Research highlights
From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. Here, access the complete archive of Research Highlights, short accessible pieces that put into context must-read papers related to Functional Glycomics. Original pieces created by NPG as part of the NPG-CFG partnership are subject to copyright by the Nature Publishing Group, a division of Macmillan Publishers Limited; used with permission.
April 2008
Quality control: Lectins ERADicate misfolded proteins
OS-9 and XTP3-B are lectins residing in the lumen of the endoplasmatic reticulum (ER) that deliver misfolded proteins to the ubiquitin ligase complex SEL1/Hrd1.
Functional Glycomics Gateway (2008)
doi:10.1038/fg.2008.19Migration and anergy: The lattice strikes again
Cell surface galectin-glycan lattices (GGL), formed from galectin-3 (Gal-3) and
-galactoside ligands, regulate focal adhesion (FA) formation and disrupt the association of T-cell receptor (TCR) with CD8 in cytolytic lymphocytes (CTLs).Functional Glycomics Gateway (2008)
doi:10.1038/fg.2008.20Glycan-lectin binding: The polyvalent value of viruses
Glycan ligands can be built onto virus particles in a polyvalent fashion, which enables their binding to lectin receptors.
Functional Glycomics Gateway (2008)
doi:10.1038/fg.2008.21
