Research library: browse by date
From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. This library is a collection of the most significant research advances and key review articles in glycobiology from across the literature, spanning dates from 2006-2011.
September 2007
Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide
Giovanni D'angelo et al.
Original research paper: Nature 449 62-67 (2007)
doi:10.1038/nature06097Potentiation of Fibroblast Growth Factor Activity by Synthetic Heparin Oligosaccharide Glycodendrimers
J Depaz et al.
Original research paper: Chemistry & Biology 14
doi:10.1016/j.chembiol.2007.07.007Cooperativity in Glycan-Protein Interactions
R Raman & R Sasisekharan
Original research paper: Chemistry & Biology 14
doi:10.1016/j.chembiol.2007.08.003Innate Immune Response Triggers Lupus-like Autoimmune Disease
J Paulson
Original research paper: Cell 130
doi:10.1016/j.cell.2007.08.009Mammalian N-Glycan Branching Protects against Innate Immune Self-Recognition and Inflammation in Autoimmune Disease Pathogenesis
R Green et al.
Original research paper: Immunity 27
doi:10.1016/j.immuni.2007.06.008MyD88-mediated signals induce the bactericidal lectin RegIIIγ and protect mice against intestinal Listeria monocytogenes infection
K. Brandl et al.
Original research paper: Journal of Experimental Medicine 204
doi:10.1084/jem.20070563Synthesis and evaluation of stimulatory properties of Sphingomonadaceae glycolipids
Xiangtian Long et al.
Original research paper: Nature Chemical Biology 3 559-564 (2007)
doi:10.1038/nchembio.2007.19Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function
J. Kubach et al.
Original research paper: Blood 110
doi:10.1182/blood-2007-01-069229β2-Glycoprotein I inhibits von Willebrand factor dependent platelet adhesion and aggregation
J. J. J. Hulstein et al.
Original research paper: Blood 110
doi:10.1182/blood-2006-10-053199Galectin-1 mediated suppression of Epstein-Barr virus specific T-cell immunity in classic Hodgkin lymphoma
M. K. Gandhi et al.
Original research paper: Blood 110
doi:10.1182/blood-2007-01-066100A metabolic pathway leading to mannosylfructose biosynthesis in Agrobacterium tumefaciens uncovers a family of mannosyltransferases
L. L. Torres & G. L. Salerno
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0706709104Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma
A. Oldberg et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0702014104Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance
K. Kabayama et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0703650104A lymphocytic choriomeningitis virus glycoprotein variant that is retained in the endoplasmic reticulum efficiently cross-primes CD8+ T cell responses
S. Freigang et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0704423104Loss of T cell receptor-induced Bmi-1 in the KLRG1+ senescent CD8+ T lymphocyte
M. Heffner & D. T. Fearon
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0706040104The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphoma
P. Juszczynski et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0706017104Glycomics Analysis of Schistosoma mansoni Egg and Cercarial Secretions
J. Jang-lee et al.
Original research paper: Molecular & Cellular Proteomics 6
doi:10.1074/mcp.M700004-MCP200Ligand Specificity of CS-35, a Monoclonal Antibody That Recognizes Mycobacterial Lipoarabinomannan: A Model System for Oligofuranoside-Protein Recognition
C. Rademacher et al.
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja0723380Understanding endothelial cell apoptosis: what can the transcriptome, glycome and proteome reveal?
Muna Affara et al.
Original research paper: Philosophical Transactions of the Royal Society B: Biological Sciences 362
doi:10.1098/rstb.2007.2129Comparative Glycomic Mapping through Quantitative Permethylation and Stable-Isotope Labeling
P. Kang et al.
Original research paper: Analytical Chemistry 79
doi:10.1021/ac062098rOn-Line HPLC/ESI-MS Separation and Characterization of Hyaluronan Oligosaccharides from 2-mers to 40-mers
N. Volpi
Original research paper: Analytical Chemistry 79
doi:10.1021/ac070837dTumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells
C. Napoletano et al.
Original research paper: Cancer Research 67
doi:10.1158/0008-5472.CAN-07-1035Phosphoinositide 3-kinase is activated by MUC1 but not responsible for MUC1-induced suppression of Toll-like receptor 5 signaling
K. Kato, W. Lu, H. Kai & K. C. Kim
Original research paper: AJP: Lung Cellular and Molecular Physiology 293
doi:10.1152/ajplung.00423.2006Biological and therapeutic significance of MUC1 with sialoglycans in clear cell adenocarcinoma of the ovary
Yutaka Tamada et al.
Original research paper: Cancer Science 98
doi:10.1111/j.1349-7006.2007.00582.xPurification and characterization of 66-kDa glycoprotein from human breast carcinoma
Renqing Feng, Xiang Liu, Zhenquan Guo & Jinfeng Li
Original research paper: Cancer Science 98
doi:10.1111/j.1349-7006.2007.00539.xThe Inhibition Site on Myelin-Associated Glycoprotein Is within Ig-Domain 5 and Is Distinct from the Sialic Acid Binding Site
Z. Cao et al.
Original research paper: Journal of Neuroscience 27
doi:10.1523/JNEUROSCI.2404-07.2007Transforming Growth Factor β1-regulated Xylosyltransferase I Activity in Human Cardiac Fibroblasts and Its Impact for Myocardial Remodeling
C. Prante et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702299200Polysialylation Increases Lateral Diffusion of Neural Cell Adhesion Molecule in the Cell Membrane
F. Conchonaud et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M608590200Translocation of Activated Heterotrimeric G Protein Gαo to Ganglioside-enriched Detergent-resistant Membrane Rafts in Developing Cerebellum
K. Yuyama, N. Sekino-suzuki, Y. Sanai & K. Kasahara
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M705046200The Insulin-like Growth Factor Type 1 and Insulin-like Growth Factor Type 2/Mannose-6-phosphate Receptors Independently Regulate ERK1/2 Activity in HEK293 Cells
H. M. El-shewy et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M703276200Involvement of the Snake Toxin Receptor CLEC-2, in Podoplanin-mediated Platelet Activation, by Cancer Cells
K. Suzuki-inoue et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702327200Potential Role for Heparan Sulfate Proteoglycans in Regulation of Transforming Growth Factor-β (TGF-β) by Modulating Assembly of Latent TGF-β-binding Protein-1
Q. Chen et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M703341200Involvement of Hyaluronan in Regulation of Fibroblast Phenotype
S. Meran et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M700773200Binding of ADAM28 to P-selectin Glycoprotein Ligand-1 Enhances P-selectin-mediated Leukocyte Adhesion to Endothelial Cells
M. Shimoda et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702414200Site-specific Fucosylation of Sialylated Polylactosamines by α1,3/4-Fucosyltransferases-V and -VI Is Defined by Amino Acids Near the N Terminus of the Catalytic Domain
S. Shetterly et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702395200The Heparin/Heparan Sulfate Sequence That Interacts with Cyclophilin B Contains a 3-O-Sulfated N-Unsubstituted Glucosamine Residue
C. Vanpouille et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M701835200Structural Basis of Sterol Binding by NPC2, a Lysosomal Protein Deficient in Niemann-Pick Type C2 Disease
S. Xu et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M703848200Paratope and Epitope Mapping of the Antithrombotic Antibody 6B4 in Complex with Platelet Glycoprotein Ibα
A. Fontayne et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M701826200Interdomain Interaction in the FimH Adhesin of Escherichia coli Regulates the Affinity to Mannose
P. Aprikian et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M702037200Systems Analysis of N-Glycan Processing in Mammalian Cells
Patrick Hossler, Bhanu Chandra Mulukutla, Wei-Shou Hu & Mariko Hatakeyama
Original research paper: PLoS ONE 2
doi:10.1371/journal.pone.0000713CD83 Modulates B Cell Function In Vitro: Increased IL-10 and Reduced Ig Secretion by CD83Tg B Cells
Birte Kretschmer et al.
Original research paper: PLoS ONE 2
doi:10.1371/journal.pone.0000755Sialic acid utilization by bacterial pathogens
E. Severi, D. W. Hood & G. H. Thomas
Original research paper: Microbiology 153
doi:10.1099/mic.0.2007/009480-0Biochemical characterization of a Neisseria meningitidis polysialyltransferase reveals novel functional motifs in bacterial sialyltransferases
Friedrich Freiberger et al.
Original research paper: Molecular Microbiology 65
doi:10.1111/j.1365-2958.2007.05862.xInhibition of Mammalian Glycan Biosynthesis Produces Non-self Antigens for a Broadly Neutralising, HIV-1 Specific Antibody
C Scanlan et al.
Original research paper: Journal of Molecular Biology 372
doi:10.1016/j.jmb.2007.06.027The Structures of Bacteriophages K1E and K1-5 Explain Processive Degradation of Polysaccharide Capsules and Evolution of New Host Specificities
P Leiman et al.
Original research paper: Journal of Molecular Biology 371
doi:10.1016/j.jmb.2007.05.083Role of the Cytoplasmic Tail Domains of Bunyamwera Orthobunyavirus Glycoproteins Gn and Gc in Virus Assembly and Morphogenesis
X. Shi, A. Kohl, P. Li & R. M. Elliott
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00573-07Immunogenicity of Influenza Virus Vaccine Is Increased by Anti-Gal-Mediated Targeting to Antigen-Presenting Cells
U. M. Abdel-motal et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00647-07Binding-Site Interactions between Epstein-Barr Virus Fusion Proteins gp42 and gH/gL Reveal a Peptide That Inhibits both Epithelial and B-Cell Membrane Fusion
A. N. Kirschner, A. S. Lowrey, R. Longnecker & T. S. Jardetzky
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00575-07Expression and Characterization of a Minimal Hepatitis C Virus Glycoprotein E2 Core Domain That Retains CD81 Binding
K. Mccaffrey, I. Boo, P. Poumbourios & H. E. Drummer
Original research paper: Journal of Virology 81
doi:10.1128/JVI.02782-06Porcine Arterivirus Attachment to the Macrophage-Specific Receptor Sialoadhesin Is Dependent on the Sialic Acid-Binding Activity of the N-Terminal Immunoglobulin Domain of Sialoadhesin
P. L. Delputte et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00569-07Hydrophobic Residues That Form Putative Fusion Loops of Epstein-Barr Virus Glycoprotein B Are Critical for Fusion Activity
M. Backovic, T. S. Jardetzky & R. Longnecker
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00758-07Characterization of the interaction between von Willebrand factor and osteoprotegerin
S. Shahbazi et al.
Original research paper: Journal of Thrombosis and Haemostasis 5
doi:10.1111/j.1538-7836.2007.02681.xNormal cellular prion protein is a ligand of selectins: binding requires LeX but is inhibited by sLeX
Chaoyang Li et al.
Original research paper: Biochemical Journal 406
doi:10.1042/BJ20061857Glycolipid Membranes through Atomistic Simulations: Effect of Glucose and Galactose Head Groups on Lipid Bilayer Properties
T. Rog, I. Vattulainen, A. Bunker & M. Karttunen
Original research paper: Journal of Physical Chemistry B 111
doi:10.1021/jp0730895Ectodomain shedding of neuroglycan C, a brain-specific chondroitin sulfate proteoglycan, by TIMP-2- and TIMP-3-sensitive proteolysis
Takuya Shuo et al.
Original research paper: Journal of Neurochemistry 102
doi:10.1111/j.1471-4159.2007.04658.xN-Glycosylation regulates endothelial lipase-mediated phospholipid hydrolysis in apoE- and apoA-I-containing high density lipoproteins
D. Skropeta et al.
Original research paper: The Journal of Lipid Research 48
doi:10.1194/jlr.M700248-JLR200Endothelial selectins regulate skin wound healing in cooperation with L-selectin and ICAM-1
T. Yukami et al.
Original research paper: Journal of Leukocyte Biology 82
doi:10.1189/jlb.0307152Mannose receptor regulation of macrophage cell migration
J. Sturge et al.
Original research paper: Journal of Leukocyte Biology 82
doi:10.1189/jlb.0107053Homo- and Heterotypic Cell Contacts in Malignant Melanoma Cells and Desmoglein 2 as a Novel Solitary Surface Glycoprotein
Christian J Schmitt et al.
Original research paper: Journal of Investigative Dermatology 127 2191-2206 (2007)
doi:10.1038/sj.jid.5700849Contribution of Glycosylation to T Cell Responses Stimulated by Recombinant Mannoprotein
Charles A. Specht et al.
Original research paper: The Journal of Infectious Diseases 196
doi:10.1086/520536The metabolism and function of sphingolipids and glycosphingolipids
S. Lahiri & A. H. Futerman
Original research paper: Cellular and Molecular Life Sciences 64
doi:10.1007/s00018-007-7076-0A trisulfide-linked glycoprotein
Gonçalo J. L. Bernardes et al.
Original research paper: Chemical Communications
doi:10.1039/b706682aAnti-Carbohydrate Antibodies Elicited by Polyvalent Display on a Viral Scaffold
Eiton Kaltgrad et al.
Original research paper: ChemBioChem 8
doi:10.1002/cbic.200700225Mannan and peptidoglycan induce COX-2 protein in human PMNvia the mammalian target of rapamycin
Nieves Fernández et al.
Original research paper: European Journal of Immunology 37
doi:10.1002/eji.200737262Association of deficiency for mannan-binding lectin with anti-mannan antibodies in Crohn's disease: A family study
Frank Seibold et al.
Original research paper: Inflammatory Bowel Diseases 13
doi:10.1002/ibd.20156Identification of Histidine-Rich Glycoprotein, a Potential Autoantigen, in Human and Rat Brain Preparations
C. Ball-rosen et al.
Original research paper: Annals of the New York Academy of Sciences 1109
doi:10.1196/annals.1398.053P-Glycoprotein is not present in mitochondrial membranes
J Paterson & M Gottesman
Original research paper: Experimental Cell Research 313
doi:10.1016/j.yexcr.2007.04.019Glycoprotein E (gE) specified by bovine herpesvirus type 5 (BHV-5) enables trans-neuronal virus spread and neurovirulence without being a structural component of enveloped virions
A Almubarak et al.
Original research paper: Virology 365
doi:10.1016/j.virol.2007.03.040The role of the downstream signal sequences in the maturation of the HBV middle surface glycoprotein: Development of a novel therapeutic vaccine candidate
Y Liu et al.
Original research paper: Virology 365
doi:10.1016/j.virol.2007.03.042Epitope mapping of HSV-1 glycoprotein K (gK) reveals a T cell epitope located within the signal domain of gK
Y Osorio et al.
Original research paper: Virus Research 128
doi:10.1016/j.virusres.2007.04.007Deletion of N-glycosylation sites of hepatitis C virus envelope protein E1 enhances specific cellular and humoral immune responses
M Liu et al.
Original research paper: Vaccine 25
doi:10.1016/j.vaccine.2007.07.003Generation of blood group specificity: New insights from structural studies on the complexes of A- and B-reactive saccharides with basic winged bean agglutinin
Kiran A. Kulkarni et al.
Original research paper: Proteins: Structure, Function, and Bioinformatics 68
doi:10.1002/prot.21428Production of a monoclonal antibody in plants with a humanized N-glycosylation pattern
Matthias Schähs et al.
Original research paper: Plant Biotechnology Journal 5
doi:10.1111/j.1467-7652.2007.00273.xGalectins – Potential targets for cancer therapy
S Hasan, G Ashraf & N Banu
Original research paper: Cancer Letters 253
doi:10.1016/j.canlet.2006.11.030Antibody therapeutics:
Roy Jefferis
Original research paper: Expert Opinion on Biological Therapy 7
doi:10.1517/14712598.7.9.1401Differential sialylation regulates the apoptotic activity of glycodelin A
B Poornima & A Karande
Original research paper: FEBS Letters 581
doi:10.1016/j.febslet.2007.07.078Distribution of the glycoconjugate oligosaccharides in the human placenta from pregnancies complicated by altered glycemia: lectin histochemistry
Eleonora Sgambati et al.
Original research paper: Histochemistry and Cell Biology 128
doi:10.1007/s00418-007-0312-8The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma
B Van der vegt et al.
Original research paper: Histopathology 51
doi:10.1111/j.1365-2559.2007.02757.xThe BclB Glycoprotein of Bacillus anthracis Is Involved in Exosporium Integrity
B. M. Thompson et al.
Original research paper: Journal of Bacteriology 189
doi:10.1128/JB.00762-07Protein Glycosylation in Campylobacter jejuni: Partial Suppression of pglF by Mutation of pseC
P. Guerry, C. P. Ewing, I. C. Schoenhofen & S. M. Logan
Original research paper: Journal of Bacteriology 189
doi:10.1128/JB.00642-07Recent advances in the glycosylation of sphingosines and ceramides
J Moralesserna et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2007.03.028Synthesis of galactose-mimicking 1H-(1,2,3-triazol-1-yl)-mannosides as selective galectin-3 and 9N inhibitors
J Tejler, F Skogman, H Leffler & U Nilsson
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2007.03.012The O-specific polysaccharide structure from the lipopolysaccharide of the Gram-negative bacterium Raoultella terrigena
S Leone et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2007.04.012Synthesis of CMP-9"-modified-sialic acids as donor substrate analogues for mammalian and bacterial sialyltransferases
Y Kajihara et al.
Original research paper: Carbohydrate Research 342
doi:10.1016/j.carres.2007.05.029Cloning, expression and characterization of two C-type lectins from the venom gland of Bungarus multicinctus
L Lin, Q Lin & Y Wang
Original research paper: Toxicon 50
doi:10.1016/j.toxicon.2007.04.019Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle
E Keyaerts et al.
Original research paper: Antiviral Research 75
doi:10.1016/j.antiviral.2007.03.003Analysis of ER-associated glycoprotein degradation using synthetic glycopeptide probes
S Hagihara, K Goda, I Matsuo & Y Ito
Original research paper: Biochemical and Biophysical Research Communications 360
doi:10.1016/j.bbrc.2007.06.053Purification and characterization of lectin from fruiting body of Ganoderma lucidumLectin from Ganoderma lucidum
A Thakur et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - General Subjects 1770
doi:10.1016/j.bbagen.2007.05.009Identification of proteins bearing β1–6 branched N-glycans in human melanoma cell lines from different progression stages by tandem mass spectrometry analysis
M Przybylo et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - General Subjects 1770
doi:10.1016/j.bbagen.2007.05.006Glycoprotein-surfactant interactions: A calorimetric and spectroscopic investigation of the phytase-SDS system
H Bagger, S Hoffmann, C Fuglsang & P Westh
Original research paper: Biophysical Chemistry 129
doi:10.1016/j.bpc.2007.06.005Bone sialoprotein expression enhances osteoblast differentiation and matrix mineralization in vitro
J Gordon et al.
Original research paper: Bone 41
doi:10.1016/j.bone.2007.04.191Human soluble E-selectin immunoadhesin inhibits leukemic monocyte adhesion to endothelial cells
Bong Hwan Sung et al.
Original research paper: Cell Biochemistry and Function 25
doi:10.1002/cbf.1361P-glycoprotein expression in extracellular matrix formation of chondrogenic differentiation of human adult stem cells
S Kim et al.
Original research paper: Cell Biology International 31
doi:10.1016/j.cellbi.2007.03.018Influence of N-Glycosylation on Saccharomyces cerevisiae Morphology: A Golgi Glycosylation Mutant Shows Cell Division Defects
Jungang Zhou et al.
Original research paper: Current Microbiology 55
doi:10.1007/s00284-006-0585-5Potential tumor markers for human gastric cancer: an elevation of glycan:sulfotransferases and a concomitant loss of α1,2-fucosyltransferase activities
E. V. Chandrasekaran et al.
Original research paper: Journal of Cancer Research and Clinical Oncology 133
doi:10.1007/s00432-007-0206-0Analysing protein–protein interaction networks of human liver cancer cell lines with diverse metastasis potential
Hai-jun Zhou et al.
Original research paper: Journal of Cancer Research and Clinical Oncology 133
doi:10.1007/s00432-007-0218-9Interaction of MUC1 with β-catenin modulates the Wnt target Gene cyclinD1 inH.pylori-induced gastric cancer
Gopal Udhayakumar, Venkatraman Jayanthi, Niranjali Devaraj & Halagowder Devaraj
Original research paper: Molecular Carcinogenesis 46
doi:10.1002/mc.20311Variations of ganglioside biosynthetic pathways in the phenotype conversion from myofibroblasts to lipocytes in murine hepatic stellate cell line
Aline B. Aguirres et al.
Original research paper: Molecular and Cellular Biochemistry 303
doi:10.1007/s11010-007-9464-z
