Research library: browse by date
The Research Library categorizes and provides access to all recent glycobiology-related research published by Nature Publishing Group and other journals. The selection is deliberately broad to facilitate access to all research impacting on the glycobiology community. Both primary research and review articles are included.
August 2007
Immunology: How a T cell sees sugar
D. Branch Moody
Original research paper: Nature (2007)
doi:10.1038/nature05890The Threonine That Carries Fucose, but Not Fucose, Is Required for Cripto to Facilitate Nodal Signaling
S. Shi et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702593200CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor
Natalie A. Borg et al.
Original research paper: Nature (2007)
doi:10.1038/nature05907Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death
Marta A Toscano et al.
Original research paper: Nature Immunology 8 825-834 (2007)
doi:10.1038/ni1482Crystal structure of the extracellular domain of nAChR
1 bound to -bungarotoxin at 1.94 Å resolutionCosma D Dellisanti et al.
Original research paper: Nature Neuroscience 10 953-962 (2007)
doi:10.1038/nn1942Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy
Jan Balzarini
Original research paper: Nature Reviews Microbiology 5 583-597
doi:10.1038/nrmicro1707α1,3-Galactosyltransferase Gene-Knockout Pigs for Xenotransplantation: Where Do We Go From Here?
David K. C. Cooper et al.
Original research paper: Transplantation 84
doi:10.1097/01.tp.0000260427.75804.f2Gal Knockout Pigs: Any More Carbohydrates?
Mauro S. Sandrin
Original research paper: Transplantation 84
doi:10.1097/01.tp.0000269728.11879.f6Building on the GalKO Platform
Anthony J. F. D'Apice & Peter J. Cowan
Original research paper: Transplantation 84
doi:10.1097/01.tp.0000269740.59820.ceGalT-KO Pigs: Is the Cup Half Empty or Half Full?
David H. Sachs et al.
Original research paper: Transplantation 84
doi:10.1097/01.tp.0000269729.68625.08Chemoenzymatic approaches to glycoprotein synthesis
Clay S. Bennett & Chi-Huey Wong
Original research paper: Chemical Society Reviews 36
doi:10.1039/b617709cMUC1 cell surface mucin is a critical element of the mucosal barrier to infection
Julie L. Mcauley et al.
Original research paper: Journal of Clinical Investigation 117
doi:10.1172/JCI26705The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation
S. Banerjee et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0704862104A ratiometric lectin microarray approach to analysis of the dynamic mammalian glycome
K. T. Pilobello, D. E. Slawek & L. K. Mahal
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0704954104Extracellular structure of polysialic acid explored by on cell solution NMR
H. F. Azurmendi et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0704404104Tumor-derived hyaluronan induces formation of immunosuppressive macrophages through transient early activation of monocytes
D.-M. Kuang et al.
Original research paper: Blood 110
doi:10.1182/blood-2007-01-068031Diverging signaling events control the pathway of GPVI down-regulation in vivo
T. Rabie et al.
Original research paper: Blood 110
doi:10.1182/blood-2006-11-058107Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress
J.-J. Chiu et al.
Original research paper: Blood 110
doi:10.1182/blood-2006-08-040097C-reactive protein collaborates with plasma lectins to boost immune response against bacteria
Original research paper: The EMBO Journal 26 3431-3440
doi:10.1038/sj.emboj.7601762Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cells
S. Sirko et al.
Original research paper: Development 134
doi:10.1242/dev.02871Serine versus Threonine Glycosylation: The Methyl Group Causes a Drastic Alteration on the Carbohydrate Orientation and on the Surrounding Water Shell
F. Corzana et al.
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja072181bWeak Calcium-Mediated Interactions between Lewis X-Related Trisaccharides Studied by NMR Measurements of Residual Dipolar Couplings
G. Nodet et al.
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja0711056Imaging Cell Surface Glycans with Bioorthogonal Chemical Reporters
P.V. Chang, J.A. Prescher, M.J. Hangauer & C.R. Bertozzi
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja070238oPituitary glycoprotein hormone receptors in non-endocrine organs
H Blair, A Wells & C Isales
Original research paper: Trends in Endocrinology & Metabolism 18
doi:10.1016/j.tem.2007.06.001Interpretation support for multistage MS: A mathematical method for theoretical generation of glycan fragments and calculation of their masses
Ningombam Sanjib Meitei & Snigdha Banerjee
Original research paper: PROTEOMICS 7
doi:10.1002/pmic.200600667N-Glycan Structure Annotation of Glycopeptides Using a Linearized Glycan Structure Database (GlyDB)
J.M. Ren, T. Rejtar, L. Li & B.L. Karger
Original research paper: Journal of Proteome Research 6
doi:10.1021/pr070111yAn Enzymatic Deglycosylation Scheme Enabling Identification of Core Fucosylated N-Glycans and O-Glycosylation Site Mapping of Human Plasma Proteins
P. Hagglund et al.
Original research paper: Journal of Proteome Research 6
doi:10.1021/pr0700605Proteomic analysis of N-glycosylation in mosquito dopachrome conversion enzyme
Junsuo S. Li, Christopher J. Vavricka, Bruce M. Christensen & Jianyong Li
Original research paper: PROTEOMICS 7
doi:10.1002/pmic.200601053Functions of Chondroitin Sulfate/Dermatan Sulfate Chains in Brain Development: CRITICAL ROLES OF E AND iE DISACCHARIDE UNITS RECOGNIZED BY A SINGLE CHAIN ANTIBODY GD3G7
A. Purushothaman et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M700630200Essential Role of Heparan Sulfate 2-O-Sulfotransferase in Chick Limb Bud Patterning and Development
T. Kobayashi et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M610707200Osteopontin Overexpression Inhibits in Vitro Re-endothelialization via Integrin Engagement
D. Leali, E. Moroni, F. Bussolino & M. Presta
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M606938200Control of T Cell-mediated Autoimmunity by Metabolite Flux to N-Glycan Biosynthesis
A. Grigorian et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M701890200Regulation of Mammalian Protein O-Mannosylation: PREFERENTIAL AMINO ACID SEQUENCE FOR O-MANNOSE MODIFICATION
H. Manya et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702369200Inducible Hyaluronan Production Reveals Differential Effects on Prostate Tumor Cell Growth and Tumor Angiogenesis
A. G. Bharadwaj, K. Rector & M. A. Simpson
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702964200The Extremely Conserved C-terminal Region of Reelin Is Not Necessary for Secretion but Is Required for Efficient Activation of Downstream Signaling
Y. Nakano et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702300200O-Linked Glycosylation at Threonine 27 Protects the Copper Transporter hCTR1 from Proteolytic Cleavage in Mammalian Cells
E. B. Maryon, S. A. Molloy & J. H. Kaplan
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M701806200Phosphorylated Galectin-3 Mediates Tumor Necrosis Factor-related Apoptosis-inducing Ligand Signaling by Regulating Phosphatase and Tensin Homologue Deleted on Chromosome 10 in Human Breast Carcinoma Cells
N. Mazurek et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M608810200Recognition Mechanism of Galectin-4 for Cholesterol 3-Sulfate
H. Ideo, A. Seko & K. Yamashita
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M703770200Inhibition of a Specific N-Glycosylation Activity Results in Attenuation of Breast Carcinoma Cell Invasiveness-related Phenotypes: INHIBITION OF EPIDERMAL GROWTH FACTOR-INDUCED DEPHOSPHORYLATION OF FOCAL ADHESION KINASE
H.-B. Guo, M. Randolph & M. Pierce
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611518200Identification of CLEC12B, an Inhibitory Receptor on Myeloid Cells
S. C. Hoffmann et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704250200Membrane Glycoprotein M6a Interacts with the µ-Opioid Receptor and Facilitates Receptor Endocytosis and Recycling
D.-F. Wu et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M700941200Distinct Endocytic Mechanisms of CD22 (Siglec-2) and Siglec-F Reflect Roles in Cell Signaling and Innate Immunity
H. Tateno et al.
Original research paper: Molecular and Cellular Biology 27
doi:10.1128/MCB.00383-07Neisseria gonorrhoeae O-linked pilin glycosylation: functional analyses define both the biosynthetic pathway and glycan structure
Finn Erik Aas et al.
Original research paper: Molecular Microbiology 65
doi:10.1111/j.1365-2958.2007.05806.xTransforming Growth Factor α-Dependent Cancer Progression Is Modulated by Muc1
M. R. Pochampalli, B. G. Bitler & J. A. Schroeder
Original research paper: Cancer Research 67
doi:10.1158/0008-5472.CAN-06-4518Molecular basis for acceptor substrate specificity of the human α1,3-glucuronosyltransferases GlcAT-I and GlcAT-P involved in glycosaminoglycan and HNK-1 carbohydrate epitope biosynthesis, respectively
M. Fondeur-gelinotte et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm055O-linked glycan expression during Drosophila development
E Tian & K. G T. Hagen
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm056Anti-asthmatic potential of a D-galactose-binding lectin from Synadenium carinatum latex
A. P Rogerio et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm053Glycosaminoglycans in Hydra magnipapillata (Hydrozoa, Cnidaria): demonstration of chondroitin in the developing nematocyst, the sting organelle, and structural characterization of glycosaminoglycans
S. Yamada, H. Morimoto, T. Fujisawa & K. Sugahara
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm051NetCGlyc 1.0: prediction of mammalian C-mannosylation sites
K. Julenius
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm050High-throughput carbohydrate microarray profiling of 27 antibodies demonstrates widespread specificity problems
J. C Manimala, T. A Roach, Z. Li & J. C Gildersleeve
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm047Metabolic homeostasis and tissue renewal are dependent on β1,6GlcNAc-branched N-glycans
P. Cheung et al.
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm048Siglec-15: an immune system Siglec conserved throughout vertebrate evolution
T. Angata, Y. Tabuchi, K. Nakamura & M. Nakamura
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm049Mgat5 and Pten interact to regulate cell growth and polarity
P. Cheung & J. W. Dennis
Original research paper: Glycobiology 17
doi:10.1093/glycob/cwm037Characterization of the Fucosylation Pathway in the Biosynthesis of Glycopeptidolipids from Mycobacterium avium Complex
Y. Miyamoto et al.
Original research paper: Journal of Bacteriology 189
doi:10.1128/JB.00344-07Lectin-Based Food Poisoning: A New Mechanism of Protein Toxicity
Katsuya Miyake, Toru Tanaka, Paul L. Mcneil & Richard Steinhardt
Original research paper: PLoS ONE 2
doi:10.1371/journal.pone.0000687Glycosylation and annexin II cell surface translocation mediate airway epithelial wound repair
B. J. Patchell et al.
Original research paper: AJP: Lung Cellular and Molecular Physiology 293
doi:10.1152/ajplung.00412.2006Changes in versican and chondroitin sulfate proteoglycans during structural development of the lung
J. Faggian et al.
Original research paper: AJP: Regulatory, Integrative and Comparative Physiology 293
doi:10.1152/ajpregu.00801.2006Epithelial Cell Adhesion Molecule: More than a Carcinoma Marker and Adhesion Molecule
M. Trzpis, P. M.J. Mclaughlin, L. M.F.H. De leij & M. C. Harmsen
Original research paper: American Journal Of Pathology 171
doi:10.2353/ajpath.2007.070152Tags for the Stable Isotopic Labeling of Carbohydrates and Quantitative Analysis by Mass Spectrometry
M.J. Bowman & J. Zaia
Original research paper: Analytical Chemistry 79
doi:10.1021/ac070581bIsolation of N-Linked Glycopeptides from Plasma
Y. Zhou, R. Aebersold & H. Zhang
Original research paper: Analytical Chemistry 79
doi:10.1021/ac0623181Analysis of Cell Surface Carbohydrate Expression Patterns in Normal and Tumorigenic Human Breast Cell Lines Using Lectin Arrays
S. Chen et al.
Original research paper: Analytical Chemistry 79
doi:10.1021/ac070423kMetabolic Cytometry. Glycosphingolipid Metabolism in Single Cells
C.D. Whitmore et al.
Original research paper: Analytical Chemistry 79
doi:10.1021/ac070716dRole of galectin-3 in prion infections of the CNS
S Mok et al.
Original research paper: Biochemical and Biophysical Research Communications 359
doi:10.1016/j.bbrc.2007.05.163Crucial roles of binding sites for NF-κB and C/EBPs in IκB-ζ-mediated transcriptional activation
Susumu Matsuo, Soh Yamazaki, Koichiro Takeshige & Tatsushi Muta
Original research paper: Biochemical Journal 405
doi:10.1042/BJ20061797A Haemophilus influenzae Strain Associated with Fisher Syndrome Expresses a Novel Disialylated Ganglioside Mimic
R.S. Houliston et al.
Original research paper: Biochemistry 46
doi:10.1021/bi700685sProteoglycans: key partners in bone cell biology
François Lamoureux et al.
Original research paper: BioEssays 29
doi:10.1002/bies.20612Lectin-modified microchannels for mammalian cell capture and purification
Ting Zheng et al.
Original research paper: Biomedical Microdevices 9
doi:10.1007/s10544-007-9074-2The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma
Eirikur Saeland et al.
Original research paper: Cancer Immunology, Immunotherapy 56
doi:10.1007/s00262-006-0274-zDifferences in tropism and pH dependence for glycoproteins from the Clade B1 arenaviruses: Implications for receptor usage and pathogenicity
J Oldenburg et al.
Original research paper: Virology 364
doi:10.1016/j.virol.2007.03.003Ebola virus-like particle-induced activation of NF-κB and Erk signaling in human dendritic cells requires the glycoprotein mucin domain
O Martinez, C Valmas & C Basler
Original research paper: Virology 364
doi:10.1016/j.virol.2007.03.020An Emerging Role for Galectins in Tuning the Immune Response: Lessons from Experimental Models of Inflammatory Disease, Autoimmunity and Cancer
G. A. Rabinovich, F.-T. Liu, M. Hirashima & A. Anderson
Original research paper: Scandinavian Journal of Immunology 66
doi:10.1111/j.1365-3083.2007.01986.xExpression of oligodendrocyte myelin glycoprotein and its receptor NgR after the injury of rat central nervous system
Q Guo, S Li & B Su
Original research paper: Neuroscience Letters 422
doi:10.1016/j.neulet.2007.05.034Hepatitis C Virus Envelope Glycoprotein E2 Glycans Modulate Entry, CD81 Binding, and Neutralization
E. Falkowska et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00459-07The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein
F. Helle et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00127-07Identification of the Optimal DC-SIGN Binding Site on Human Immunodeficiency Virus Type 1 gp120
P. W.-P. Hong et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.01765-06Human Parainfluenza Viruses hPIV1 and hPIV3 Bind Oligosaccharides with 2-3-Linked Sialic Acids That Are Distinct from Those Bound by H5 Avian Influenza Virus Hemagglutinin
M. Amonsen, D. F. Smith, R. D. Cummings & G. M. Air
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00718-07N-Linked Glycosylation Attenuates H3N2 Influenza Viruses
D. J. Vigerust et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00769-07Induction of Calcium Influx through TRPC5 Channels by Cross-Linking of GM1 Ganglioside Associated with 5 1 Integrin Initiates Neurite Outgrowth
G. Wu et al.
Original research paper: Journal of Neuroscience 27
doi:10.1523/JNEUROSCI.4266-06.2007Rational proteomics of PKD1. I. Modeling the three dimensional structure and ligand specificity of the C_lectin binding domain of Polycystin-1.
Vladimir Pletnev et al.
Original research paper: Journal of Molecular Modeling 13
doi:10.1007/s00894-007-0201-zKinetics of mobilization and differentiation of lymphohematopoietic cells during experimental murine schistosomiasis in galectin-3 / mice
F. L. Oliveira et al.
Original research paper: Journal of Leukocyte Biology 82
doi:10.1189/jlb.1206747The 130-kDa Glycoform of CD43 Functions as an E-Selectin Ligand for Activated Th1 Cells In Vitro and in Delayed-Type Hypersensitivity Reactions In Vivo
Pilar Alcaide et al.
Original research paper: Journal of Investigative Dermatology 127
doi:10.1038/sj.jid.5700805Contribution of Glycosylation to T Cell Responses Stimulated by Recombinant Mannoprotein
Charles A. Specht et al.
Original research paper: The Journal of Infectious Diseases 196
doi:10.1086/520536Characterization of a novel modification on IgG2 light chain Evidence for the presence of O-linked mannosylation
T. Martinez et al.
Original research paper: Journal of Chromatography A 1156
doi:10.1016/j.chroma.2007.04.050Effects of mannosylated glycopolymers on specific interaction to bone marrow hematopoietic and progenitor cells derived from murine species
Keun-Hong Park et al.
Original research paper: Journal of Biomedical Materials Research Part A 82A
doi:10.1002/jbm.a.31137Lectin from Phaseolus acutifolius var. escumite: Chemical Characterization, Sugar Specificity, and Effect on Human T-Lymphocytes
A. Castillo-villanueva et al.
Original research paper: Journal of Agricultural and Food Chemistry 55
doi:10.1021/jf063644kRole of S128R polymorphism of E-selectin in colon metastasis formation
Riccardo Alessandro et al.
Original research paper: International Journal of Cancer 121
doi:10.1002/ijc.22693Heptose I Glycan Substitutions on Neisseria gonorrhoeae Lipooligosaccharide Influence C4b-Binding Protein Binding and Serum Resistance
S. Ram et al.
Original research paper: Infection and Immunity 75
doi:10.1128/IAI.01109-06Expression of hGC-1 is correlated with differentiation of gastric carcinoma
W Liu, J Zhu, L Cao & G P Rodgers
Original research paper: Histopathology 51
doi:10.1111/j.1365-2559.2007.02763.xPurification and characterisation of a natural lectin from the serum of the shrimp Litopenaeus vannamei
J Sun et al.
Original research paper: Fish & Shellfish Immunology 23
doi:10.1016/j.fsi.2006.11.001Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins
S Olivari & M Molinari
Original research paper: FEBS Letters 581
doi:10.1016/j.febslet.2007.04.070N-glycan structures and associated gene expression reflect the characteristic N-glycosylation pattern of human hematopoietic stem and progenitor cells
H Hemmoranta et al.
Original research paper: Experimental Hematology 35
doi:10.1016/j.exphem.2007.05.006Nanoscale Organization of the Pathogen Receptor DC-SIGN Mapped by Single-Molecule High-Resolution Fluorescence Microscopy
Bärbel I. De bakker et al.
Original research paper: ChemPhysChem 8
doi:10.1002/cphc.2007001691,2-Mannobioside Mimic: Synthesis, DC-SIGN Interaction by NMR and Docking, and Antiviral Activity
José J. Reina et al.
Original research paper: ChemMedChem 2
doi:10.1002/cmdc.200700047