Featured articles
Specially written reviews on the most exiting new findings in glycobiology. For Nature Group Publishing articles, free full access to the publication will be maintained for three months.
October 2007
Apoptosis: A GALNT death
O-glycosylation enhances tumor cell sensitivity to apoptosis by promoting clustering of the death receptors DR4 and DR5 by their ligand Apo2L/TRAIL, thereby providing a valuable biomarker for apoptosis-based cancer therapies.
Original research paper: Nature Medicine 13, 1070-1077 (2007)
doi:10.1038/nm1627Glycolipid immunology: How to hide in a surveillance society
A germline-encoded cluster of amino acid residues enables recognition of diverse microbial glycosphingolipids (GSL), yet bacteria can escape from immunorecognition by synthesis of oligosaccharidic GSL head groups.
Original research paper: Nature Chemical Biology 3, 559-564 (2007)
doi:10.1038/nchembio.2007.19