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Specially written reviews on the most exiting new findings in glycobiology. For Nature Group Publishing articles, free full access to the publication will be maintained for three months.
July 2007
Intracellular glycosylation: A QUICtag for GlcNAc
A new combination of tagging, isotope labeling and peptide fragmentation by electron transfer enables the analysis of N–acetylglucosamine (GlcNAc) glycosylation dynamics and identification of GlcNAcylated protein sites.
Original research paper: Nat. Chem. Biol. 3, 339-348 (2007)
doi:10.1038/nchembio881DC-SIGN signaling: Good receptor, bad receptor
The DC-SIGN receptor can promote two distinct cellular responses when activated: increasing NF-
B activity through acetylation by stimulating the Ras/Raf-1 pathway, and Rho GTPase activation through binding to the Rho GEF LARG.Original research paper: Immunity 26, 605-616 (2007)
doi:10.1016/j.immuni.2007.03.012