Functional Glycomics homepage

Featured articles

From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. Here, access the complete archive of Featured Articles, specially written editors' reviews on the most exciting findings in glycobiology. Original pieces created by NPG as part of the NPG-CFG partnership are subject to copyright by the Nature Publishing Group, a division of Macmillan Publishers Limited; used with permission.

  • February 2009

    • Protein folding: Sweet signals for degradation

      The Man7GlcNAc2 sugar is produced by the Htm1p protein and functions as a flag for misfolded glycoproteins, which are recognised by the Yos9p lectin and targeted for degradation.

      Original research paper: J Cell Biol. 184, 159-172 (2008)
      doi:10.1083/jcb.200809198

    • Adaptive immunity: Rel-ative contributions of Raf and Syk

      Dectin-1 signals through Syk and Raf-1 to regulate activation of the noncanonical NF-kappaB pathway and TH cell differentiation in response to fungal infection.

      Original research paper: Nat. Immunology 10, 203-213 (2009)
      doi:10.1038/ni.1692.

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