Research highlights
From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. Here, access the complete archive of Research Highlights, short accessible pieces that put into context must-read papers related to Functional Glycomics. Original pieces created by NPG as part of the NPG-CFG partnership are subject to copyright by the Nature Publishing Group, a division of Macmillan Publishers Limited; used with permission.
October 2008
Tumor cell invasion: Sugars let cells glide ahead
Low-molecular weight chondroitin sulfate molecules in the extracellular matrix promote metalloprotease-mediated cleavage of CD44's extracellular domain, thereby promoting the invasion of tumors into the surrounding tissue.
Functional Glycomics Gateway (2008)
doi:10.1038/fg.2008.45T cell maturation: The ups and downs of sialylation
Mice lacking the sialic acid transferase ST6Gal I show a significant reduction in T cells throughout T-cell maturation and an upregulation of proapoptotic genes.
Functional Glycomics Gateway (2008)
doi:10.1038/fg.2008.46
