Functional Glycomics homepage

Featured articles

From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. Here, access the complete archive of Featured Articles, specially written editors' reviews on the most exciting findings in glycobiology. Original pieces created by NPG as part of the NPG-CFG partnership are subject to copyright by the Nature Publishing Group, a division of Macmillan Publishers Limited; used with permission.

  • July 2008

    • Alzheimer disease and protein turnover: A GlcNAc trick

      Protein turnover may be regulated by O-glycosylation with N-acetylglucosamine (GlcNAc), and an O-GlcNAcase-inhibitor complex and an O-GlcNAc transferase homolog reveal surprising new structural features.

      Original research paper: FASEB Journal, (23 April 2008)
      doi:10.1096/fj.07-102509

    • Neutrophil trafficking: CXCR2's icing on the cake

      Sialylation of the neutrophil CXCR2 receptor is required for its interaction with the chemokines CXCL8 and CXCL1, which induces neutrophil arrest and prepares neutrophil extravasation.

      Original research paper: Journal of Experimental Medicine 205, 1435-1446 (2008)
      doi:10.1084/jem.20070846

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