Functional Glycomics homepage

Featured articles

From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. Here, access the complete archive of Featured Articles, specially written editors' reviews on the most exciting findings in glycobiology. Original pieces created by NPG as part of the NPG-CFG partnership are subject to copyright by the Nature Publishing Group, a division of Macmillan Publishers Limited; used with permission.

  • October 2007

    • Apoptosis: A GALNT death

      O-glycosylation enhances tumor cell sensitivity to apoptosis by promoting clustering of the death receptors DR4 and DR5 by their ligand Apo2L/TRAIL, thereby providing a valuable biomarker for apoptosis-based cancer therapies.

      Original research paper: Nature Medicine 13, 1070-1077 (2007)
      doi:10.1038/nm1627

    • Glycolipid immunology: How to hide in a surveillance society

      A germline-encoded cluster of amino acid residues enables recognition of diverse microbial glycosphingolipids (GSL), yet bacteria can escape from immunorecognition by synthesis of oligosaccharidic GSL head groups.

      Original research paper: Nature Chemical Biology 3, 559-564 (2007)
      doi:10.1038/nchembio.2007.19

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