Research highlights
From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. Here, access the complete archive of Research Highlights, short accessible pieces that put into context must-read papers related to Functional Glycomics. Original pieces created by NPG as part of the NPG-CFG partnership are subject to copyright by the Nature Publishing Group, a division of Macmillan Publishers Limited; used with permission.
December 2007
Malaria infection: Heparan sulfate says open sesame
Proteolytic cleavage of the Plasmodium sporozoite cell surface circumsporozoite protein (CSP) is triggered by hepatocyte highly sulfated heparan sulfate proteoglycans (HSPGs), initiating a signaling pathway that involves calcium-dependent protein kinase (CDPK)-6 and leads to the switch from sporozoite migration to invasion.
Functional Glycomics Gateway (2007)
doi:10.1038/fg.2007.52Leukocyte recruitment: Selectin the way forward
Clathrin-coated pits and lipid raft membrane subdomains sequester E-selectin molecules and regulate the rolling of leukocytes toward sites of inflammation.
Functional Glycomics Gateway (2007)
doi:10.1038/fg.2007.53Cell proliferation: Rafting through the lattice
Cell surface glycan-galectin lattices interact with membrane microdomains and control the presence of molecules involved in signal transduction and endocytosis.
Functional Glycomics Gateway (2007)
doi:10.1038/fg.2007.54
