Immunology

• A novel strategy for evasion of NK cell immunity by tumours expressing core2 O-glycans

  Shigeru Tsuboi et al.
  Original research paper: The EMBO Journal (2011)
  doi:10.1038/emboj.2011.215

  Abstract

• Protection from Endogenous Perforin: Glycans and the C Terminus Regulate Exocytic Trafficking in Cytotoxic Lymphocytes

  Amelia J. Brennan et al.
  Original research paper: Immunity 34
  doi:10.1016/j.immuni.2011.04.007

  Abstract

• Limiting CDR-H3 Diversity Abrogates the Antibody Response to the Bacterial Polysaccharide   1->3 Dextran

  T. I. Mahmoud, H. W. Schroeder & J. F. Kearney
  Original research paper: The Journal of Immunology
  doi:10.4049/jimmunol.1100957

  Abstract

• Recognition of the Major Cat Allergen Fel d 1 through the Cysteine-rich Domain of the Mannose Receptor Determines Its Allergenicity

  M. Emara et al.
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M111.220657

  Abstract

• Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin

  M.-W. Chen et al.
  Original research paper: Proceedings of the National Academy of Sciences 108
  doi:10.1073/pnas.1019744108

  Abstract

• Switching on cytotoxicity by a single mutation at the heavy chain variable region of an anti-ganglioside antibody

  Yuniel Fernández-marrero et al.
  Original research paper: Molecular Immunology 48
  doi:10.1016/j.molimm.2011.01.008

  Abstract

• Anti-NeuGcGM3 Antibodies, Actively Elicited by Idiotypic Vaccination in Nonsmall Cell Lung Cancer Patients, Induce Tumor Cell Death by an Oncosis-Like Mechanism

  A. M. Hernandez et al.
  Original research paper: The Journal of Immunology 186
  doi:10.4049/jimmunol.1000609

  Abstract

• Oligosaccharide conjugates of Bordetella pertussis and bronchiseptica induce bactericidal antibodies, an addition to pertussis vaccine

  J. Kubler-kielb et al.
  Original research paper: Proceedings of the National Academy of Sciences 108
  doi:10.1073/pnas.1100782108

  Abstract

• Peptidoglycan recognition proteins kill bacteria by activating protein-sensing two-component systems

  Des Raj Kashyap et al.
  Original research paper: Nature Medicine 17 676-683 (2011)
  doi:10.1038/nm.2357

  Abstract

• Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

  Sandrine Aspeslagh et al.
  Original research paper: The EMBO Journal 30 2294-2305 (2011)
  doi:10.1038/emboj.2011.145

  Abstract

• Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

  K. A. Swanson et al.
  Original research paper: Proceedings of the National Academy of Sciences 108
  doi:10.1073/pnas.1106536108

  Abstract

• Binding of  -thrombin to surface-anchored platelet glycoprotein Ib  sulfotyrosines through a two-site mechanism involving exosite I

  A. Zarpellon et al.
  Original research paper: Proceedings of the National Academy of Sciences 108
  doi:10.1073/pnas.1017042108

  Abstract

• Advanced Glycation End Product Recognition by the Receptor for AGEs

  Jing Xue et al.
  Original research paper: Structure 19
  doi:10.1016/j.str.2011.02.013

  Abstract

• Tracing Protein Evolution through Ancestral Structures of Fish Galectin

  Ayumu Konno et al.
  Original research paper: Structure 19
  doi:10.1016/j.str.2011.02.014

  Abstract

• Sarm1, a negative regulator of innate immunity, interacts with syndecan-2 and regulates neuronal morphology

  C.-Y. Chen et al.
  Original research paper: The Journal of Cell Biology 193
  doi:10.1083/jcb.201008050

  Abstract

• Production of Multiple Brain-Like Ganglioside Species Is Dispensable for Fas-Induced Apoptosis of Lymphoid Cells

  Iuliana Popa et al.
  Original research paper: PLoS ONE 6
  doi:10.1371/journal.pone.0019974

  Abstract

• Modulation of the CD95-Induced Apoptosis: The Role of CD95 N-Glycosylation

  Olga M. Shatnyeva et al.
  Original research paper: PLoS ONE 6
  doi:10.1371/journal.pone.0019927

  Abstract

• Glycosylation regulates the specific induction of rice immune responses by Acidovorax avenae flagellin

  H. Hirai et al.
  Original research paper: Journal of Biological Chemistry
  doi:10.1074/jbc.M111.254029

  Abstract

• Extensive mannose phosphorylation on leukemia inhibitory factor (LIF) controls its extracellular levels by multiple mechanisms

  J. Barnes et al.
  Original research paper: Journal of Biological Chemistry
  doi:10.1074/jbc.M111.221432

  Abstract

• Glycosylation affects ligand binding and function of the activating Natural Killer cell receptor 2B4 (CD244)

  S. Margraf-schoenfeld, C. Boehm & C. Watzl
  Original research paper: Journal of Biological Chemistry
  doi:10.1074/jbc.M111.225334

  Abstract

•  2-Glycoprotein I and Protection from Anti-SSA/Ro60-Associated Cardiac Manifestations of Neonatal Lupus

  J. H. Reed et al.
  Original research paper: The Journal of Immunology 187
  doi:10.4049/jimmunol.1100122

  Abstract

• Lack of Galectin-3 Disturbs Mesenteric Lymph Node Homeostasis and B Cell Niches in the Course of Schistosoma mansoni Infection

  Felipe L. Oliveira et al.
  Original research paper: PLoS ONE 6
  doi:10.1371/journal.pone.0019216

  Abstract

• Galectin-1-expressing stromal cells constitute a specific niche for pre-BII cell development in mouse bone marrow

  F. Mourcin et al.
  Original research paper: Blood 117
  doi:10.1182/blood-2010-12-323113

  Abstract

• MHCII glycosylation modulates Bacteroides fragilis carbohydrate antigen presentation

  S. O. Ryan, J. A. Bonomo, F. Zhao & B. A. Cobb
  Original research paper: Journal of Experimental Medicine 208
  doi:10.1084/jem.20100508

  Abstract

• Advanced glycation end products of human  2 glycoprotein I modulate the maturation and function of DCs

  B. Buttari et al.
  Original research paper: Blood 117
  doi:10.1182/blood-2010-12-325514

  Abstract

• Role of Glomerular Proteoglycans in IgA Nephropathy

  Kerstin Ebefors et al.
  Original research paper: PLoS ONE 6
  doi:10.1371/journal.pone.0018575

  Abstract

• HIV-1 p17 Matrix Protein Interacts with Heparan Sulfate Side Chain of CD44v3, Syndecan-2, and Syndecan-4 Proteoglycans Expressed on Human Activated CD4+ T Cells Affecting Tumor Necrosis Factor   and Interleukin 2 Production

  M. A. De francesco, M. Baronio & C. Poiesi
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.191270

  Abstract

• Reduced Immunogenicity of Arabidopsis hgl1 Mutant N-Glycans Caused by Altered Accessibility of Xylose and core Fucose Epitopes

  H. Kaulfurst-soboll et al.
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.196097

  Abstract

• Differential Use of Chondroitin Sulfate to Regulate Hyaluronan Binding by Receptor CD44 in Inflammatory and Interleukin 4-activated Macrophages

  B. Ruffell et al.
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.200790

  Abstract

• A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules

  W. Zhang et al.
  Original research paper: Proceedings of the National Academy of Sciences 108
  doi:10.1073/pnas.1102527108

  Abstract

• Essential glycan-dependent interactions optimize MHC class I peptide loading

  P. A. Wearsch, D. R. Peaper & P. Cresswell
  Original research paper: Proceedings of the National Academy of Sciences 108
  doi:10.1073/pnas.1102524108

  Abstract

•  -Galactosylceramide-Induced Airway Eosinophilia Is Mediated through the Activation of NKT Cells

  Y.-H. Chuang et al.
  Original research paper: The Journal of Immunology 186
  doi:10.4049/jimmunol.1003659

  Abstract

• Design of Glycopeptides Used to Investigate Class II MHC Binding and T-Cell Responses Associated with Autoimmune Arthritis

  Ida E. Andersson et al.
  Original research paper: PLoS ONE 6
  doi:10.1371/journal.pone.0017881

  Abstract

• G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction

  B. Hayee et al.
  Original research paper: Glycobiology 21
  doi:10.1093/glycob/cwr023

  Abstract

• The Novel Neutrophil Differentiation Marker Phosphatidylglucoside Mediates Neutrophil Apoptosis

  K. Kina et al.
  Original research paper: The Journal of Immunology 186
  doi:10.4049/jimmunol.1002100

  Abstract

• Fungal Recognition Enhances Mannose Receptor Shedding through Dectin-1 Engagement

  U. Gazi et al.
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.185025

  Abstract

• Syndecan-1 Promotes Staphylococcus aureus Corneal Infection by Counteracting Neutrophil-mediated Host Defense

  A. Hayashida, S. Amano & P. W. Park
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.185165

  Abstract

• A Role for Serglycin Proteoglycan in Mast Cell Apoptosis Induced by a Secretory Granule-mediated Pathway

  F. R. Melo et al.
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.176461

  Abstract

• Dysregulation of TIM-3-Galectin-9 Pathway in the Cystic Fibrosis Airways

  I. Vega-carrascal et al.
  Original research paper: The Journal of Immunology 186
  doi:10.4049/jimmunol.1003187

  Abstract

• Suppressive Effect of Bacterial Polysaccharides on BAFF System Is Responsible for Their Poor Immunogenicity

  S. Kanswal et al.
  Original research paper: The Journal of Immunology 186
  doi:10.4049/jimmunol.1002976

  Abstract

• Distinct Functions for the Glycans of Tapasin and Heavy Chains in the Assembly of MHC Class I Molecules

  S. M. Rizvi, N. Del cid, L. Lybarger & M. Raghavan
  Original research paper: The Journal of Immunology 186
  doi:10.4049/jimmunol.1002959

  Abstract

• Mouse and human iNKT cell agonist β-mannosylceramide reveals a distinct mechanism of tumor immunity

  Jessica J. O’konek et al.
  Original research paper: Journal of Clinical Investigation 121
  doi:10.1172/JCI42314

  Abstract

• Meningococcal Group W-135 and Y Capsular Polysaccharides Paradoxically Enhance Activation of the Alternative Pathway of Complement

  S. Ram, L. A. Lewis & S. Agarwal
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.184838

  Abstract

• Glycoantigens Induce Human Peripheral Tr1 Cell Differentiation with Gut-homing Specialization

  L. S. C. Kreisman & B. A. Cobb
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.206011

  Abstract

• Molecular Stiffness of Selectins

  K. K. Sarangapani, B. T. Marshall, R. P. Mcever & C. Zhu
  Original research paper: Journal of Biological Chemistry 286
  doi:10.1074/jbc.M110.196485

  Abstract

• Effects of Neighboring Glycans on Antibody-Carbohydrate Interaction

  Chi-Hui Liang et al.
  Original research paper: Angewandte Chemie International Edition 50
  doi:10.1002/anie.201003482

  Abstract

• NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic

  Adam W Barb & James H Prestegard
  Original research paper: Nature Chemical Biology 7 147-153 (2011)
  doi:10.1038/nchembio.511

  Abstract