Glycolipids
The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1
L. Veracini et al.
Original research paper: The Journal of Cell Biology 182
doi:10.1083/jcb.200705102Multifunctionality of Campylobacter jejuni sialyltransferase CstII: Characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities
J. Cheng et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn047Non-reducing end α-mannosylated glycolipids as potent activators for invariant Vα19 TCR-bearing natural killer T cells
M Shimamura
Original research paper: Carbohydrate Research 343
doi:10.1016/j.carres.2008.04.001β-Glycosphingolipids-mediated lipid raft alteration is associated with redistribution of NKT cells and increased intrahepatic CD8+ T lymphocyte trapping
G. Lalazar et al.
Original research paper: The Journal of Lipid Research 49
doi:10.1194/jlr.M800113-JLR200Essential roles of integrin-mediated signaling for the enhancement of malignant properties of melanomas based on the expression of GD3
Y Ohkawa et al.
Original research paper: Biochemical and Biophysical Research Communications 373
doi:10.1016/j.bbrc.2008.05.149Identification of gangliosides recognized by IgG anti-GalNAc-GD1a antibodies in bovine spinal motor neurons and motor nerves
H Yoshino et al.
Original research paper: Brain Research 1227
doi:10.1016/j.brainres.2008.06.020Human colorectal tumors and metastases express Gb3 and can be targeted by an intestinal pathogen-based delivery tool
T. Falguieres et al.
Original research paper: Molecular Cancer Therapeutics 7
doi:10.1158/1535-7163.MCT-08-0430A Fluorescent Glycolipid-Binding Peptide Probe Traces Cholesterol Dependent Microdomain-Derived Trafficking Pathways
Steffen Steinert et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0002933A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor
M. G. Paulick, M. B. Forstner, J. T. Groves & C. R. Bertozzi
Original research paper: Proceedings of the National Academy of Sciences 104
doi:10.1073/pnas.0710139104Mass Spectrometric Analysis of Intact Lipooligosaccharide: Direct Evidence for O-Acetylated Sialic Acids and Discovery of O-Linked Glycine Expressed by Campylobacter jejuni
M. Dzieciatkowska et al.
Original research paper: Biochemistry 46
doi:10.1021/bi701229kSynthesis of Tri-, Hexa-, and Nonasaccharide Subunits of the Atypical O-Antigen Polysaccharide of the Lipopolysaccharide from Danish Helicobacter pylori Strains
D.B. Fulse, H.B. Jeon & K.S. Kim
Original research paper: The Journal of Organic Chemistry 72
doi:10.1021/jo701531xIgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1
Hitoshi Suzuki et al.
Original research paper: Journal of Clinical Investigation
doi:10.1172/JCI33189Mechanism of botulinum neurotoxin B and G entry into hippocampal neurons
M. Dong et al.
Original research paper: The Journal of Cell Biology 179
doi:10.1083/jcb.200707184Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
N. G. Jones et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M706207200Sensitive detection of isoglobo and globo series tetraglycosylceramides in human thymus by ion trap mass spectrometry
Y. Li et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwm129Sensitive quantitation of isoglobotriaosylceramide in the presence of isobaric components using electrospray ionization-ion trap mass spectrometry
Y. Li et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwm127An exposed carboxyl group on sialic acid is essential for gangliosides to inhibit calcium uptake via the sarco/endoplasmic reticulum Ca -ATPase: relevance to gangliosidoses
Luba Ginzburg, Su-Chen Li, Yu-Teh Li & Anthony H. Futerman
Original research paper: Journal of Neurochemistry 0
doi:10.1111/j.1471-4159.2007.04983.xFine specificity of natural killer T cells against GD3 ganglioside and identification of GM3 as an inhibitory natural killer T-cell ligand
Jun-Eui Park et al.
Original research paper: Immunology 123
doi:10.1111/j.1365-2567.2007.02760.xCloning and functional characterization of two key enzymes of glycosphingolipid biosynthesis in the amphibianXenopus laevis
Melchor E. Luque et al.
Original research paper: Developmental Dynamics 237
doi:10.1002/dvdy.21406Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway
A. R. Todeschini, J. N. Dos santos, K. Handa & S.-i. Hakomori
Original research paper: Proceedings of the National Academy of Sciences 105
doi:10.1073/pnas.0709619104HPV-16 E5 oncoprotein upregulates lipid raft components caveolin-1 and ganglioside GM1 at the plasma membrane of cervical cells
F A Suprynowicz et al.
Original research paper: Oncogene 27 1071-1078 (2007)
doi:10.1038/sj.onc.1210725Inhibition of Multidrug Resistance by AdamantylGb3, a Globotriaosylceramide Analog
M. F. De rosa et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M705473200Distinct contributions of β4GalNAcTA and β4GalNAcTB to Drosophila glycosphingolipid biosynthesis
Anita Stolz et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9069-5Phage display-derived recombinant antibodies with TCR-like specificity against α-galactosylceramide and its analogues in complex with human CD1d molecules
Galit Denkberg et al.
Original research paper: European Journal of Immunology 38
doi:10.1002/eji.200737518GM1-induced activation of phosphatidylinositol 3-kinase: involvement of Trk receptors
Anne-Marie Duchemin, Qun Ren, Norton H. Neff & Maria Hadjiconstantinou
Original research paper: Journal of Neurochemistry 104
doi:10.1111/j.1471-4159.2007.05088.xCorrugoside, a new immunostimulatory α-galactoglycosphingolipid from the marine sponge Axinella corrugata☆
V Costantino et al.
Original research paper: Bioorganic & Medicinal Chemistry 16
doi:10.1016/j.bmc.2007.10.098Prominent increase in plasma ganglioside GM3 is associated with clinical manifestations of type I Gaucher disease
K Ghauharalivandervlugt et al.
Original research paper: Clinica Chimica Acta
doi:10.1016/j.cca.2007.12.001Cloning and functional characterization of two key enzymes of glycosphingolipid biosynthesis in the amphibianXenopus laevis
Melchor E. Luque et al.
Original research paper: Developmental Dynamics 237
doi:10.1002/dvdy.21460Overexpression of glucosylceramide synthase in associated with multidrug resistance of leukemia cells
P Xie et al.
Original research paper: Leukemia Research 32
doi:10.1016/j.leukres.2007.07.006Structural basis of GM1 ganglioside recognition by simian virus 40
U. Neu, K. Woellner, G. Gauglitz & T. Stehle
Original research paper: Proceedings of the National Academy of Sciences 105
doi:10.1073/pnas.0710301105GM1 and Tumor Necrosis Factor- , Overexpressed in Renal Cell Carcinoma, Synergize to Induce T-Cell Apoptosis
T. Das et al.
Original research paper: Cancer Research 68
doi:10.1158/0008-5472.CAN-07-6037Design and synthesis of versatile ganglioside probes for carbohydrate microarrays
Akihiro Imamura et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9102-8GM3, GM2 and GM1 mimics designed for biosensing: chemoenzymatic synthesis, target affinities and 900MHz NMR analysis
A Pukin et al.
Original research paper: Carbohydrate Research 343
doi:10.1016/j.carres.2008.01.007Matching IR-MALDI-o-TOF Mass Spectrometry with the TLC Overlay Binding Assay and Its Clinical Application for Tracing Tumor-Associated Glycosphingolipids in Hepatocellular and Pancreatic Cancer
U. Distler et al.
Original research paper: Analytical Chemistry 80
doi:10.1021/ac702071xAccelerated release of exosome-associated GM1 ganglioside (GM1) by endocytic pathway abnormality: another putative pathway for GM1-induced amyloid fibril formation
Kohei Yuyama, Naoki Yamamoto & Katsuhiko Yanagisawa
Original research paper: Journal of Neurochemistry 105
doi:10.1111/j.1471-4159.2007.05128.xCharacterization of Symmetric and Asymmetric Lipid Bilayers Composed of Varying Concentrations of Ganglioside GM1 and DPPC
R.Y. Patel & P.V. Balaji
Original research paper: Journal of Physical Chemistry B 112
doi:10.1021/jp075975lStructural studies on the neutral glycosphingolipids of Manduca sexta
D Abeytunga, L Oland, A Somogyi & R Polt
Original research paper: Bioorganic Chemistry
doi:10.1016/j.bioorg.2007.10.002Glycosylation induces shifts in the lateral distribution of cholesterol from ordered towards less ordered domains
K Halling, B Ramstedt & J Slotte
Original research paper: Biochimica et Biophysica Acta (BBA) - Biomembranes 1778
doi:10.1016/j.bbamem.2008.01.001The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium–host interaction
B. J. Appelmelk et al.
Original research paper: Cellular Microbiology 10
doi:10.1111/j.1462-5822.2007.01097.xGanglioside GM1 effects on the expression of nerve growth factor (NGF), Trk-A receptor, proinflammatory cytokines and on autoimmune diabetes onset in non-obese diabetic (NOD) mice
K Vieira et al.
Original research paper: Cytokine 42
doi:10.1016/j.cyto.2008.01.009Phospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi
M Salto et al.
Original research paper: Molecular and Biochemical Parasitology
doi:10.1016/j.molbiopara.2007.12.001Glucosylceramide accumulation is not confined to the lysosome in fibroblasts from patients with Gaucher disease
M Fuller et al.
Original research paper: Molecular Genetics and Metabolism 93
doi:10.1016/j.ymgme.2007.11.011Enhancement of HIV DNA vaccine immunogenicity by the NKT cell ligand, α-galactosylceramide
Y Huang et al.
Original research paper: Vaccine 26
doi:10.1016/j.vaccine.2008.02.002Tumor-Specific Hsp70 Plasma Membrane Localization Is Enabled by the Glycosphingolipid Gb3
Mathias Gehrmann et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0001925A minimal binding footprint on CD1d-glycolipid is a basis for selection of the unique human NKT TCR
K. S. Wun et al.
Original research paper: Journal of Experimental Medicine 205
doi:10.1084/jem.20072141Interaction of CD44 and hyaluronan is the dominant mechanism for neutrophil sequestration in inflamed liver sinusoids
B. Mcdonald et al.
Original research paper: Journal of Experimental Medicine 205
doi:10.1084/jem.20071765A cell-based reglucosylation assay demonstrates the role of GT1 in the quality control of a maturing glycoprotein
B. R. Pearse, L. Gabriel, N. Wang & D. N. Hebert
Original research paper: The Journal of Cell Biology 181
doi:10.1083/jcb.200712068Trophoblast Differentiation Defect in Human Embryonic Stem Cells Lacking PIG-A and GPI-Anchored Cell-Surface Proteins
G Chen et al.
Original research paper: Cell Stem Cell 2
doi:10.1016/j.stem.2008.02.004Glycosphingolipids in vascular endothelial cells: relationship of heterogeneity in Gb3Cer/CD77 receptor expression with differential Shiga toxin 1 cytotoxicity
Christian H. Schweppe et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9091-7Involvement of very long fatty acid-containing lactosylceramide in lactosylceramide-mediated superoxide generation and migration in neutrophils
Kazuhisa Iwabuchi et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9084-6First synthesis of two deoxy Lewisx pentaosyl glycosphingolipids
Yun Luo et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9077-5The AP-2 transcription factor is required for the ganglioside GM3-stimulated transcriptional regulation of a PTEN gene
H.-J. Choi et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn016Roles of complex gangliosides in the development of experimental autoimmune encephalomyelitis
K. Miyamoto et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn017Thematic Review Series: Sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a
P. Mukherjee et al.
Original research paper: The Journal of Lipid Research 49
doi:10.1194/jlr.R800006-JLR200Imaging MALDI Mass Spectrometry Using an Oscillating Capillary Nebulizer Matrix Coating System and Its Application to Analysis of Lipids in Brain from a Mouse Model of Tay-Sachs/Sandhoff Disease
Y. Chen et al.
Original research paper: Analytical Chemistry 80
doi:10.1021/ac702350gGD3 nuclear localization after apoptosis induction in HUT-78 cells
I Tempera et al.
Original research paper: Biochemical and Biophysical Research Communications 368
doi:10.1016/j.bbrc.2007.12.196Disruption of GM2/GD2 synthase gene resulted in overt expression of 9-O-acetyl GD3 irrespective of Tis21
Keiko Furukawa et al.
Original research paper: Journal of Neurochemistry 105
doi:10.1111/j.1471-4159.2008.05232.xMeasurement of the Binding of Cholera Toxin to GM1 Gangliosides on Solid Supported Lipid Bilayer Vesicles and Inhibition by Europium (III) Chloride
Thomas L. Williams & A. Toby A. Jenkins
Original research paper: Journal of the American Chemical Society 130
doi:10.1021/ja710543xGlycolipid-Dependent Sorting of Melanosomal from Lysosomal Membrane Proteins by Lumenal Determinants
Sophie Groux-degroote et al.
Original research paper: Traffic 9
doi:10.1111/j.1600-0854.2008.00740.xMale Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis: A LINK TO CERAMIDE SYNTHASE-3
M. Rabionet et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M800870200Mice deficient in Neu4 sialidase exhibit abnormal ganglioside catabolism and lysosomal storage
V. Seyrantepe et al.
Original research paper: Human Molecular Genetics 17
doi:10.1093/hmg/ddn043Effects of gangliosides on the differentiation of human mesenchymal stem cells into osteoblasts by modulating epidermal growth factor receptors
S Kim et al.
Original research paper: Biochemical and Biophysical Research Communications 371
doi:10.1016/j.bbrc.2008.04.162Identification and analysis of novel functional sites in human GD3-synthase
Y Gu & R Yu
Original research paper: Biochemical and Biophysical Research Communications 370
doi:10.1016/j.bbrc.2008.03.029Functional roles of N-glycans in cell signaling and cell adhesion in cancer
Yan-Yang Zhao et al.
Original research paper: Cancer Science 99
doi:10.1111/j.1349-7006.2008.00839.xSignal transduction pathways involved in interaction of galactosylceramide/sulfatide-containing liposomes with cultured oligodendrocytes and requirement for myelin basic protein and glycosphingolipids
Joan M. Boggs, Wen Gao & Yukie Hirahara
Original research paper: Journal of Neuroscience Research 86
doi:10.1002/jnr.21603A sialylation study of mouse brain gangliosides by MALDI a-TOF and o-TOF mass spectrometry
Mostafa Zarei et al.
Original research paper: Journal of Mass Spectrometry 43
doi:10.1002/jms.1367Thematic Review Series: Sphingolipids. Nuclear sphingolipids: metabolism and signaling
R. W. Ledeen & G. Wu
Original research paper: The Journal of Lipid Research 49
doi:10.1194/jlr.R800009-JLR200Thematic Review Series: Sphingolipids. Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease--a review
T. Ariga, M. P. Mcdonald & R. K. Yu
Original research paper: The Journal of Lipid Research 49
doi:10.1194/jlr.R800007-JLR200Identification of Further Elongation and Branching of Dimeric Type 1 Chain on Lactosylceramides from Colonic Adenocarcinoma by Tandem Mass Spectrometry Sequencing Analyses
Y.-Y. Fan et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M707274200Ganglioside Inhibition of Neurite Outgrowth Requires Nogo Receptor Function: IDENTIFICATION OF INTERACTION SITES AND DEVELOPMENT OF NOVEL ANTAGONISTS
G. Williams et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M802067200Impaired hypoglossal nerve regeneration in mutant mice lacking complex gangliosides: Down-regulation of neurotrophic factors and receptors as possible mechanisms
D. Kittaka et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn032Structural characterization of glycosylinositolphospholipids with a blood group type B sugar unit from the edible mushroom, Hypsizygus marmoreus
S. Itonori et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn0361,4GlcNAc-capped mucin-type O-glycan inhibits cholesterol -glucosyltransferase from Helicobacter pylori and suppresses H. pylori growth
H. Lee et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn037Adjuvant potential of archaeal synthetic glycolipid mimetics critically depends on the glyco head group structure
G D. Sprott, C. J Dicaire, J.-P. Cote & D. M Whitfield
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn038On-Line Nano-HPLC/ESI QTOF MS and Tandem MS for Separation, Detection, and Structural Elucidation of Human Erythrocytes Neutral Glycosphingolipid Mixture
Stephan Kirsch et al.
Original research paper: Analytical Chemistry 80
doi:10.1021/ac702175fAsymmetric Structural Features in Single Supported Lipid Bilayers Containing Cholesterol and GM1 Resolved with Synchrotron X-Ray Reflectivity
C. Reich et al.
Original research paper: Biophysical Journal 95
doi:10.1529/biophysj.107.113068α-Galactosylceramide-loaded, antigen-expressing B cells prime a wide spectrum of antitumor immunity
Yeon-Jeong Kim et al.
Original research paper: International Journal of Cancer 122
doi:10.1002/ijc.23444The Glycosylphosphatidylinositol Anchor: A Complex Membrane-Anchoring Structure for Proteins
Margot G. Paulick & Carolyn R. Bertozzi
Original research paper: Biochemistry 47
doi:10.1021/bi8006324Selection of a Carbohydrate-Binding Domain with a Helix-Loop-Helix Structure
Teruhiko Matsubara et al.
Original research paper: Biochemistry 47
doi:10.1021/bi8000837α-Lactosylceramide as a Novel "Sugar-Capped" CD1d Ligand for Natural Killer T Cells: Biased Cytokine Profile and Therapeutic Activities
Wenpeng Zhang et al.
Original research paper: ChemBioChem 9
doi:10.1002/cbic.200700625Ganglioside GD1a suppresses TNFα expression via Pkn1 at the transcriptional level in mouse osteosarcoma-derived FBJ cells
L Wang et al.
Original research paper: Biochemical and Biophysical Research Communications 371
doi:10.1016/j.bbrc.2008.04.053Coupling of fully automated chip-based electrospray ionization to high-capacity ion trap mass spectrometer for ganglioside analysis
R Almeida et al.
Original research paper: Analytical Biochemistry 378
doi:10.1016/j.ab.2008.03.039Glycosylphosphatidylinositol-induced cardiac myocyte death might contribute to the fatal outcome of Plasmodium falciparum malaria
Kathrin Wennicke et al.
Original research paper: Apoptosis 13
doi:10.1007/s10495-008-0217-6Humans Lack iGb3 Due to the Absence of Functional iGb3-Synthase: Implications for NKT Cell Development and Transplantation
Dale Christiansen et al.
Original research paper: PLoS Biology 6
doi:10.1371/journal.pbio.0060172Association of glycosylphosphatidylinositol-anchored protein with retroviral particles
C. Metzner et al.
Original research paper: The FASEB Journal 22
doi:10.1096/fj.08-108217Dimeric Galectin-8 Induces Phosphatidylserine Exposure in Leukocytes through Polylactosamine Recognition by the C-terminal Domain
S. R. Stowell et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M802495200Ganglioside depletion and EGF responses of human GM3 synthase-deficient fibroblasts
Y. Liu et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn039A highly efficient construction of GM1 epitope tetrasaccharide and its conjugation with KLH
Takeru Yoshikawa et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-008-9111-2Glycolipid binding epitopes involved in adherence of the periodontitis-associated bacterium Porphyromonas gingivalis
Ulrika Hallén, Jonas Ångström & Annika E. Björkner
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-008-9113-0The α-galactosyl derivatives of ganglioside GD1b are essential for the organization of lipid rafts in RBL-2H3 mast cells
A Silveiraesouza et al.
Original research paper: Experimental Cell Research 314
doi:10.1016/j.yexcr.2008.05.014CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences
William C. Florence, Rakesh K. Bhat & Sebastian Joyce
Original research paper: Expert Reviews in Molecular Medicine 10
doi:10.1017/S1462399408000732encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart and has functional and non-functional alleles in humans
Huan Cao et al.
Original research paper: European Journal of Immunology 38
doi:10.1002/eji.200738078Distinct Flippases Translocate Glycerophospholipids and Oligosaccharide Diphosphate Dolichols across the Endoplasmic Reticulum
Sumana Sanyal, Christian G. Frank & Anant K. Menon
Original research paper: Biochemistry 47
doi:10.1021/bi800723nMolecular Basis for Tetanus Toxin Coreceptor Interactions
Chen Chen, Michael R. Baldwin & Joseph T. Barbieri
Original research paper: Biochemistry 47
doi:10.1021/bi800640y