Development/Differentiation
Notch-dependent control of myelopoiesis is regulated by fucosylation
L. Zhou et al.
Original research paper: Blood 112
doi:10.1182/blood-2007-11-115204Protein ubiquitination is modulated by O-GlcNAc glycosylation
C. Guinez et al.
Original research paper: The FASEB Journal 22
doi:10.1096/fj.07-102509MUC1 Oncoprotein Blocks Death Receptor-Mediated Apoptosis by Inhibiting Recruitment of Caspase-8
N. Agata et al.
Original research paper: Cancer Research 68
doi:10.1158/0008-5472.CAN-08-0464Regulation of Zebrafish Skeletogenesis by ext2/dackel and papst1/pinscher
Aurélie Clément et al.
Original research paper: PLoS Genetics 4
doi:10.1371/journal.pgen.1000136Spatiotemporal expression of chondroitin sulfate sulfotransferases in the postnatal developing mouse cerebellum
M. Ishii & N. Maeda
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn040Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors
S Kim et al.
Original research paper: Biochemical and Biophysical Research Communications 371
doi:10.1016/j.bbrc.2008.04.162Polysialic acid controls NCAM‐induced differentiation of neuronal precursors into calretinin‐positive olfactory bulb interneurons
Iris Röckle et al.
Original research paper: Developmental Neurobiology 68
doi:10.1002/dneu.20649Galectin-4 Controls Intestinal Inflammation by Selective Regulation of Peripheral and Mucosal T Cell Apoptosis and Cell Cycle
Daniela Paclik et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0002629The Adult Mouse Subependymal Zone Regenerates Efficiently in the Absence of Tenascin-C
I. Kazanis, A. Belhadi, A. Faissner & C. Ffrench-constant
Original research paper: Journal of Neuroscience 27
doi:10.1523/JNEUROSCI.3279-07.2007Runx2- and Histone Deacetylase 3-mediated Repression Is Relieved in Differentiating Human Osteoblast Cells to Allow High Bone Sialoprotein Expression
V. Lamour et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M705833200Development of the corticospinal tract in Semaphorin3A- and CD24-deficient mice
M Sibbe, M Taniguchi, M Schachner & U Bartsch
Original research paper: Neuroscience 150
doi:10.1016/j.neuroscience.2007.10.007DACS, novel matrix structure composed of chondroitin sulfate proteoglycan in the brain
N Hayashi et al.
Original research paper: Biochemical and Biophysical Research Communications 364
doi:10.1016/j.bbrc.2007.10.040Structure–Function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function
Ramesh A. Bhat, Barbara Stauffer, Barry S. Komm & Peter V.N. Bodine
Original research paper: Journal of Cellular Biochemistry 102
doi:10.1002/jcb.21372The O-fucose glycan in the ligand-binding domain of Notch1 regulates embryogenesis and T cell development
C. Ge & P. Stanley
Original research paper: Proceedings of the National Academy of Sciences 105
doi:10.1073/pnas.0702846105Galectin 15 (LGALS15) functions in trophectoderm migration and attachment
J. L. Farmer et al.
Original research paper: The FASEB Journal 22
doi:10.1096/fj.07-9308comImpact of the Polysialyltransferases ST8SiaII and ST8SiaIV on Polysialic Acid Synthesis during Postnatal Mouse Brain Development
I. Oltmann-norden et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M708463200Endothelial Cell Aging and Apoptosis in Prevention and Disease: E-Selectin Expression and Modulation As A Model
Douglas M. Noonan et al.
Original research paper: Current Pharmaceutical Design 14
doi:10.2174/138161208783413248Tetra- and hexavalent mannosides inhibit the pro-apoptotic, antiproliferative and cell surface clustering effects of concanavalin-A: Impact on MT1-MMP functions in marrow-derived mesenchymal stromal cells
S. Fortier et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwm133Accelerated Proliferation and Abnormal Differentiation of Epidermal Keratinocytes in Endo- -Galactosidase C Transgenic Mice
M. Misawa et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwm115Reduced 4 1 Integrin/VCAM-1 Interactions Lead to Impaired Pre-B Cell Repopulation in Alpha 1,6-Fucosyltransferase Deficient Mice
W. Li et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwm107Keyhole limpet hemocyanin induces the activation and maturation of human dendritic cells through the involvement of mannose receptor
P Presicce et al.
Original research paper: Molecular Immunology 45
doi:10.1016/j.molimm.2007.07.020Bridging structure with function: Structural, regulatory, and developmental role of laminins
J Tzu & M Marinkovich
Original research paper: The International Journal of Biochemistry & Cell Biology 40
doi:10.1016/j.biocel.2007.07.015Human galectins as sensors for apoptosis/necrosis-associated surface changes of granulocytes and lymphocytes
Alexandra Beer et al.
Original research paper: Cytometry Part A 73A
doi:10.1002/cyto.a.20510Polysialyltransferase expression is linked to neuronal migration in the developing and adult zebrafish
Sandra Rieger, Katrin Volkmann & Reinhard W. Köster
Original research paper: Developmental Dynamics 237
doi:10.1002/dvdy.21410Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells
S Varghese et al.
Original research paper: Matrix Biology 27
doi:10.1016/j.matbio.2007.07.002Temporal changes in the carbohydrates expressed on BG01 human embryonic stem cells during differentiation as embryoid bodies
Kimberly A. Wearne, Harry C. Winter & Irwin J. Goldstein
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9064-xDistinct contributions of β4GalNAcTA and β4GalNAcTB to Drosophila glycosphingolipid biosynthesis
Anita Stolz et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9069-5Increased levels of xylosyltransferase I correlate with the mineralization of the extracellular matrix during osteogenic differentiation of mesenchymal stem cells
B Muller
Original research paper: Matrix Biology 27
doi:10.1016/j.matbio.2007.09.005ciCD94-1, an ascidian multipurpose C-type lectin-like receptor expressed in Ciona intestinalis hemocytes and larval neural structures
Ivana Zucchetti et al.
Original research paper: Differentiation 76
doi:10.1111/j.1432-0436.2007.00214.xMolecular evolution and expression of zebrafish St8SiaIII, an alpha-2,8-sialyltransferase involved in myotome development
Joachim Bentrop et al.
Original research paper: Developmental Dynamics 237
doi:10.1002/dvdy.21451A sugar rush for developmental biology
C. L. R. Merry & C. M. Ward
Original research paper: Development 135
doi:10.1242/dev.018796The dyslexia-associated gene KIAA0319 encodes highly N- and O-glycosylated plasma membrane and secreted isoforms
A. Velayos-baeza, C. Toma, S. Paracchini & A. P. Monaco
Original research paper: Human Molecular Genetics 17
doi:10.1093/hmg/ddm358Heparan sulfate proteoglycans and their binding proteins in embryo implantation and placentation
C Kirnsafran, S Dsouza & D Carson
Original research paper: Seminars in Cell & Developmental Biology 19
doi:10.1016/j.semcdb.2007.07.013Knocking Down Glycosaminoglycan Synthesis
J. W. J. Wong
Original research paper: Journal of Neuroscience 28
doi:10.1523/JNEUROSCI.0079-08.2008CD43 promotes cell growth and helps to evade FAS-mediated apoptosis in non-hematopoietic cancer cells lacking the tumor suppressors p53 or ARF
L Kadaja-saarepuu et al.
Original research paper: Oncogene 27 1705-1715 (2007)
doi:10.1038/sj.onc.1210802Interaction of Syntenin-1 and the NG2 Proteoglycan in Migratory Oligodendrocyte Precursor Cells
N. Chatterjee et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M706074200Hyaluronan Facilitates Transforming Growth Factor- 1-mediated Fibroblast Proliferation
S. Meran et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M704819200Sialic acid metabolism is involved in the regulation of gene expression during neuronal differentiation of PC12 cells
Maria Kontou, Christian Bauer, Werner Reutter & Rüdiger Horstkorte
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-008-9104-1Targeting epileptogenesis-associated induction of neurogenesis by enzymatic depolysialylation of NCAM counteracts spatial learning dysfunction but fails to impact epilepsy development
Anton Pekcec et al.
Original research paper: Journal of Neurochemistry 105
doi:10.1111/j.1471-4159.2007.05172.xGalectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
M Seki et al.
Original research paper: Clinical Immunology 127
doi:10.1016/j.clim.2008.01.006Toll-Like Receptor Ligands Induce Human T Cell Activation and Death, a Model for HIV Pathogenesis
Nicholas Funderburg et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0001915Semaphorin signaling in morphogenesis: found in translation
A. D. Chisholm
Original research paper: Genes & Development 22
doi:10.1101/gad.1669308Trophoblast Differentiation Defect in Human Embryonic Stem Cells Lacking PIG-A and GPI-Anchored Cell-Surface Proteins
G Chen et al.
Original research paper: Cell Stem Cell 2
doi:10.1016/j.stem.2008.02.004Wollknauel is required for embryo patterning and encodes the Drosophila ALG5 UDP-glucose:dolichyl-phosphate glucosyltransferase
A. Haecker et al.
Original research paper: Development 135
doi:10.1242/dev.020891Structural Features of Galectin-9 and Galectin-1 That Determine Distinct T Cell Death Pathways
S. Bi, L. A. Earl, L. Jacobs & L. G. Baum
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M800523200GD3 nuclear localization after apoptosis induction in HUT-78 cells
I Tempera et al.
Original research paper: Biochemical and Biophysical Research Communications 368
doi:10.1016/j.bbrc.2007.12.196Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytes
Bettina Brandt et al.
Original research paper: Histochemistry and Cell Biology 129
doi:10.1007/s00418-008-0395-xLeishmania pifanoi Proteoglycolipid Complex P8 Induces Macrophage Cytokine Production through Toll-Like Receptor 4
S. M. Whitaker, M. Colmenares, K. G. Pestana & D. Mcmahon-pratt
Original research paper: Infection and Immunity 76
doi:10.1128/IAI.01528-07Glycodelin Protein and mRNA Is Downregulated in Human First Trimester Abortion and Partially Upregulated in Mole Pregnancy
B. Toth et al.
Original research paper: Journal of Histochemistry and Cytochemistry 56
doi:10.1369/jhc.2008.950600CLEC-38, A Transmembrane Protein with C-Type Lectin-Like Domains, Negatively Regulates UNC-40-Mediated Axon Outgrowth and Promotes Presynaptic Development in Caenorhabditis elegans
G. Kulkarni, H. Li & W. G. Wadsworth
Original research paper: Journal of Neuroscience 28
doi:10.1523/JNEUROSCI.5542-07.2008Differential changes in cell wall matrix polysaccharides and glycoside-hydrolyzing enzymes in developing wheat seedlings differing in drought tolerance
H Konno, Y Yamasaki, M Sugimoto & K Takeda
Original research paper: Journal of Plant Physiology 165
doi:10.1016/j.jplph.2007.07.007Semaphorin3a inhibits ureteric bud branching morphogenesis
A Tufro, J Teichman, C Woda & G Villegas
Original research paper: Mechanisms of Development 125
doi:10.1016/j.mod.2007.12.003Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis
L. Malaval et al.
Original research paper: Journal of Experimental Medicine 205
doi:10.1084/jem.20071294In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
S. T. Laughlin, J. M. Baskin, S. L. Amacher & C. R. Bertozzi
Original research paper: Science 320
doi:10.1126/science.1155106Combined Deficiency of Dystrophin and 1 Integrin in the Cardiac Myocyte Causes Myocardial Dysfunction, Fibrosis and Calcification
L. Elsherif et al.
Original research paper: Circulation Research 102
doi:10.1161/CIRCRESAHA.108.173153Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis: A LINK TO CERAMIDE SYNTHASE-3
M. Rabionet et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M800870200Opposing roles for glypicans in Hedgehog signalling
Glypican members of the heparan sulphate proteoglycan family regulate several developmental signalling pathways, such as those involving Hedgehog, Wnt, BMP and FGF. Two studies reveal opposite effects of glypicans on Hedgehog signalling and show how their core protein domains and GPI anchor contribute to their versatile biological functions.
Dong Yan & Xinhua Lin
Original research paper: Nature Cell Biology 10 761-763
doi:10.1038/ncb0708-761Glypican-3 Inhibits Hedgehog Signaling during Development by Competing with Patched for Hedgehog Binding
M Capurro et al.
Original research paper: Developmental Cell 14
doi:10.1016/j.devcel.2008.03.006Endogenous galectin-1 enforces class I-restricted TCR functional fate decisions in thymocytes
S. D. Liu et al.
Original research paper: Blood 112
doi:10.1182/blood-2007-09-114181Glycans in evolution and development. Workshop on Glycoscience and Development
Original research paper:
doi:10.1038/embor.2008.119Glypican-1 Regulates Anaphase Promoting Complex/Cyclosome Substrates and Cell Cycle Progression in Endothelial Cells
D. Qiao, X. Yang, K. Meyer & A. Friedl
Original research paper: Molecular Biology of the Cell 19
doi:10.1091/mbc.E07-10-1025Ganglioside Inhibition of Neurite Outgrowth Requires Nogo Receptor Function: IDENTIFICATION OF INTERACTION SITES AND DEVELOPMENT OF NOVEL ANTAGONISTS
G. Williams et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M802067200Two Heparanase Splicing Variants with Distinct Properties Are Necessary in Early Xenopus Development
G. E. Bertolesi, G. Michaiel & S. Mcfarlane
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M708525200A novel mutation in KNOPF uncovers the role of α-glucosidase I during post-embryonic development in Arabidopsis thaliana
C Furumizu & Y Komeda
Original research paper: FEBS Letters 582
doi:10.1016/j.febslet.2008.05.019A lectin receptor-like kinase is required for pollen development in Arabidopsis
Jinrong Wan et al.
Original research paper: Plant Molecular Biology 67
doi:10.1007/s11103-008-9332-6