Research highlights
From 2006-2011, the Consortium for Functional Glycomics (CFG) and the Nature Publishing Group (NPG) collaborated to provide the Functional Glycomics Update, a one-stop resource with monthly updates on the latest developments in glycobiology. Here, access the complete archive of Research Highlights, short accessible pieces that put into context must-read papers related to Functional Glycomics. Original pieces created by NPG as part of the NPG-CFG partnership are subject to copyright by the Nature Publishing Group, a division of Macmillan Publishers Limited; used with permission.
February 2009
N-glycan biosynthesis: Flipping for precursors
A specific enzyme named flippase translocates the precursor of all N-glycans from the cytoplasmic face to the lumen of the endoplasmic reticulum (ER).
Functional Glycomics Gateway (2009)
doi:10.1038/fg.2009.7Oligosaccharyltransferases: A sweet assembly line
Two isoforms of the oligosaccharyltransferase active site subunit cooperate to glycosylate polypeptides in the endoplasmic reticulum (ER) – one adds carbohydrate modifications to proteins as they are translated whereas the other is responsible for post-translational glycosylation of sites overlooked by the first enzyme.
Functional Glycomics Gateway (2009)
doi:10.1038/fg.2009.8
