Glycoproteins/Proteoglycans
APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa
Bertrand Huard et al.
Original research paper: Journal of Clinical Investigation
doi:10.1172/JCI33760Protein ubiquitination is modulated by O-GlcNAc glycosylation
C. Guinez et al.
Original research paper: The FASEB Journal 22
doi:10.1096/fj.07-102509MUC1 Oncoprotein Blocks Death Receptor-Mediated Apoptosis by Inhibiting Recruitment of Caspase-8
N. Agata et al.
Original research paper: Cancer Research 68
doi:10.1158/0008-5472.CAN-08-0464Tumor stroma marker endosialin (Tem1) is a binding partner of metastasis-related protein Mac-2 BP/90K
R. Becker et al.
Original research paper: The FASEB Journal 22
doi:10.1096/fj.07-101386Association of glycosylphosphatidylinositol-anchored protein with retroviral particles
C. Metzner et al.
Original research paper: The FASEB Journal 22
doi:10.1096/fj.08-108217Regulation of Zebrafish Skeletogenesis by ext2/dackel and papst1/pinscher
Aurélie Clément et al.
Original research paper: PLoS Genetics 4
doi:10.1371/journal.pgen.1000136Hyaluronan in Cancer Biology
R Stern
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.04.001Association between cancer and "acid mucopolysaccharides": An old concept comes of age, finally
R Stern
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.014Hyaluronan: A constitutive regulator of chemoresistance and malignancy in cancer cells
B Toole & M Slomiany
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.009Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression
L Bourguignon
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.007Involvement of CD44, a molecule with a thousand faces, in cancer dissemination
D Naor, S Wallachdayan, M Zahalka & R Sionov
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.015Altered hyaluronan biosynthesis in cancer progression
N Itano & K Kimata
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.006Hyaluronidases in cancer biology
R Stern
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.017Hyalurondiase: Both a tumor promoter and suppressor
V Lokeshwar & M Selzer
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.008Hyaluronan in human tumors: Pathobiological and prognostic messages from cell-associated and stromal hyaluronan
R Tammi et al.
Original research paper: Seminars in Cancer Biology 18
doi:10.1016/j.semcancer.2008.03.005Sialic acids in human health and disease
A Varki
Original research paper: Trends in Molecular Medicine 14
doi:10.1016/j.molmed.2008.06.002Biological Functions of the Small Leucine-rich Proteoglycans: From Genetics to Signal Transduction
L. Schaefer & R. V. Iozzo
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.R800020200Syndecan-1 Is an in Vivo Suppressor of Gram-positive Toxic Shock
K. Hayashida, Y. Chen, A. H. Bartlett & P. W. Park
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M801614200N-Glycans and the N Terminus of Protein C Inhibitor Affect the Cofactor-enhanced Rates of Thrombin Inhibition
W. Sun et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M800608200Initiation of Mammalian O-Mannosylation in Vivo Is Independent of a Consensus Sequence and Controlled by Peptide Regions within and Upstream of the α-Dystroglycan Mucin Domain
I. Breloy et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M802834200Spatiotemporal expression of chondroitin sulfate sulfotransferases in the postnatal developing mouse cerebellum
M. Ishii & N. Maeda
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn040Mass spectrometric and linear discriminant analysis of N-glycans of human serum alpha-1-acid glycoprotein in cancer patients and healthy individuals
T Imre et al.
Original research paper: Journal of Proteomics 71
doi:10.1016/j.jprot.2008.04.005Imaging and tracking of single hyaluronan molecules diffusing in solution
Tim Kaminski et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-008-9112-1Chemical tools for functional studies of glycans
Sungjin Park, Myung-Ryul Lee & Injae Shin
Original research paper: Chemical Society Reviews 37
doi:10.1039/b713011mN-Glycosylation is required for Na+-dependent vitamin C transporter functionality
V Subramanian, J Marchant, J Reidling & H Said
Original research paper: Biochemical and Biophysical Research Communications 374
doi:10.1016/j.bbrc.2008.06.120A lectin recognizes differential arrangements of O-glycans on mucin repeats
K Kato et al.
Original research paper: Biochemical and Biophysical Research Communications 371
doi:10.1016/j.bbrc.2008.04.120N-Glycosylation of the Drosophila neural protein Chaoptin is essential for its stability, cell surface transport and adhesive activity
Y Hiraifujita, M Yamamotohino, O Kanie & S Goto
Original research paper: FEBS Letters 582
doi:10.1016/j.febslet.2008.06.028Rerouting of fibroblast growth factor 2 to the classical secretory pathway results in post-translational modifications that block binding to heparan sulfate proteoglycans
S Wegehingel, C Zehe & W Nickel
Original research paper: FEBS Letters 582
doi:10.1016/j.febslet.2008.05.042The Terminal Sialic Acid of Glycoconjugates on the Surface of Intestinal Epithelial Cells Activates Excystation of Cryptosporidium parvum
N. Choudhry, M. Bajaj-elliott & V. Mcdonald
Original research paper: Infection and Immunity 76
doi:10.1128/IAI.00362-08Thr but Asn of the N-glycosylation sites of PrP is indispensable for its misfolding
S Ikeda, A Kobayashi & T Kitamoto
Original research paper: Biochemical and Biophysical Research Communications 369
doi:10.1016/j.bbrc.2008.03.014Development of an enzyme-linked immunosorbent assay (ELISA)-like fluorescence assay to investigate the interactions of glycosaminoglycans to cells
R Boucas et al.
Original research paper: Analytica Chimica Acta 618
doi:10.1016/j.aca.2008.04.059Glycopeptide analysis by mass spectrometry
Dilusha S. Dalpathado & Heather Desaire
Original research paper: The Analyst 133
doi:10.1039/b713816dFunctional roles of N-glycans in cell signaling and cell adhesion in cancer
Yan-Yang Zhao et al.
Original research paper: Cancer Science 99
doi:10.1111/j.1349-7006.2008.00839.xNative human zona pellucida glycoproteins: purification and binding properties
P. C.N. Chiu et al.
Original research paper: Human Reproduction 23
doi:10.1093/humrep/den047Characteristics of Plasmodium falciparum-Infected-Erythrocyte Adhesion to Chondroitin Sulfate
J. G. Beeson, S. V. Madhunapantula, R. N. Achur & D. C. Gowda
Original research paper: Infection and Immunity 76
doi:10.1128/IAI.00178-08Site-specific analysis ofN-glycans on haptoglobin in sera of patients with pancreatic cancer: A novel approach for the development of tumor markers
Miyako Nakano et al.
Original research paper: International Journal of Cancer 122
doi:10.1002/ijc.23364FGFR4 and its novel splice form in myogenic cells: Interplay of glycosylation and tyrosine phosphorylation
Boguslaw A. Kwiatkowski et al.
Original research paper: Journal of Cellular Physiology 215
doi:10.1002/jcp.21365Env length and N-linked glycosylation following transmission of human immunodeficiency virus Type 1 subtype B viruses
Y Liu et al.
Original research paper: Virology 374
doi:10.1016/j.virol.2008.01.029Post-translational modifications in glycosylation status during epididymal passage and significance in fertility of a 33 kDa glycoprotein (MEF3) of rhesus monkey (Macaca mulatta)
A. Chandra et al.
Original research paper: Reproduction 135
doi:10.1530/REP-07-0525MUC1 Oncoprotein Regulates Bcr-Abl Stability and Pathogenesis in Chronic Myelogenous Leukemia Cells
T. Kawano et al.
Original research paper: Cancer Research 67
doi:10.1158/0008-5472.CAN-07-2756Site-Directed Conjugation of "Clicked" Glycopolymers To Form Glycoprotein Mimics: Binding to Mammalian Lectin and Induction of Immunological Function
J. Geng et al.
Original research paper: Journal of the American Chemical Society 129
doi:10.1021/ja072999xInhibiting Glycosaminoglycan Chain Polymerization Decreases the Inhibitory Activity of Astrocyte-Derived Chondroitin Sulfate Proteoglycans
T. L. Laabs et al.
Original research paper: Journal of Neuroscience 27
doi:10.1523/JNEUROSCI.2807-07.2007The Adult Mouse Subependymal Zone Regenerates Efficiently in the Absence of Tenascin-C
I. Kazanis, A. Belhadi, A. Faissner & C. Ffrench-constant
Original research paper: Journal of Neuroscience 27
doi:10.1523/JNEUROSCI.3279-07.2007Requirement of Glycosylphosphatidylinositol Anchor of Cripto-1 for trans Activity as a Nodal Co-receptor
K. Watanabe et al.
Original research paper: Journal of Biological Chemistry 282
doi:10.1074/jbc.M707351200Laminin-Induced Activation of Rac1 and JNKp46 Is Initiated by Src Family Kinases and Mimics the Effects of Skeletal Muscle Contraction
Y. Zhou, D. Jiang, D.B. Thomason & H.W. Jarrett
Original research paper: Biochemistry 46
doi:10.1021/bi701384kDACS, novel matrix structure composed of chondroitin sulfate proteoglycan in the brain
N Hayashi et al.
Original research paper: Biochemical and Biophysical Research Communications 364
doi:10.1016/j.bbrc.2007.10.040Co-expression of the toleragenic glycoprotein, CD200, with markers for cancer stem cells
B Kawasaki et al.
Original research paper: Biochemical and Biophysical Research Communications
doi:10.1016/j.bbrc.2007.10.067Association of chicken zona pellucida glycoprotein (ZP) B1 with ZPC induces formation of ZPB1–ZPC fibrous aggregates containing disulfide-bridged ZPB1 dimer☆
H Okumura, T Okajima, D Nadano & T Matsuda
Original research paper: Biochemical and Biophysical Research Communications
doi:10.1016/j.bbrc.2007.10.072Structure–Function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function
Ramesh A. Bhat, Barbara Stauffer, Barry S. Komm & Peter V.N. Bodine
Original research paper: Journal of Cellular Biochemistry 102
doi:10.1002/jcb.21372Ablation of the UPR-Mediator CHOP Restores Motor Function and Reduces Demyelination in Charcot-Marie-Tooth 1B Mice
M Pennuto et al.
Original research paper: Neuron 57
doi:10.1016/j.neuron.2007.12.021A Submicrogram-Scale Protocol for Biomolecule-Based PET Imaging by Rapid 6π-Azaelectrocyclization: Visualization of Sialic Acid Dependent Circulatory Residence of Glycoproteins
Katsunori Tanaka et al.
Original research paper: Angewandte Chemie International Edition 47
doi:10.1002/anie.200702989BlotGlycoABCTM, an Integrated Glycoblotting Technique for Rapid and Large Scale Clinical Glycomics
Y. Miura et al.
Original research paper: Molecular & Cellular Proteomics 7
doi:10.1074/mcp.M700377-MCP200Affinity of IgE and IgG against cross-reactive carbohydrate determinants on plant and insect glycoproteins
C Jin et al.
Original research paper: Journal of Allergy and Clinical Immunology 121
doi:10.1016/j.jaci.2007.07.047Effects of Macromolecular Crowding on Glycoprotein Processing Enzymes
K. Totani, Y. Ihara, I. Matsuo & Y. Ito
Original research paper: Journal of the American Chemical Society 130
doi:10.1021/ja077570kMass spectrometry-based proteomics of fungal wall glycoproteins
Q Yin, P Degroot, C Dekoster & F Klis
Original research paper: Trends in Microbiology 16
doi:10.1016/j.tim.2007.10.011Chemical Synthesis of a Glycoprotein Having an Intact Human Complex-Type Sialyloligosaccharide under the Boc and Fmoc Synthetic Strategies
N. Yamamoto et al.
Original research paper: Journal of the American Chemical Society 130
doi:10.1021/ja072543fHyaluronic Acid Synthase-1 Expression Regulates Bladder Cancer Growth, Invasion, and Angiogenesis through CD44
R. Golshani et al.
Original research paper: Cancer Research 68
doi:10.1158/0008-5472.CAN-07-2140SEA domain proteolysis determines the functional composition of dystroglycan
A. Akhavan et al.
Original research paper: The FASEB Journal 22
doi:10.1096/fj.07-8354comEndoplasmic Reticulum (ER) Mannosidase I Is Compartmentalized and Required for N-Glycan Trimming to Man5 6GlcNAc2 in Glycoprotein ER-associated Degradation
E. Avezov et al.
Original research paper: Molecular Biology of the Cell 19
doi:10.1091/mbc.E07-05-0505Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein
N. G. Jones et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M706207200Enzyme-dependent Variations in the Polysialylation of the Neural Cell Adhesion Molecule (NCAM) in Vivo
S. P. Galuska et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M707024200Glycoproteomic characterization of butyrylcholinesterase from human plasma
Daniel Kolarich et al.
Original research paper: PROTEOMICS 8
doi:10.1002/pmic.200700720Identification and Expression of Human Epiglycanin/MUC21: a Novel Transmembrane Mucin
Y. Itoh et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwm118Role of glycosaminoglycans for binding and infection of hepatitis B virus
Corinna M. Leistner, Stefanie Gruen-bernhard & Dieter Glebe
Original research paper: Cellular Microbiology 0
doi:10.1111/j.1462-5822.2007.01023.xAn Ectromelia Virus Protein That Interacts with Chemokines through Their Glycosaminoglycan Binding Domain
M. B. Ruiz-arguello et al.
Original research paper: Journal of Virology 82
doi:10.1128/JVI.02111-07Varicella-Zoster Virus Glycoprotein M Homolog Is Glycosylated, Is Expressed on the Viral Envelope, and Functions in Virus Cell-to-Cell Spread
Y. Yamagishi et al.
Original research paper: Journal of Virology 82
doi:10.1128/JVI.01722-07Adaptation of the Human Immunodeficiency Virus Type 1 Envelope Glycoproteins to New World Monkey Receptors
B. Pacheco et al.
Original research paper: Journal of Virology 82
doi:10.1128/JVI.01299-07Removal of a Single N-Linked Glycan in Human Immunodeficiency Virus Type 1 gp120 Results in an Enhanced Ability To Induce Neutralizing Antibody Responses
Y. Li et al.
Original research paper: Journal of Virology 82
doi:10.1128/JVI.01691-07Osteopontin as a new player in mast cell biology
Silvia Bulfone-paus & Ralf Paus
Original research paper: European Journal of Immunology 38
doi:10.1002/eji.200738131Chondroitin sulfate and heparan sulfate-containing proteoglycans are both partners and targets of basic fibroblast growth factor-mediated proliferation in human metastatic melanoma cell lines
D Nikitovic et al.
Original research paper: The International Journal of Biochemistry & Cell Biology 40
doi:10.1016/j.biocel.2007.06.019Bridging structure with function: Structural, regulatory, and developmental role of laminins
J Tzu & M Marinkovich
Original research paper: The International Journal of Biochemistry & Cell Biology 40
doi:10.1016/j.biocel.2007.07.015Inhibition of proteoglycan synthesis affects neuronal outgrowth and astrocytic migration in organotypic cultures of fetal ventral mesencephalon
Elisabet Berglöf, Stefan Plantman, Saga Johansson & Ingrid Strömberg
Original research paper: Journal of Neuroscience Research 86
doi:10.1002/jnr.21465Conformational Analysis of a Dermatan Sulfate-Derived Tetrasaccharide by NMR, Molecular Modeling, and Residual Dipolar Couplings
Alba Silipo et al.
Original research paper: ChemBioChem 9
doi:10.1002/cbic.200700400Chondroitin sulfate based niches for chondrogenic differentiation of mesenchymal stem cells
S Varghese et al.
Original research paper: Matrix Biology 27
doi:10.1016/j.matbio.2007.07.002Sialic acid moiety of apolipoprotein E3 at Thr194 affects its interaction with β-amyloid1–42 peptides
M Sugano
Original research paper: Clinica Chimica Acta 388
doi:10.1016/j.cca.2007.10.024Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer
Akeila Bellahcène et al.
Original research paper: Nature Reviews Cancer 8 212-226
doi:10.1038/nrc2345Engineering of mucin-type human glycoproteins in yeast cells
K. Amano et al.
Original research paper: Proceedings of the National Academy of Sciences 105
doi:10.1073/pnas.0710412105Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins
Shee-Mei Lok et al.
Original research paper: Nature Structural & Molecular Biology 15 312-317 (2008)
doi:10.1038/nsmb.1382Assessment of glycosaminoglycan concentration in vivo by chemical exchange-dependent saturation transfer (gagCEST)
W. Ling, R. R. Regatte, G. Navon & A. Jerschow
Original research paper: Proceedings of the National Academy of Sciences 105
doi:10.1073/pnas.0707666105Structural Analysis of Bikunin Glycosaminoglycan
L. Chi et al.
Original research paper: Journal of the American Chemical Society 130
doi:10.1021/ja0778500Interactions of Hepatocyte Growth Factor/Scatter Factor with Various Glycosaminoglycans Reveal an Important Interplay between the Presence of Iduronate and Sulfate Density
K. R. Catlow et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M706589200-2-Glycoprotein 1-dependent Macrophage Uptake of Apoptotic Cells: BINDING TO LIPOPROTEIN RECEPTOR-RELATED PROTEIN RECEPTOR FAMILY MEMBERS
S. N. Maiti, K. Balasubramanian, J. A. Ramoth & A. J. Schroit
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M704990200Vaccinia Virus A34 Glycoprotein Determines the Protein Composition of the Extracellular Virus Envelope
B. Perdiguero, M. M. Lorenzo & R. Blasco
Original research paper: Journal of Virology 82
doi:10.1128/JVI.01969-07Remarkable selective glycosylation of the immunoglobulin variable region in follicular lymphoma
K Mccann et al.
Original research paper: Molecular Immunology 45
doi:10.1016/j.molimm.2007.10.009Biochemical characterization of MLC1 protein in astrocytes and its association with the dystrophin–glycoprotein complex
E Ambrosini et al.
Original research paper: Molecular and Cellular Neuroscience 37
doi:10.1016/j.mcn.2007.11.003Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P-glycoprotein activity and PI3K/Akt pathway
Rosalía I. Cordo russo et al.
Original research paper: International Journal of Cancer 122
doi:10.1002/ijc.23122The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small intestine
Emily K. Malmberg et al.
Original research paper: Biochemical Journal 410
doi:10.1042/BJ20071068Investigating the biomarker potential of glycoproteins using comparative glycoprofiling — application to tissue inhibitor of metalloproteinases-1
M Thaysenandersen et al.
Original research paper: Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics 1784
doi:10.1016/j.bbapap.2007.12.007Monosialylated biantennary N-glycoforms containing GalNAc–GlcNAc antennae predominate when human EPO is expressed in goat milk
R Montesino et al.
Original research paper: Archives of Biochemistry and Biophysics 470
doi:10.1016/j.abb.2007.11.019The opportunistic fungal pathogen Scedosporium prolificans: Carbohydrate epitopes of its glycoproteins
E Barretobergter et al.
Original research paper: International Journal of Biological Macromolecules 42
doi:10.1016/j.ijbiomac.2007.09.015Receptor use by the Whitewater Arroyo virus glycoprotein
T Reignier
Original research paper: Virology 371
doi:10.1016/j.virol.2007.10.004HIV-1 p17 binds heparan sulfate proteoglycans to activated CD4+ T cells
C Poiesi, M Defrancesco, M Baronio & N Manca
Original research paper: Virus Research 132
doi:10.1016/j.virusres.2007.10.006The effect of glycosaminoglycans on rat gametes in vitro and the associated signal pathway
N. Borg & M. Holland
Original research paper: Reproduction 135
doi:10.1530/REP-07-0267The Murid Herpesvirus-4 gH/gL Binds to Glycosaminoglycans
Laurent Gillet, Susanna Colaco, Philip G. Stevenson & Peter Sommer
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0001669A sugar rush for developmental biology
C. L. R. Merry & C. M. Ward
Original research paper: Development 135
doi:10.1242/dev.018796The dyslexia-associated gene KIAA0319 encodes highly N- and O-glycosylated plasma membrane and secreted isoforms
A. Velayos-baeza, C. Toma, S. Paracchini & A. P. Monaco
Original research paper: Human Molecular Genetics 17
doi:10.1093/hmg/ddm358The Flavivirus Precursor Membrane-Envelope Protein Complex: Structure and Maturation
L. Li et al.
Original research paper: Science 319
doi:10.1126/science.1153263Structure and Function of the Polymeric Mucins in Airways Mucus
David J. Thornton, Karine Rousseau & Michael A. Mcguckin
Original research paper: Annual Review of Physiology 70
doi:10.1146/annurev.physiol.70.113006.100702Architecture of the large membrane-bound mucins
J Desseyn, D Tetaert & V Gouyer
Original research paper: Gene 410
doi:10.1016/j.gene.2007.12.014Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice
D. S. Woulfe et al.
Original research paper: Blood 111
doi:10.1182/blood-2007-07-104703N-linked glycosylation of VWF modulates its interaction with ADAMTS13
T. A. J. Mckinnon et al.
Original research paper: Blood 111
doi:10.1182/blood-2007-06-095042Disaccharide structure code for the easy representation of constituent oligosaccharides from glycosaminoglycans
Here we introduce a new shorthand nomenclature for designating the disaccharide subunit structure of all glycosaminoglycans as a way to compare compositions and describe linear sequences. Each disaccharide structural code (DSC) comprises four alphanumeric characters that reflect the actual substituents and isomeric characteristics of each component sugar. Larger structures can be represented easily by forming concatamers. The structural transparency of this new nomenclature eliminates the need for ambiguous acronyms or difficult numeric representations.
Roger Lawrence et al.
Original research paper: Nature Methods 5 291-292
doi:10.1038/nmeth0408-291Heparan sulfate proteoglycans and their binding proteins in embryo implantation and placentation
C Kirnsafran, S Dsouza & D Carson
Original research paper: Seminars in Cell & Developmental Biology 19
doi:10.1016/j.semcdb.2007.07.013Photoactivatable Crosslinking Sugars for Capturing Glycoprotein Interactions
Y. Tanaka & J.J. Kohler
Original research paper: Journal of the American Chemical Society 130
doi:10.1021/ja7109772Neuroactive Chondroitin Sulfate Glycomimetics
M. Rawat, C.I. Gama, J.B. Matson & L.C. Hsieh-wilson
Original research paper: Journal of the American Chemical Society 130
doi:10.1021/ja709993pMCF7 Side Population Cells with Characteristics of Cancer Stem/Progenitor Cells Express the Tumor Antigen MUC1
K. Engelmann, H. Shen & O. J. Finn
Original research paper: Cancer Research 68
doi:10.1158/0008-5472.CAN-07-2249Human Tumor Antigens Tn and Sialyl Tn Arise from Mutations in Cosmc
T. Ju et al.
Original research paper: Cancer Research 68
doi:10.1158/0008-5472.CAN-07-2345Structure, evolution, and biology of the MUC4 mucin
P. Chaturvedi, A. P. Singh & S. K. Batra
Original research paper: The FASEB Journal 22
doi:10.1096/fj.07-9673revHyaluronan Facilitates Transforming Growth Factor- 1-mediated Fibroblast Proliferation
S. Meran et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M704819200Laminin-1 is a novel carrier glycoprotein for the nonsulfated HNK-1 epitope in mouse kidney
Y. Kizuka et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn012Mouse Hyal3 encodes a 45- to 56-kDa glycoprotein whose overexpression increases hyaluronidase 1 activity in cultured cells
R. Hemming et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn006High-level expression of biologically active glycoprotein hormones in Pichia pastoris strains—selection of strain GS115, and not X-33, for the production of biologically active N-glycosylated 15N-labeled phCG
Véronique Blanchard et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9082-8Glycosylation of the two O-glycosylated domains of human MUC2 mucin in patients transposed with artificial urinary bladders constructed from proximal colonic tissue
Catherine Robbe-masselot et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9079-3Glycomic mapping of O- and N-linked glycans from major rat sublingual mucin
Shin-Yi Yu et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9071-yNatural and recombinant human glycodelin activate a proapoptotic gene cascade in monocyte cells
M. K. Tee, J.-L. Vigne, J. Yu & R. N. Taylor
Original research paper: Journal of Leukocyte Biology 83
doi:10.1189/jlb.0406291Characterization of Na,K-ATPase and H,K-ATPase Enzymes with Glycosylation-Deficient β-Subunit Variants by Voltage-Clamp Fluorometry in Xenopus Oocytes
Katharina L. Dürr et al.
Original research paper: Biochemistry 47
doi:10.1021/bi800092kIncreased plasma membrane localization of O-glycosylation-deficient mutant of synaptotagmin I in PC12 cells
Eiko Kanno & Mitsunori Fukuda
Original research paper: Journal of Neuroscience Research 86
doi:10.1002/jnr.21568Heparan Sulfate Proteoglycans in the Basement Membranes of the Human Placenta and Decidua
C Chen, S Liu, M Lee & Y Chen
Original research paper: Placenta 29
doi:10.1016/j.placenta.2008.01.002A Gamma-Herpesvirus Glycoprotein Complex Manipulates Actin to Promote Viral Spread
Michael B. Gill et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0001808Mice lacking the extracellular matrix protein MAGP1 display delayed thrombotic occlusion following vessel injury
C. C. Werneck et al.
Original research paper: Blood 111
doi:10.1182/blood-2007-07-101733Semaphorin signaling in morphogenesis: found in translation
A. D. Chisholm
Original research paper: Genes & Development 22
doi:10.1101/gad.1669308MUC1 Expression Is Regulated by DNA Methylation and Histone H3 Lysine 9 Modification in Cancer Cells
N. Yamada et al.
Original research paper: Cancer Research 68
doi:10.1158/0008-5472.CAN-07-6844Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations
H. G. Hocking et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M709587200Differentiating N-linked glycan structural isomers in metastatic and nonmetastatic tumor cells using sequential mass spectrometry
J. M. Prien et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn010Regioisomeric SCFA Attachment to Hexosamines Separates Metabolic Flux from Cytotoxicity and MUC1 Suppression
Udayanath Aich et al.
Original research paper: ACS Chemical Biology 3
doi:10.1021/cb7002708Modulation of protein stability by O-glycosylation in a designed Gc-MAF analog
J Spiriti, F Bogani, A Vandervaart & G Ghirlanda
Original research paper: Biophysical Chemistry 134
doi:10.1016/j.bpc.2008.02.005Differential expression of MUC1 and carbohydrate antigens in primary and secondary head and neck squamous cell carcinoma
María V. Croce, Martín E. Rabassa, Adrián Pereyra & Amada Segal-eiras
Original research paper: Head & Neck 30
doi:10.1002/hed.20756Aberrant IgA1 Glycosylation Is Inherited in Familial and Sporadic IgA Nephropathy
A. G. Gharavi et al.
Original research paper: Journal of the American Society of Nephrology 19
doi:10.1681/ASN.2007091052Glycodelin Protein and mRNA Is Downregulated in Human First Trimester Abortion and Partially Upregulated in Mole Pregnancy
B. Toth et al.
Original research paper: Journal of Histochemistry and Cytochemistry 56
doi:10.1369/jhc.2008.950600Hyposialylation of neprilysin possibly affects its expression and enzymatic activity in hereditary inclusion-body myopathy muscle
Aldobrando Broccolini et al.
Original research paper: Journal of Neurochemistry 105
doi:10.1111/j.1471-4159.2007.05208.xEfficient Synthesis of MUC4 Sialylglycopeptide through the New Sialylation Using 5-Acetamido-Neuraminamide Donors
Ryo Okamoto, Shingo Souma & Yasuhiro Kajihara
Original research paper: The Journal of Organic Chemistry 73
doi:10.1021/jo702609pSynthesis and antibody recognition of synthetic antigens from MUC1
Zoltán Bánóczi et al.
Original research paper: Journal of Peptide Science 14
doi:10.1002/psc.950Semaphorin3a inhibits ureteric bud branching morphogenesis
A Tufro, J Teichman, C Woda & G Villegas
Original research paper: Mechanisms of Development 125
doi:10.1016/j.mod.2007.12.003LysM, a widely distributed protein motif for binding to (peptido)glycans
Girbe Buist, Anton Steen, Jan Kok & Oscar P. Kuipers
Original research paper: Molecular Microbiology 68
doi:10.1111/j.1365-2958.2008.06211.xGlycan microarray analysis of Candida glabrata adhesin ligand specificity
Margaret L. Zupancic et al.
Original research paper: Molecular Microbiology 68
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Sanjeev Mahanta et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0002054Sialoadhesin Expressed on IFN-Induced Monocytes Binds HIV-1 and Enhances Infectivity
Hans Rempel et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0001967Expression and characterization of human glycosylated interleukin-1 receptor antagonist in Pichia pastoris
B Hamilton, Y Brede & T Tolbert
Original research paper: Protein Expression and Purification 59
doi:10.1016/j.pep.2008.01.003Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis
L. Malaval et al.
Original research paper: Journal of Experimental Medicine 205
doi:10.1084/jem.20071294Selective release of molecules from Weibel-Palade bodies during a lingering kiss
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Original research paper: Blood 111
doi:10.1182/blood-2007-09-113746Structural basis for NKG2A/CD94 recognition of HLA-E
B. K. Kaiser, J. C. Pizarro, J. Kerns & R. K. Strong
Original research paper: Proceedings of the National Academy of Sciences 105
doi:10.1073/pnas.0802736105Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection
B. F. Keele et al.
Original research paper: Proceedings of the National Academy of Sciences 105
doi:10.1073/pnas.0802203105Hyaluronan fragments generated by sperm-secreted hyaluronidase stimulate cytokine/chemokine production via the TLR2 and TLR4 pathway in cumulus cells of ovulated COCs, which may enhance fertilization
M. Shimada et al.
Original research paper: Development 135
doi:10.1242/dev.020461Combined Deficiency of Dystrophin and 1 Integrin in the Cardiac Myocyte Causes Myocardial Dysfunction, Fibrosis and Calcification
L. Elsherif et al.
Original research paper: Circulation Research 102
doi:10.1161/CIRCRESAHA.108.173153The Hyaluronan Receptor for Endocytosis Mediates Hyaluronan-dependent Signal Transduction via Extracellular Signal-regulated Kinases
S. V. Kyosseva, E. N. Harris & P. H. Weigel
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M709921200Porcine Dentin Sialophosphoprotein: LENGTH POLYMORPHISMS, GLYCOSYLATION, PHOSPHORYLATION, AND STABILITY
Y. Yamakoshi et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M800633200Cryptococcal Xylosyltransferase 1 (Cxt1p) from Cryptococcus neoformans Plays a Direct Role in the Synthesis of Capsule Polysaccharides
J. S. Klutts & T. L. Doering
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M708927200Hyaluronan Constitutively Regulates Activation of COX-2-mediated Cell Survival Activity in Intestinal Epithelial and Colon Carcinoma Cells
S. Misra et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M703811200Clusterin Activates Survival through the Phosphatidylinositol 3-Kinase/Akt Pathway
H. Ammar & J. L. Closset
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M800403200A simplified and sensitive fluorescent method for disaccharide analysis of both heparan sulfate and chondroitin/dermatan sulfates from biological samples
J. A Deakin & M. Lyon
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn028Analyzing the functions of large glycoconjugates through the dissipative properties of their absorbed layers using the gel-forming mucin MUC5B as an example
M. Kesimer & J. K Sheehan
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn024The O-linked glycosylation of secretory/shed MUC1 from an advanced breast cancer patient's serum
S. J Storr et al.
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn022Egg box conformation of oligogalacturonides: The time-dependent stabilization of the elicitor-active conformation increases its biological activity
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Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn027The structural plasticity of heparan sulfate NA-domains and hence their role in mediating multivalent interactions is confirmed by high-accuracy 15N-NMR relaxation studies
Mehdi Mobli, Mathias Nilsson & Andrew Almond
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9081-9Is human placenta proteoglycan remodeling involved in pre-eclampsia?
Mohamad Warda et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9090-8Sequence determination of a non-sulfated glycosaminoglycan-like polysaccharide from melanin-free ink of the squid Ommastrephes bartrami by negative-ion electrospray tandem mass spectrometry and NMR spectroscopy
Shiguo Chen et al.
Original research paper: Glycoconjugate Journal 25
doi:10.1007/s10719-007-9096-2Heparan sulfate proteoglycans and triglyceride-rich lipoprotein metabolism
Joseph R Bishop, Kristin I Stanford & Jeffrey D Esko
Original research paper: Current Opinion in Lipidology 19
doi:10.1097/MOL.0b013e3282feec2dRetina development in zebrafish requires the heparan sulfate proteoglycan agrin
I-Hsuan Liu, Chengjin Zhang, Min Jung Kim & Gregory J. Cole
Original research paper: Developmental Neurobiology 68
doi:10.1002/dneu.20625Analysis of Glycopeptides Using Lectin Affinity Chromatography with MALDI-TOF Mass Spectrometry
Kazutosi Kubota et al.
Original research paper: Analytical Chemistry 80
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J Creaney et al.
Original research paper: British Journal of Cancer 98 1562-1569 (2008)
doi:10.1038/sj.bjc.6604340N-glycosylation analysis of the human Tweety family of putative chloride ion channels supports a penta-spanning membrane arrangement: impact of N-glycosylation on cellular processing of Tweety homologue 2 (TTYH2)
Yaowu He et al.
Original research paper: Biochemical Journal 412
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Alka Jain, Larry W. Fisher & Neal S. Fedarko
Original research paper: Biochemistry 47
doi:10.1021/bi800133nHypoxia induces expression of a GPI-anchorless splice variant of the prion protein
Yutaka Kikuchi et al.
Original research paper: FEBS Journal 275
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E Selcukunal, R Zhao, A Qiu & I Goldman
Original research paper: Biochimica et Biophysica Acta (BBA) - Biomembranes 1778
doi:10.1016/j.bbamem.2008.03.009Nectin-like molecule 1 is a glycoprotein with a single N-glycosylation site at N290KS which influences its adhesion activity
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Original research paper: Biochimica et Biophysica Acta (BBA) - Biomembranes 1778
doi:10.1016/j.bbamem.2008.03.013Functional role of N-glycosylation from ADAM10 in processing, localization and activity of the enzyme
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Original research paper: Biochimica et Biophysica Acta (BBA) - General Subjects 1780
doi:10.1016/j.bbagen.2008.03.004Role of the Membrane-Spanning Domain of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein in Cell-Cell Fusion and Virus Infection
L. Shang, L. Yue & E. Hunter
Original research paper: Journal of Virology 82
doi:10.1128/JVI.02666-07Glycosylation of Asn-76 in mouse GPIHBP1 is critical for its appearance on the cell surface and the binding of chylomicrons and lipoprotein lipase
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Original research paper: The Journal of Lipid Research 49
doi:10.1194/jlr.M700593-JLR200Opposing roles for glypicans in Hedgehog signalling
Glypican members of the heparan sulphate proteoglycan family regulate several developmental signalling pathways, such as those involving Hedgehog, Wnt, BMP and FGF. Two studies reveal opposite effects of glypicans on Hedgehog signalling and show how their core protein domains and GPI anchor contribute to their versatile biological functions.
Dong Yan & Xinhua Lin
Original research paper: Nature Cell Biology 10 761-763
doi:10.1038/ncb0708-761Glypican-3 Inhibits Hedgehog Signaling during Development by Competing with Patched for Hedgehog Binding
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Original research paper: Developmental Cell 14
doi:10.1016/j.devcel.2008.03.006Glycans in evolution and development. Workshop on Glycoscience and Development
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Original research paper: Journal of the American Chemical Society 130
doi:10.1021/ja801468bO-Glucosylation and O-Fucosylation Occur Together in Close Proximity on the First Epidermal Growth Factor Repeat of AMACO (VWA2 Protein)
J. M. Gebauer et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M704820200The Human Hyaluronan Receptor for Endocytosis (HARE/Stabilin-2) Is a Systemic Clearance Receptor for Heparin
E. N. Harris, J. A. Weigel & P. H. Weigel
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M710360200Redundant Mechanism of Platelet Adhesion to Laminin and Collagen under Flow: INVOLVEMENT OF VON WILLEBRAND FACTOR AND GLYCOPROTEIN Ib-IX-V
O. Inoue, K. Suzuki-inoue & Y. Ozaki
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.C700241200N-Linked Glycosylation Selectively Regulates the Generic Folding of HLA-Cw1
A. Martayan et al.
Original research paper: Journal of Biological Chemistry 283
doi:10.1074/jbc.M709175200Analysis of the N-glycans of recombinant human Factor IX purified from transgenic pig milk
G.-C. Gil, W. H Velander & K. E Van cott
Original research paper: Glycobiology 18
doi:10.1093/glycob/cwn035Quantitative Derivatization of Sialic Acids for the Detection of Sialoglycans by MALDI MS
Masaaki Toyoda et al.
Original research paper: Analytical Chemistry 80
doi:10.1021/ac800457aUsing Detonation Nanodiamond for the Specific Capture of Glycoproteins
Weng Siang Yeap, Yee Ying Tan & Kian Ping Loh
Original research paper: Analytical Chemistry 80
doi:10.1021/ac800009vExpression of CD175 (Tn), CD175s (sialosyl-Tn) and CD176 (Thomsen-Friedenreich antigen) on malignant human hematopoietic cells
Yi Cao et al.
Original research paper: International Journal of Cancer 123
doi:10.1002/ijc.23493Effect of glycosylation on the extracellular domain of the Ag43 bacterial autotransporter: enhanced stability and reduced cellular aggregation
Stine K. Knudsen et al.
Original research paper: Biochemical Journal 412
doi:10.1042/BJ20071497Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b
Ivan Kadurin et al.
Original research paper: Biochemical Journal 412
doi:10.1042/BJ20071614Identification of the N-Linked Glycosylation Sites of the Human Relaxin Receptor and Effect of Glycosylation on Receptor Function
Y. Yan et al.
Original research paper: Biochemistry 47
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I Gladysheva, S King & A Houng
Original research paper: Biochemical and Biophysical Research Communications 373
doi:10.1016/j.bbrc.2008.05.181Heparanase Facilitates Cell Adhesion and Spreading by Clustering of Cell Surface Heparan Sulfate Proteoglycans
Flonia Levy-adam et al.
Original research paper: PLoS ONE 3
doi:10.1371/journal.pone.0002319Glypican-3 is overexpressed in lung squamous cell carcinoma, but not in adenocarcinoma
Sarit Aviel-ronen et al.
Original research paper: Modern Pathology 21 817-825 (2008)
doi:10.1038/modpathol.2008.37The Function of the Human Interferon- 1a Glycan Determined in Vivo
L. Dissing-olesen et al.
Original research paper: Journal of Pharmacology and Experimental Therapeutics 326
doi:10.1124/jpet.108.138263Sequential One-Pot Glycosidations Catalytically Promoted: Unprecedented Strategy in Oligosaccharide Synthesis for the Straightforward Assemblage of the Antitumor PI-88 Pentasaccharide
Silvia Valerio, Antonello Pastore, Matteo Adinolfi & Alfonso Iadonisi
Original research paper: The Journal of Organic Chemistry 73
doi:10.1021/jo8003953Defining the N-linked glycosylation site of hantaan virus envelope glycoproteins essential for cell fusion
Feng Zheng et al.
Original research paper: The Journal of Microbiology 46
doi:10.1007/s12275-006-0149-1Can glycans unveil the origin of glycoprotein hormones?—human chorionic gonadotrophin as an example—
R. Ramírez‐llanelis et al.
Original research paper: Journal of Mass Spectrometry 43
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