Featured articles
Specially written reviews on the most exiting new findings in glycobiology. For Nature Group Publishing articles, free full access to the publication will be maintained for three months.
September 2007
Inflammation: Neutrophil integrins switched on by selectins
The interaction between P-selectin and P-selectin glycoprotein ligand-1 on neutrophils leads to integrin transactivation via phosphatidylinositol-3-OH kinase signaling and neutrophil accumulation at sites of inflammation.
Original research paper: Nature Immunology 8, 882-892 (2007)
doi:10.1038/ni1491Autommunity: Macrophages hunting mannose singles
Macrophage accumulation in the kidneys of systemic lupus erythematosus patients is caused by the presence of proteins possessing simplified N-glycan structures.
Original research paper: Immunity 27, 308-320 (2007)
doi:10.1016/j.immuni.2007.06.008