
H. Attrill et al.
Original research paper: Journal of Biological Chemistry 281
doi:10.1074/jbc.M601714200Thrombocytopenia and kidney disease in mice with a mutation in the C1galt1 gene
W. S. Alexander et al.
Original research paper: Proceedings of the National Academy of Sciences 103
doi:10.1073/pnas.0607872103