Research library: browse by date
The Research Library categorizes and provides access to all recent glycobiology-related research published by Nature Publishing Group and other journals. The selection is deliberately broad to facilitate access to all research impacting on the glycobiology community. Both primary research and review articles are included.
April 2007
Siglecs and their roles in the immune system
Paul R. Crocker, James C. Paulson & Ajit Varki
Original research paper: Nature Reviews Immunology 7 255-266
doi:10.1038/nri2056The crystal structure of two macrolide glycosyltransferases provides a blueprint for host cell antibiotic immunity
D. N. Bolam et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0607897104Tinkering with heparan sulfate sulfation to steer development
B Gorsi & S Stringer
Original research paper: Trends in Cell Biology
doi:10.1016/j.tcb.2007.02.006Langerin is a natural barrier to HIV-1 transmission by Langerhans cells
Lot De witte et al.
Original research paper: Nature Medicine 13 367-371 (2007)
doi:10.1038/nm1541Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs
Krystle M Veerman et al.
Original research paper: Nature Immunology
doi:10.1038/ni1456Structures of the Cd44–hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction
Suneale Banerji et al.
Original research paper: Nature Structural & Molecular Biology 14 234-239 (2007)
doi:10.1038/nsmb1201Carbohydrate-binding properties of goat secretory glycoprotein (SPG-40) and its functional implications: structures of the native glycoprotein and its four complexes with chitin-like oligosaccharides
Janesh Kumar et al.
Original research paper: Acta Crystallographica Section D Biological Crystallography 63
doi:10.1107/S0907444907001631HIV entry inhibition by the envelope 2 glycoprotein of GB virus C
Susan Jung et al.
Original research paper: AIDS 21
doi:10.1097/QAD.0b013e32803277c7Analysis of glycans in glycoproteins by diffusion-ordered nuclear magnetic resonance spectroscopy
Karin Ortner, Veeramuthu N. Sivanandam, Wolfgang Buchberger & Norbert Müller
Original research paper: Analytical and Bioanalytical Chemistry 388
doi:10.1007/s00216-007-1232-0Nonlabeled Quartz Crystal Microbalance Biosensor for Bacterial Detection Using Carbohydrate and Lectin Recognitions
Z. Shen et al.
Original research paper: Analytical Chemistry 79
doi:10.1021/ac061986jMutational analysis of the N-glycosylation sites of Duffy antigen/receptor for chemokines
M Czerwinski et al.
Original research paper: Biochemical and Biophysical Research Communications 356
doi:10.1016/j.bbrc.2007.03.054Positive regulation of tumor necrosis factor-α by ganglioside GM3 through Akt in mouse melanoma B16 cells
P Wang et al.
Original research paper: Biochemical and Biophysical Research Communications
doi:10.1016/j.bbrc.2007.02.152Shed gangliosides provide detergent-independent evidence for Type-3 glycosynapses
R Thorne, N Mhaidat, K Ralston & G Burns
Original research paper: Biochemical and Biophysical Research Communications 356
doi:10.1016/j.bbrc.2007.02.139Identification of the nuclear export signals that regulate the intracellular localization of the mouse CMP-sialic acid synthetase
A Fujita, C Sato & K Kitajima
Original research paper: Biochemical and Biophysical Research Communications 355
doi:10.1016/j.bbrc.2007.01.139Drosophila β1,4-N-acetylgalactosaminyltransferase-A synthesizes the LacdiNAc structures on several glycoproteins and glycosphingolipids
N Sasaki et al.
Original research paper: Biochemical and Biophysical Research Communications 354
doi:10.1016/j.bbrc.2007.01.015Identification and expression of a sialyltransferase responsible for the synthesis of disialylgalactosylgloboside in normal and malignant kidney cells: downregulation of ST6GalNAc VI in renal cancers
Motohiro Senda et al.
Original research paper: Biochemical Journal 402
doi:10.1042/BJ20061118Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling
Manabu Kurayoshi, Hideki Yamamoto, Shunsuke Izumi & Akira Kikuchi
Original research paper: Biochemical Journal 402
doi:10.1042/BJ20061476Kinetic and Structural Studies on Interactions between Heparin or Heparan Sulfate and Proteins of the Hedgehog Signaling Pathway
F. Zhang et al.
Original research paper: Biochemistry 46
doi:10.1021/bi6025424FGFR3 intracellular mutations induce tyrosine phosphorylation in the Golgi and defective glycosylation
L Gibbs & L Legeaimallet
Original research paper: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1773
doi:10.1016/j.bbamcr.2006.12.010Structural characterization of a rhamnose-binding glycoprotein (lectin) from Spanish mackerel (Scomberomorous niphonius) eggs
T Terada et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - General Subjects 1770
doi:10.1016/j.bbagen.2006.11.003Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose
R Agusti et al.
Original research paper: Bioorganic & Medicinal Chemistry 15
doi:10.1016/j.bmc.2007.01.045Variations in glycosylation of von Willebrand factor with O-linked sialylated T antigen are associated with its plasma levels
C. J. M. Van schooten et al.
Original research paper: Blood 109
doi:10.1182/blood-2006-06-032706Synthesis of glycosylated human tumor necrosis factor α coupled with N-acetylneuraminic acid
Akiko Hayashi et al.
Original research paper: Cancer Immunology, Immunotherapy 56
doi:10.1007/s00262-006-0209-8Regulation of galectin-1 expression by transforming growth factor β1 in metastatic mammary adenocarcinoma cells: implications for tumor-immune escape
Cecilia M. Daroqui et al.
Original research paper: Cancer Immunology, Immunotherapy 56
doi:10.1007/s00262-006-0208-9Glycoconjugate profiling of primary melanoma and its sentinel node and distant metastases: Implications for diagnosis and pathophysiology of metastases
A Thies et al.
Original research paper: Cancer Letters 248
doi:10.1016/j.canlet.2006.05.020LC-MS/MS Quantification of Zn-α2 Glycoprotein: A Potential Serum Biomarker for Prostate Cancer
O. P. Bondar et al.
Original research paper: Clinical Chemistry 53
doi:10.1373/clinchem.2006.079681Sialic acids: carbohydrate moieties that influence the biological and physical properties of biopharmaceutical proteins and living cells
B Byrne, G Donohoe & R Okennedy
Original research paper: Drug Discovery Today 12
doi:10.1016/j.drudis.2007.02.010Glypican-3: From the mutations of Simpson–Golabi–Behmel genetic syndrome to a tumor marker for hepatocellular carcinoma
B Jakubovic & S Jothy
Original research paper: Experimental and Molecular Pathology 82
doi:10.1016/j.yexmp.2006.10.010Matrix metalloproteinases and proteoglycans in axonal regeneration
M Pizzi & M Crowe
Original research paper: Experimental Neurology 204
doi:10.1016/j.expneurol.2006.12.012PANVACTM-VF: poxviral-based vaccine therapy targeting CEA and MUC1 in carcinoma
Ravi A Madan, Philip M Arlen & James L Gulley
Original research paper: Expert Opinion on Biological Therapy 7
doi:10.1517/14712598.7.4.543Ammonia secretion from fish gill depends on a set of Rh glycoproteins
T. Nakada, C. M. Westhoff, A. Kato & S. Hirose
Original research paper: The FASEB Journal 21
doi:10.1096/fj.06-6834comMannan-modified adenovirus as a vaccine to induce antitumor immunity
Z-Y Ding et al.
Original research paper: Gene Therapy 14 657-663 (2007)
doi:10.1038/sj.gt.3302893Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a
Hideyuki Komekado, Hideki Yamamoto, Tsutomu Chiba & Akira Kikuchi
Original research paper: Genes to Cells 12
doi:10.1111/j.1365-2443.2007.01068.xPurification and structural characterization of de-N-acetylated form of GD3 ganglioside present in human melanoma tumors
I. Popa et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm006Glycosylation of serum ribonuclease 1 indicates a major endothelial origin and reveals an increase in core fucosylation in pancreatic cancer
S. Barrabes et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm002Comparison of the methods for profiling glycoprotein glycans--HUPO Human Disease Glycomics/Proteome Initiative multi-institutional study
Y. Wada et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl086Carbohydrate-recognition domains of galectin-9 are involved in intermolecular interaction with galectin-9 itself and other members of the galectin family
N. Miyanishi et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm001The lectin domains of polypeptide GalNAc-transferases exhibit carbohydrate-binding specificity for GalNAc: lectin binding to GalNAc-glycopeptide substrates is required for high density GalNAc-O-glycosylation
H. H. Wandall et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl082Virus-induced transcriptional activation of host FUT genes associated with neo-expression of Ley in cytomegalovirus-infected and sialyl-Lex in varicella-zoster virus-infected diploid human cells
K. Nystrom et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwl083Reduced sialylation status in UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase (GNE)-deficient mice
Daniel Gagiannis et al.
Original research paper: Glycoconjugate Journal 24
doi:10.1007/s10719-006-9019-7Expression of β-1,4-Galactosyltransferase-I in Rat during Inflammation
Ji Qian et al.
Original research paper: Inflammation 30
doi:10.1007/s10753-007-9022-6Modifications of surface carbohydrates on bovine spermatozoa mediated by oviductal fluid: a flow cytometric study using lectins
Ioannis A. Taitzoglou, Alexandra N. Kokoli & Gary J. Killian
Original research paper: International Journal of Andrology 30
doi:10.1111/j.1365-2605.2006.00717.xChondroitin sulfate glycosaminoglycans as major P-selectin ligands on metastatic breast cancer cell lines
Behjatolah Monzavi-karbassi et al.
Original research paper: International Journal of Cancer 120
doi:10.1002/ijc.22424Site-Specific Incorporation of Glycosylated Serine and Tyrosine Derivatives into Proteins
N.E. Fahmi et al.
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja067466nAutomated Synthesis of the Tumor-Associated Carbohydrate Antigens Gb-3 and Globo-H: Incorporation of α-Galactosidic Linkages
D.B. Werz, B. Castagner & P.H. Seeberger
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja069218xGolgi GDP-fucose Transporter-deficient Mice Mimic Congenital Disorder of Glycosylation IIc/Leukocyte Adhesion Deficiency II
C. C. Hellbusch et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M700314200Identification of a Glycosaminoglycan Binding Region of the Alpha C Protein That Mediates Entry of Group B Streptococci into Host Cells
M. J. Baron et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M608279200Impact of Carrier Stiffness and Microtopology on Two-dimensional Kinetics of P-selectin and P-selectin Glycoprotein Ligand-1 (PSGL-1) Interactions
L. Wu et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M609219200Structural Effects of Naturally Occurring Human Blood Group B Galactosyltransferase Mutations Adjacent to the DXD Motif
M. Persson et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M610998200Structure and Mechanism of Helicobacter pylori Fucosyltransferase: A BASIS FOR LIPOPOLYSACCHARIDE VARIATION AND INHIBITOR DESIGN
H.-Y. Sun et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M610285200Dynamic Developmental Elaboration of N-Linked Glycan Complexity in the Drosophila melanogaster Embryo
K. Aoki et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M606711200Expression of rib-1, a Caenorhabditis elegans Homolog of the Human Tumor Suppressor EXT Genes, Is Indispensable for Heparan Sulfate Synthesis and Embryonic Morphogenesis
H. Kitagawa et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611107200Ganglioside GM2-Tetraspanin CD82 Complex Inhibits Met and Its Cross-talk with Integrins, Providing a Basis for Control of Cell Motility through Glycosynapse
A. R. Todeschini, J. N. Dos santos, K. Handa & S.-i. Hakomori
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611407200Ganglioside GD1a Is an Essential Coreceptor for Toll-like Receptor 2 Signaling in Response to the B subunit of Type IIb Enterotoxin
S. Liang et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611722200Human Follicular Lymphoma Cells Contain Oligomannose Glycans in the Antigen-binding Site of the B-cell Receptor
C. M. Radcliffe et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M602690200Serine scanning—A tool to prove the consequences of N-glycosylation of proteins
R Weis, R Gaisberger, K Gruber & A Glieder
Original research paper: Journal of Biotechnology 129
doi:10.1016/j.jbiotec.2006.12.001Alternative isoforms of myelin/oligodendrocyte glycoprotein with variable cytoplasmic domains are expressed in human brain
Chantal Allamargot & Minnetta V. Gardinier
Original research paper: Journal of Neurochemistry 101
doi:10.1111/j.1471-4159.2006.04296.xConformational Behavior of Basic Monomeric Building Units of Glycosaminoglycans: Isolated Systems and Solvent Effect
M. Remko, M. Swart & F.M. Bickelhaupt
Original research paper: Journal of Physical Chemistry B 111
doi:10.1021/jp0646271Mutation in the Glycosylated Gag Protein of Murine Leukemia Virus Results in Reduced In Vivo Infectivity and a Novel Defect in Viral Budding or Release
A. Low et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.01538-06Antigenic and Mutational Analyses of Herpes Simplex Virus Glycoprotein B Reveal Four Functional Regions
F. C. Bender et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.02710-06A Second Receptor Binding Site on Human Parainfluenza Virus Type 3 Hemagglutinin-Neuraminidase Contributes to Activation of the Fusion Mechanism
M. Porotto, M. Fornabaio, G. E. Kellogg & A. Moscona
Original research paper: Journal of Virology 81
doi:10.1128/JVI.02617-06Sialic Acid on Herpes Simplex Virus Type 1 Envelope Glycoproteins Is Required for Efficient Infection of Cells
J. R. Teuton & C. R. Brandt
Original research paper: Journal of Virology 81
doi:10.1128/JVI.02250-06Heparan and chondroitin sulfate on growth plate perlecan mediate binding and delivery of FGF-2 to FGF receptors
S Smith et al.
Original research paper: Matrix Biology 26
doi:10.1016/j.matbio.2006.10.012Scanning N-glycosylation mutagenesis of membrane proteins
J Cheung & R Reithmeier
Original research paper: Methods 41
doi:10.1016/j.ymeth.2006.10.002Gangliosides, Ab1 and Ab2 antibodiesIV. Dominance of VH domain in the induction of anti-idiotypic antibodies by gene gun immunization
A Lopezrequena et al.
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2007.01.020Drosophila C-type lectins enhance cellular encapsulation
J Ao, E Ling & X Yu
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2006.12.024Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteins
J Moore et al.
Original research paper: Molecular Immunology 44
doi:10.1016/j.molimm.2006.12.011Rolling on N-linked glycans: a new way to present L-selectin binding sites
Ronen Alon & Steven Rosen
Original research paper: Nature Immunology 8 339-341
doi:10.1038/ni0407-339Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment
Junya Mitoma et al.
Original research paper: Nature Immunology 8 409-418 (2007)
doi:10.1038/ni1442Glycan chains modulate prion protein binding to immobilized metal ions
M Moudjou et al.
Original research paper: Neurochemistry International 50
doi:10.1016/j.neuint.2007.01.001The conformational behaviour and P-selectin inhibition of fluorine-containing sialyl LeX glycomimetics
Javier Pérez-castells et al.
Original research paper: Organic & Biomolecular Chemistry 5
doi:10.1039/b615752aCarbohydrate post-glycosylational modifications
Hai Yu & Xi Chen
Original research paper: Organic & Biomolecular Chemistry 5
doi:10.1039/b700034kNeoglycopeptide Dendrimer Libraries as a Source of Lectin Binding Ligands
E. Kolomiets et al.
Original research paper: Organic Letters 9
doi:10.1021/ol070119dGlycosaminoglycan Interactions in Murine Gammaherpesvirus-68 Infection
Laurent Gillet, Heiko Adler, Philip G. Stevenson & Olivier Schwartz
Original research paper: PLoS ONE 2
doi:10.1371/journal.pone.0000347Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
T. Mizushima et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0610312104Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis
Y. Yuan et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0701160104Noninfectious entry of HIV-1 into peripheral and brain macrophages mediated by the mannose receptor
J. R. Trujillo et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0611263104Separation of receptor-binding and profusogenic domains of glycoprotein D of herpes simplex virus 1 into distinct interacting proteins
G. Zhou & B. Roizman
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0611565104Apical Sorting by Galectin-3-Dependent Glycoprotein Clustering
Delphine Delacour et al.
Original research paper: Traffic 8
doi:10.1111/j.1600-0854.2007.00539.xIntegrating transcriptome, proteome and glycome analyses of Schistosoma biology
C Hokke, J Fitzpatrick & K Hoffmann
Original research paper: Trends in Parasitology 23
doi:10.1016/j.pt.2007.02.007Carbohydrate profiling and protein identification of tegumental and excreted/secreted glycoproteins of adult Schistosoma bovis worms
A Ramajohernandez, A Oleaga, V Ramajomartin & R Perezsanchez
Original research paper: Veterinary Parasitology 144
doi:10.1016/j.vetpar.2006.09.034Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteins
D Kothe et al.
Original research paper: Virology 360
doi:10.1016/j.virol.2006.10.017Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1
A Dey, K David, P Klasse & J Moore
Original research paper: Virology 360
doi:10.1016/j.virol.2006.09.046Characterization of the Epstein–Barr virus glycoprotein BMRF-2
J Xiao, J Palefsky, R Herrera & S Tugizov
Original research paper: Virology 359
doi:10.1016/j.virol.2006.09.047Synthesis of complex-type glycans derived from parasitic helminths
J Nakano, A Ishiwata, H Ohta & Y Ito
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.022Functionalization of oligosaccharide mimetics and multimerization using squaric diester-mediated coupling
O Sperling, M Dubber & T Lindhorst
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.021Structure elucidation of arabinoxylan isomers by normal phase HPLC–MALDI-TOF/TOF-MS/MS
S Maslen et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.007Unexpected regioselectivity of Humicola insolens Cel7B glycosynthase mutants
S Blanchard et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.017The O-chain structure from the LPS of the bacterium Naxibacter alkalitolerans YIM 31775T
A Silipo et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2006.12.012