Research library: browse by date
The Research Library categorizes and provides access to all recent glycobiology-related research published by Nature Publishing Group and other journals. The selection is deliberately broad to facilitate access to all research impacting on the glycobiology community. Both primary research and review articles are included.
October 2007
The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy
Y. Yang et al.
Original research paper: Blood 110
doi:10.1182/blood-2007-04-082495The MUC1 and Galectin-3 Oncoproteins Function in a MicroRNA-Dependent Regulatory Loop
S Ramasamy et al.
Original research paper: Molecular Cell 27
doi:10.1016/j.molcel.2007.07.031Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs
D. E. Willis et al.
Original research paper: The Journal of Cell Biology 178
doi:10.1083/jcb.200703209Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4
C.-c. Huang et al.
Original research paper: Science 317
doi:10.1126/science.1145373Structural basis for complement factor H linked age-related macular degeneration
B. E. Prosser et al.
Original research paper: Journal of Experimental Medicine 204
doi:10.1084/jem.20071069The novel AML stem cell associated antigen CLL-1 aids in discrimination between normal and leukemic stem cells
A. Van Rhenen et al.
Original research paper: Blood 110
doi:10.1182/blood-2007-03-083048The oxidase activity of vascular adhesion protein-1 (VAP-1) induces endothelial E- and P-selectins and leukocyte binding
S. Jalkanen et al.
Original research paper: Blood 110
doi:10.1182/blood-2007-01-069674Trousseau's syndrome: multiple definitions and multiple mechanisms
A. Varki
Original research paper: Blood 110
doi:10.1182/blood-2006-10-053736Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype
Eugene A Podrez et al.
Original research paper: Nature Medicine 13 1086-1095 (2007)
doi:10.1038/nm1626Death-receptor O-glycosylation controls tumor-cell sensitivity to the proapoptotic ligand Apo2L/TRAIL
Klaus W Wagner et al.
Original research paper: Nature Medicine 13 1070-1077 (2007)
doi:10.1038/nm1627Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution
Gavin J Williams, Changsheng Zhang & Jon S Thorson
Original research paper: Nature Chemical Biology 3 657-662 (2007)
doi:10.1038/nchembio.2007.28Robust immune responses elicited by a fully synthetic three-component vaccine
Sampat Ingale et al.
Original research paper: Nature Chemical Biology 3 663-667 (2007)
doi:10.1038/nchembio.2007.25Recent advances in antigen processing and presentation
Peter E Jensen
Original research paper: Nature Immunology 8 1041-1048 (2007)
doi:10.1038/ni1516Germline-encoded recognition of diverse glycolipids by natural killer T cells
James P Scott-Browne et al.
Original research paper: Nature Immunology (2007)
doi:10.1038/ni1510Lung Cancer Survival and Functional Polymorphisms in MBL2, an Innate-Immunity Gene
S. R. Pine et al.
Original research paper: JNCI Journal of the National Cancer Institute 99
doi:10.1093/jnci/djm128Polylactosamine on glycoproteins influences basal levels of lymphocyte and macrophage activation
A. Togayachi et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0707426104Plasmodium falciparum ookinetes require mosquito midgut chondroitin sulfate proteoglycans for cell invasion
R. R. Dinglasan et al.
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0706340104Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis
Tiziana Anelli et al.
Original research paper: The EMBO Journal 26
doi:10.1038/sj.emboj.7601844Evolutionary vignettes of natural killer cell receptors
J Sambrook & S Beck
Original research paper: Current Opinion in Immunology 19
doi:10.1016/j.coi.2007.08.002Exploring the Sialiome Using Titanium Dioxide Chromatography and Mass Spectrometry
M. R. Larsen, S. S. Jensen, L. A. Jakobsen & N. H. H. Heegaard
Original research paper: Molecular & Cellular Proteomics 6
doi:10.1074/mcp.M700086-MCP200Apoptotic Killing of HIV-1–Infected Macrophages Is Subverted by the Viral Envelope Glycoprotein
Simon Swingler et al.
Original research paper: PLoS Pathogens 3
doi:10.1371/journal.ppat.0030134Regulation of the Extrinsic Apoptotic Pathway by the Extracellular Matrix Glycoprotein EMILIN2
M. Mongiat et al.
Original research paper: Molecular and Cellular Biology 27
doi:10.1128/MCB.00696-07Polysialic Acid-Directed Migration and Differentiation of Neural Precursors Are Essential for Mouse Brain Development
K. Angata et al.
Original research paper: Molecular and Cellular Biology 27
doi:10.1128/MCB.00205-07Refining genotype phenotype correlations in muscular dystrophies with defective glycosylation of dystroglycan
C. Godfrey et al.
Original research paper: Brain 130
doi:10.1093/brain/awm212New POMT2 mutations causing congenital muscular dystrophy: Identification of a founder mutation
A. Yanagisawa et al.
Original research paper: Neurology 69
doi:10.1212/01.wnl.0000268489.60809.c4Synthetic Analogues of Glycosylphosphatidylinositol-Anchored Proteins and Their Behavior in Supported Lipid Bilayers
M.G. Paulick et al.
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja073271jQuantitative Analysis of Carbohydrate-Protein Interactions Using Glycan Microarrays: Determination of Surface and Solution Dissociation Constants
P.-H. Liang, S.-K. Wang & C.-H. Wong
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja072931hGoing to Extremes: "Super" Armed Glycosyl Donors in Glycosylation Chemistry
Henrik, H. Jensen, Christian, Marcus Pedersen, Mikael Bols
Original research paper: Chemistry - A European Journal 13
doi:10.1002/chem.200700947Stability of Soluble Adhesion Molecules, Selectins, and C-Reactive Protein at Various Temperatures: Implications for Epidemiological and Large-Scale Clinical Studies
J. Hartweg et al.
Original research paper: Clinical Chemistry 53
doi:10.1373/clinchem.2006.076380GLYCO 19 International Symposium on Glycoconjugates: Abstracts
Original research paper: Glycoconjugate Journal 24
doi:10.1007/s10719-007-9057-9Binding Activities and Antitumor Properties of a New Mouse/Human Chimeric Antibody Specific for GD2 Ganglioside Antigen
N. Alvarez-Rueda et al.
Original research paper: Clinical Cancer Research 13
doi:10.1158/1078-0432.CCR-07-1057Membrane Topology of the Alg14 Endoplasmic Reticulum UDP-GlcNAc Transferase Subunit
N. Averbeck, S. Keppler-ross & N. Dean
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704410200Contributions of Galectin-3 and -9 to Epithelial Cell Adhesion Analyzed by Single Cell Force Spectroscopy
J. Friedrichs et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M701867200The de Novo Synthesis of GDP-fucose Is Essential for Flagellar Adhesion and Cell Growth in Trypanosoma brucei
D. C. Turnock, L. Izquierdo & M. A. J. Ferguson
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704742200Role of Glycosylation in Corin Zymogen Activation
X. Liao, W. Wang, S. Chen & Q. Wu
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M703687200Sequential Action of Ets-1 and Sp1 in the Activation of the Human beta-1,4-Galactosyltransferase V Gene Involved in Abnormal Glycosylation Characteristic of Cancer Cells
T. Sato & K. Furukawa
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M611862200Structural Basis for Recognition of High Mannose Type Glycoproteins by Mammalian Transport Lectin VIP36
T. Satoh et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M703064200Binding Studies of α-GalNAc-specific Lectins to the α-GalNAc (Tn-antigen) Form of Porcine Submaxillary Mucin and Its Smaller Fragments
T. K. Dam et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704677200NeuA Sialic Acid O-Acetylesterase Activity Modulates O-Acetylation of Capsular Polysaccharide in Group B Streptococcus
A. L. Lewis et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M700340200β2-Integrins and Acquired Glycoprotein IIb/IIIa (GPIIb/IIIa) Receptors Cooperate in NF-κB Activation of Human Neutrophils
B. Salanova et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704039200Gangliosides and Nogo Receptors Independently Mediate Myelin-associated Glycoprotein Inhibition of Neurite Outgrowth in Different Nerve Cells
N. R. Mehta, P. H. H. Lopez, A. A. Vyas & R. L. Schnaar
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704055200Glucosamine Hydrochloride Specifically Inhibits COX-2 by Preventing COX-2 N-Glycosylation and by Increasing COX-2 Protein Turnover in a Proteasome-dependent Manner
B.-C. Jang et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M610778200Aegyptin, a Novel Mosquito Salivary Gland Protein, Specifically Binds to Collagen and Prevents Its Interaction with Platelet Glycoprotein VI, Integrin α2β1, and von Willebrand Factor
E. Calvo et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M705669200Dislocation of an Endoplasmic Reticulum Membrane Glycoprotein Involves the Formation of Partially Dislocated Ubiquitinated Polypeptides
B. M. Baker & D. Tortorella
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704315200Glycosyltransferases Involved in Biosynthesis of the Outer Core Region of Escherichia coli Lipopolysaccharides Exhibit Broader Substrate Specificities Than Is Predicted from Lipopolysaccharide Structures
M. D. Leipold, E. Vinogradov & C. Whitfield
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M704131200αvβ5 Integrin Sustains Growth of Human Pre-B Cells through an RGD-independent Interaction with a Basic Domain of the CD23 Protein
G. Borland et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M609335200Regulation of sialic acid transport and catabolism in Haemophilus influenzae
Jason W. Johnston et al.
Original research paper: Molecular Microbiology 66
doi:10.1111/j.1365-2958.2007.05890.xAntibody GD3G7 Selected against Embryonic Glycosaminoglycans Defines Chondroitin Sulfate-E Domains Highly Up-Regulated in Ovarian Cancer and Involved in Vascular Endothelial Growth Factor Binding
G. B. Ten dam et al.
Original research paper: American Journal Of Pathology 171
doi:10.2353/ajpath.2007.070111Inhibition of Wnt-2 and galectin-3 synergistically destabilizes β-catenin and induces apoptosis in human colorectal cancer cells
Yihui Shi et al.
Original research paper: International Journal of Cancer 121
doi:10.1002/ijc.22848Lentiviral-mediated Expression of Polysialic Acid in Spinal Cord and Conditioning Lesion Promote Regeneration of Sensory Axons Into Spinal Cord
Yi Zhang et al.
Original research paper: Molecular Therapy 15 1796-1804 (2007)
doi:10.1038/sj.mt.6300220Host Single-Nucleotide Polymorphisms and Altered Responses to Inactivated Influenza Vaccine
Yi-Wei Tang et al.
Original research paper: The Journal of Infectious Diseases 196
doi:10.1086/521370The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor
Thomas Kroslak et al.
Original research paper: Journal of Neurochemistry 0
doi:10.1111/j.1471-4159.2007.04738.xCharacterization of Oligo- and Polysialic Acids by MALDI-TOF-MS
S.P. Galuska, R. Geyer, M. Muhlenhoff & H. Geyer
Original research paper: Analytical Chemistry 79
doi:10.1021/ac0712446Photoderivatized Polymer Thin Films at Quartz Crystal Microbalance Surfaces: Sensors for Carbohydrate-Protein Interactions
Y. Pei et al.
Original research paper: Analytical Chemistry 79
doi:10.1021/ac070740rElectrophoretic Analysis of N-Glycans on Microfluidic Devices
Z. Zhuang et al.
Original research paper: Analytical Chemistry 79
doi:10.1021/ac071261vLabel-Free Impedimetric Detection of Glycan-Lectin Interactions
J.T. Labelle, J.Q. Gerlach, S. Svarovsky & L. Joshi
Original research paper: Analytical Chemistry 79
doi:10.1021/ac070651eN-Glycosylation of the Human κ Opioid Receptor Enhances Its Stability but Slows Its Trafficking along the Biosynthesis Pathway
J.-G. Li, C. Chen & L.-Y. Liu-chen
Original research paper: Biochemistry 46
doi:10.1021/bi700443jStructure-Activity Relationships in the Binding of Chemically Derivatized CD4 to gp120 from Human Immunodeficiency Virus
H. Xie et al.
Original research paper: Journal of Medicinal Chemistry 50
doi:10.1021/jm070564eInhibition of Mammalian Glycan Biosynthesis Produces Non-self Antigens for a Broadly Neutralising, HIV-1 Specific Antibody
C Scanlan et al.
Original research paper: Journal of Molecular Biology 372
doi:10.1016/j.jmb.2007.06.027Structure and Action of the C–C Bond-forming Glycosyltransferase UrdGT2 Involved in the Biosynthesis of the Antibiotic Urdamycin
M Mittler, A Bechthold & G Schulz
Original research paper: Journal of Molecular Biology 372
doi:10.1016/j.jmb.2007.06.005Up-regulation of leukocyte CXCR4 expression by sulfatide: An L-selectin-dependent pathway on CD4+ T cells
Pascal Duchesneau, Erin Gallagher, Bruce Walcheck & Thomas K. Waddell
Original research paper: European Journal of Immunology 37
doi:10.1002/eji.200737118Conservation of IL-6 trans-signaling mechanisms controlling L-selectin adhesion by fever-range thermal stress
Michelle M. Appenheimer et al.
Original research paper: European Journal of Immunology 37
doi:10.1002/eji.200636421Interaction of β2-Glycoprotein 1 with Phosphatidylserine-Containing Membranes: Ligand-Dependent Conformational Alterations Initiate Bivalent Binding
R. Hamdan, S.N. Maiti & A.J. Schroit
Original research paper: Biochemistry 46
doi:10.1021/bi700621jGlycosidase inhibitors as conformational transition state analogues
Ian R. Greig & Ian H. Williams
Original research paper: Chemical Communications
doi:10.1039/b705607aShort-Range Structure of a GM3 Ganglioside Membrane: Comparison between Experimental WAXS and Computer Simulation Results
M. Sega et al.
Original research paper: Journal of Physical Chemistry B 111
doi:10.1021/jp072834aAminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3
E Yang et al.
Original research paper: Biochemical and Biophysical Research Communications 363
doi:10.1016/j.bbrc.2007.08.179NG2 proteoglycan increases mesangial cell proliferation and extracellular matrix production
J Xiong et al.
Original research paper: Biochemical and Biophysical Research Communications 361
doi:10.1016/j.bbrc.2007.07.113De-N-glycosylation or G82S mutation of RAGE sensitizes its interaction with advanced glycation endproducts
M Osawa et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - General Subjects 1770
doi:10.1016/j.bbagen.2007.07.003Purification of the receptor for the N-acetyl-d-glucosamine specific adhesin of Mannheimia haemolytica from bovine neutrophils
A Delamora et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - General Subjects 1770
doi:10.1016/j.bbagen.2007.07.006Importance of N-glycosylation positioning for secretion and folding of ovalbumin
K Ito, T Ishimaru, F Kimura & N Matsudomi
Original research paper: Biochemical and Biophysical Research Communications 361
doi:10.1016/j.bbrc.2007.07.066Involvement of glycan chains in the antigenicity of Rapana thomasiana hemocyanin
N Siddiqui et al.
Original research paper: Biochemical and Biophysical Research Communications 361
doi:10.1016/j.bbrc.2007.07.098Synthetic glycan ligand excludes CD22 from antigen receptor-containing lipid rafts
J Yu et al.
Original research paper: Biochemical and Biophysical Research Communications 360
doi:10.1016/j.bbrc.2007.06.110Role of 3-O-sulfated heparan sulfate in virus-induced polykaryocyte formation
V Tiwari et al.
Original research paper: FEBS Letters 581
doi:10.1016/j.febslet.2007.08.029A Glycomics Platform for the Analysis of Permethylated Oligosaccharide Alditols
C Costello, J Contadomiller & J Cipollo
Original research paper: Journal of the American Society for Mass Spectrometry 18
doi:10.1016/j.jasms.2007.07.016Discrimination of 16 Structural Isomers of Fucosyl Galactoside Based on Energy-Resolved Mass Spectrometry
S Daikoku et al.
Original research paper: Journal of the American Society for Mass Spectrometry 18
doi:10.1016/j.jasms.2007.07.021Complexes between Herpes Simplex Virus Glycoproteins gD, gB, and gH Detected in Cells by Complementation of Split Enhanced Green Fluorescent Protein
E. Avitabile, C. Forghieri & G. Campadelli-fiume
Original research paper: Journal of Virology 81
doi:10.1128/JVI.01343-07Incorporation of High Levels of Chimeric Human Immunodeficiency Virus Envelope Glycoproteins into Virus-Like Particles
B.-Z. Wang et al.
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00542-07The Cytoplasmic Tails of Uukuniemi Virus (Bunyaviridae) GN and GC Glycoproteins Are Important for Intracellular Targeting and the Budding of Virus-Like Particles
A. K. Overby, V. L. Popov, R. F. Pettersson & E. P. A. Neve
Original research paper: Journal of Virology 81
doi:10.1128/JVI.00767-07Incorporation of Functional HN-F Glycoprotein-Containing Complexes into Newcastle Disease Virus Is Dependent on Cholesterol and Membrane Lipid Raft Integrity
J. P. Laliberte, L. W. Mcginnes & T. G. Morrison
Original research paper: Journal of Virology 81
doi:10.1128/JVI.01119-07N-Linked Glycan Modifications in gp120 of Human Immunodeficiency Virus Type 1 Subtype C Render Partial Sensitivity to 2G12 Antibody Neutralization
E. S. Gray, P. L. Moore, R. A. Pantophlet & L. Morris
Original research paper: Journal of Virology 81
doi:10.1128/JVI.01106-07Post-translational modifications of Epstein Barr virus BARF1 oncogene-encoded polypeptide
M. De Turenne-Tessier & T. Ooka
Original research paper: Journal of General Virology 88
doi:10.1099/vir.0.83058-0Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of DsrEFH from
Christiane Dahl, Andrea Schulte & Dong Hae Shin
Original research paper: Acta Crystallographica Section F Structural Biology and Crystallization Communications 63
doi:10.1107/S1744309107041188Analysis of N-glycan in serum glycoproteins from db/db mice and humans with type 2 diabetes
N. Itoh et al.
Original research paper: AJP: Endocrinology and Metabolism 293
doi:10.1152/ajpendo.00182.2007Knockout of the gene (ste15) encoding a glycosyltransferase and its function in biosynthesis of exopolysaccharide in Streptomyces sp. 139
Qing-Li Sun et al.
Original research paper: Archives of Microbiology 188
doi:10.1007/s00203-007-0253-6Alkanethiol containing glycopolymers: A tool for the detection of lectin binding
M Huang et al.
Original research paper: Bioorganic & Medicinal Chemistry Letters 17
doi:10.1016/j.bmcl.2007.08.002Biological and therapeutic significance of MUC1 with sialoglycans in clear cell adenocarcinoma of the ovary
Yutaka Tamada et al.
Original research paper: Cancer Science 98
doi:10.1111/j.1349-7006.2007.00582.xSpectrum–Structure Relationship in Carbohydrate Vibrational Circular Dichroism and Its Application to Glycoconjugates
Tohru Taniguchi & Kenji Monde
Original research paper: Chemistry – An Asian Journal 2
doi:10.1002/asia.200700180Screening and diagnosis of congenital disorders of glycosylation
E Marklova & Z Albahri
Original research paper: Clinica Chimica Acta 385
doi:10.1016/j.cca.2007.07.002The three-dimensional structure of codakine and related marine C-type lectins
J Gourdine, A Markiv & J Smithravin
Original research paper: Fish & Shellfish Immunology 23
doi:10.1016/j.fsi.2007.03.009Biological Applications of a Chimeric Probe for the Assessment of Galectin-3 Ligands
F. H.M. De Melo et al.
Original research paper: Journal of Histochemistry and Cytochemistry 55
doi:10.1369/jhc.7A7174.2007Hepatocyte growth factor production is stimulated by gangliosides and TGF-β isoforms in human glioma cells
Sheng-hua Chu et al.
Original research paper: Journal of Neuro-Oncology 85
doi:10.1007/s11060-007-9387-2Two specific inhibitors of the phosphatidylinositol 3-kinase LY294002 and wortmannin up-regulate β1,4-galactosyltransferase I and thus sensitize SMMC-7721 human hepatocarcinoma cells to cycloheximide-induced apoptosis
Jialin Shen et al.
Original research paper: Molecular and Cellular Biochemistry 304
doi:10.1007/s11010-007-9519-1UDN glycoprotein inhibits activator protein-1 and matrix metalloproteinase-9 via blocking of oxygen radicals in HT-29 cells
Sei-Jung Lee & Kye-Taek Lim
Original research paper: Molecular and Cellular Biochemistry 304
doi:10.1007/s11010-007-9481-yEvaluation of docking programs for predicting binding of Golgi α-mannosidase II inhibitors: A comparison with crystallography
Pablo Englebienne et al.
Original research paper: Proteins: Structure, Function, and Bioinformatics 69
doi:10.1002/prot.21479Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation
E. Rajpert-de Meyts et al.
Original research paper: Virchows Archiv 451
doi:10.1007/s00428-007-0478-4Contrasting glycosylation profiles between Fab and Fc of a human IgG protein studied by electrospray ionization mass spectrometry
Y Mimura et al.
Original research paper: Journal of Immunological Methods 326
doi:10.1016/j.jim.2007.07.014The second glutamic acid in the C-terminal CRD affects the carbohydrate-binding properties of recombinant galectins of Haemonchus contortus
J Wang, R Yan, L Xu & X Li
Original research paper: Veterinary Parasitology 148
doi:10.1016/j.vetpar.2007.06.024Synthesis and binding properties of divalent and trivalent clusters of the Lewis a disaccharide moiety to Pseudomonas aeruginosa lectin PA-IIL
Karine Marotte et al.
Original research paper: Organic & Biomolecular Chemistry 5
doi:10.1039/b708227dOptimized synthesis of aminooxy-peptides as glycoprobe precursors for surface-based sugar–protein interaction studies
C Jimenez-Castells, B Delatorre, R Gutierrezgallego & D Andreu
Original research paper: Bioorganic & Medicinal Chemistry Letters 17
doi:10.1016/j.bmcl.2007.06.090