Membrane receptors/ligands
N-linked glycosylation selectively regulates autonomous precursor BCR function
Rudolf Übelhart et al.
Original research paper: Nature Immunology 11
doi:10.1038/ni.1903Ligand identification of carbohydrate-binding proteins employing a biotinylated glycan binding assay and tandem mass spectrometry
Manfred Wuhrer et al.
Original research paper: Analytical Biochemistry 406
doi:10.1016/j.ab.2010.07.008Tumor Cells Secrete Galectin-1 to Enhance Endothelial Cell Activity
V. L. Thijssen et al.
Original research paper: Cancer Research 70
doi:10.1158/0008-5472.CAN-09-4150Endothelial Galectin-1 Binds to Specific Glycans on Nipah Virus Fusion Protein and Inhibits Maturation, Mobility, and Function to Block Syncytia Formation
Omai B. Garner et al.
Original research paper: PLoS Pathogens 6
doi:10.1371/journal.ppat.1000993Rapid Screening of Lectins for Multivalency Effects with a Glycodendrimer Microarray
Núria Parera pera et al.
Original research paper: ChemBioChem 11
doi:10.1002/cbic.201000340Vimentin and desmin possess GlcNAc-binding lectin-like properties on cell surfaces
H. Ise et al.
Original research paper: Glycobiology 20
doi:10.1093/glycob/cwq039Molecular and clinical dissection of CD24 antibody specificity by a comprehensive comparative analysis
Glen Kristiansen et al.
Original research paper: Laboratory Investigation 90
doi:10.1038/labinvest.2010.70Survival Signals of Hepatic Stellate Cells in Liver Regeneration Are Regulated by Glycosylation Changes in Rat Vitronectin, Especially Decreased Sialylation
K. Sano et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M109.077016Tolerogenic Dendritic Cells in the Control of Autoimmune Neuroinflammation: An Emerging Role of Protein-Glycan Interactions
Juan M. Ilarregui & Gabriel A. Rabinovich
Original research paper: Neuroimmunomodulation 17
doi:10.1159/000258712Genetically-Defined Deficiency of Mannose-Binding Lectin Is Associated with Protection after Experimental Stroke in Mice and Outcome in Human Stroke
Alvaro Cervera et al.
Original research paper: PLoS ONE 5
doi:10.1371/journal.pone.0008433Innate immune lectins kill bacteria expressing blood group antigen
Sean R Stowell et al.
Original research paper: Nature Medicine 16 295-301 (2010)
doi:10.1038/nm.2103Regulation of AMPA Receptor Trafficking by O-Glycosylation
Takeshi Kanno et al.
Original research paper: Neurochemical Research 35
doi:10.1007/s11064-010-0135-1Schistosoma mansoni worm glycolipids induce an inflammatory phenotype in human dendritic cells by cooperation of TLR4 and DC-SIGN
Caroline M.W. Van stijn et al.
Original research paper: Molecular Immunology 47
doi:10.1016/j.molimm.2010.01.014In Situ trans Ligands of CD22 Identified by Glycan-Protein Photocross-linking-enabled Proteomics
T. N. C. Ramya et al.
Original research paper: Molecular & Cellular Proteomics 9
doi:10.1074/mcp.M900461-MCP200Lactose Binding to Galectin-1 Modulates Structural Dynamics, Increases Conformational Entropy, and Occurs with Apparent Negative Cooperativity
Irina V. Nesmelova et al.
Original research paper: Journal of Molecular Biology 397
doi:10.1016/j.jmb.2010.02.033Can any lessons be learned from the ambiguous glycan binding of PfEMP1 domains?
Madeleine Dahlbäck, Morten A. Nielsen & Ali Salanti
Original research paper: Trends in Parasitology 26
doi:10.1016/j.pt.2010.02.002A novel lectin with highly potent antiproliferative and HIV-1 reverse transcriptase inhibitory activities from the edible wild mushroom Russula delica
Shuang Zhao et al.
Original research paper: Glycoconjugate Journal 27
doi:10.1007/s10719-009-9274-5Modulation of Cellular Adhesion by Glycoengineering
Laila Dafik, Marc D’alarcao & Krishna Kumar
Original research paper: Journal of Medicinal Chemistry 53
doi:10.1021/jm100374gCore 1-derived O-glycans are essential E-selectin ligands on neutrophils
T. Yago et al.
Original research paper: Proceedings of the National Academy of Sciences 107
doi:10.1073/pnas.1003110107Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes
Jennifer A. Belisle et al.
Original research paper: Molecular Cancer 9
doi:10.1186/1476-4598-9-118Recognition of Galactose-Deficient -Glycans in the Hinge Region of IgA1 by -Acetylgalactosamine-Specific Snail Lectins: A Comparative Binding Study
Michelle M. Gomes et al.
Original research paper: Biochemistry 49
doi:10.1021/bi9019498Human L-selectin preferentially binds synthetic glycosulfopeptides modeled after endoglycan and containing tyrosine sulfate residues and sialyl Lewis x in core 2 O-glycans
A. Leppanen et al.
Original research paper: Glycobiology 20
doi:10.1093/glycob/cwq083Microvirin, a Novel (1,2)-Mannose-specific Lectin Isolated from Microcystis aeruginosa, Has Anti-HIV-1 Activity Comparable with That of Cyanovirin-N but a Much Higher Safety Profile
D. Huskens et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M110.128546GMI-1070, a novel pan-selectin antagonist, reverses acute vascular occlusions in sickle cell mice
J. Chang et al.
Original research paper: Blood 116
doi:10.1182/blood-2009-12-260513Carboxylated N-glycans on RAGE promote S100A12 binding and signaling
Geetha Srikrishna et al.
Original research paper: Journal of Cellular Biochemistry 110
doi:10.1002/jcb.22575Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response
A. I. Markowska, F.-T. Liu & N. Panjwani
Original research paper: Journal of Experimental Medicine 207
doi:10.1084/jem.20090121A Major Fraction of Glycosphingolipids in Model and Cellular Cholesterol-containing Membranes Is Undetectable by Their Binding Proteins
R. Mahfoud et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M110.110189Multiple recognition systems adopting four different glycotopes at the same domain for the Agaricus bisporus agglutinin–glycan interactions
Albert M. Wu et al.
Original research paper: FEBS Letters 584
doi:10.1016/j.febslet.2010.07.021Identification and Characterization of the Carbohydrate Ligands Recognized by Pertussis Toxin via a Glycan Microarray and Surface Plasmon Resonance
Scott H. Millen et al.
Original research paper: Biochemistry 49
doi:10.1021/bi100474zTLR4-Mediated Sensing of Campylobacter jejuni by Dendritic Cells Is Determined by Sialylation
M. L. Kuijf et al.
Original research paper: The Journal of Immunology 185
doi:10.4049/jimmunol.0903014Maintenance of cell surface glycan density by lectin-glycan interactions: A homeostatic and innate immune regulatory mechanism
T. K. Dam & F. C. Brewer
Original research paper: Glycobiology 20
doi:10.1093/glycob/cwq084Multimeric Lactoside “Click Clusters” as Tools to Investigate the Effect of Linker Length in Specific Interactions with Peanut Lectin, Galectin-1, and -3
Sébastien G. Gouin et al.
Original research paper: ChemBioChem 11
doi:10.1002/cbic.201000167Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells
Lubomir Kovar et al.
Original research paper: Tumor Biology 31
doi:10.1007/s13277-010-0019-7Determination of Carbohydrate-Binding Preferences of Human Galectins with Carbohydrate Microarrays
Tim Horlacher et al.
Original research paper: ChemBioChem 11
doi:10.1002/cbic.201000020Glycomimicry: Display of the GM3 sugar epitope on Escherichia coli and Salmonella enterica sv Typhimurium
K. Ilg et al.
Original research paper: Glycobiology 20
doi:10.1093/glycob/cwq091Transmembrane Signaling Proteoglycans
John R. Couchman
Original research paper: Annual Review of Cell and Developmental Biology 26
doi:10.1146/annurev-cellbio-100109-104126Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis
Qicheng Zhao et al.
Original research paper: Molecular Cancer 9
doi:10.1186/1476-4598-9-154Worms to the rescue: Can worm glycans protect from autoimmune diseases?
Loes M. Kuijk & Irma Van die
Original research paper: IUBMB Life
doi:10.1002/iub.304Functional Interaction of Common Allergens and a C-type Lectin Receptor, Dendritic Cell-specific ICAM3-grabbing Non-integrin (DC-SIGN), on Human Dendritic Cells
S.-C. Hsu et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M109.058370A Lectin Isolated from Bananas Is a Potent Inhibitor of HIV Replication
M. D. Swanson, H. C. Winter, I. J. Goldstein & D. M. Markovitz
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M109.034926Heparan sulfate mediates amyloid-beta internalization and cytotoxicity
E. Sandwall et al.
Original research paper: Glycobiology 20
doi:10.1093/glycob/cwp205Lectin-Based Drug Design: Combined Strategy to Identify Lead Compounds using STD NMR Spectroscopy, Solid-Phase Assays and Cell Binding for a Plant Toxin Model
João P. Ribeiro et al.
Original research paper: ChemMedChem 5
doi:10.1002/cmdc.200900476The adhesion mediated by the P-selectin P-selectin glycoprotein ligand-1 (PSGL-1) couple is stronger for shorter PSGL-1 variants
S. Barbaux et al.
Original research paper: Journal of Leukocyte Biology 87
doi:10.1189/jlb.0609408Polysialic acid can mediate membrane interactions by interacting with phospholipids
Teresa Janas, Krzysztof Nowotarski & Tadeusz Janas
Original research paper: Chemistry and Physics of Lipids 163
doi:10.1016/j.chemphyslip.2009.12.003MGL1 promotes adipose tissue inflammation and insulin resistance by regulating 7/4hi monocytes in obesity
D. J. Westcott et al.
Original research paper: Journal of Experimental Medicine 206
doi:10.1084/jem.20091333Fluorinated per-acetylated GalNAc metabolically alters glycan structures on leukocyte PSGL-1 and reduces cell binding to selectins
D. D. Marathe et al.
Original research paper: Blood 115
doi:10.1182/blood-2009-07-231480DC-SIGN and SRCL bind glycans of carcinoembryonic antigen (CEA) and CEA-related cell adhesion molecule 1 (CEACAM1): recombinant human glycan-binding receptors as analytical tools
Alexandra Samsen et al.
Original research paper: European Journal of Cell Biology 89
doi:10.1016/j.ejcb.2009.11.018Dual Specificity of Langerin to Sulfated and Mannosylated Glycans via a Single C-type Carbohydrate Recognition Domain
H. Tateno et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M109.041863Carbohydrate Recognition Properties of Human Ficolins: GLYCAN ARRAY SCREENING REVEALS THE SIALIC ACID BINDING SPECIFICITY OF M-FICOLIN
E. Gout et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M109.065854Mucins in ovarian cancer diagnosis and therapy
Subhash C Chauhan, Deepak Kumar & Meena Jaggi
Original research paper: Journal of Ovarian Research 2
doi:10.1186/1757-2215-2-21Decoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivo
B. H. Duong et al.
Original research paper: Journal of Experimental Medicine 207
doi:10.1084/jem.20091873Association of plasma soluble E-selectin and adiponectin with carotid plaque in patients with systemic lupus erythematosus
Harmony R. Reynolds et al.
Original research paper: Atherosclerosis 210
doi:10.1016/j.atherosclerosis.2009.12.007O-Mannosyl Phosphorylation of Alpha-Dystroglycan Is Required for Laminin Binding
T. Yoshida-moriguchi et al.
Original research paper: Science 327
doi:10.1126/science.1180512Glycosylation Signatures in : Fishing with Lectins
Gianni Vandenborre et al.
Original research paper: Journal of Proteome Research 9
doi:10.1021/pr1001753Duality of the carbohydrate-recognition system of Pseudomonas aeruginosa-II lectin (PA-IIL)
Albert M. Wu, Yu-Ping Gong, Chia-Chen Li & Nechama Gilboa-garber
Original research paper: FEBS Letters 584
doi:10.1016/j.febslet.2010.04.026"Time sweet time": circadian characterization of galectin-1 null mice
Leandro P Casiraghi et al.
Original research paper: Journal of Circadian Rhythms 8
doi:10.1186/1740-3391-8-4Role of Water Molecules in Structure and Energetics of Pseudomonas aeruginosa Lectin I Interacting with Disaccharides
A. Nurisso et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M110.108340Developing High-Affinity Boron-Based Receptors for Cell-Surface Carbohydrates
Todd A. Houston
Original research paper: ChemBioChem 11
doi:10.1002/cbic.201000079HIV-1 and pattern-recognition receptors: a marriage of convenience
Michel J Tremblay
Original research paper: Nature Immunology 11
doi:10.1038/ni0510-363HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells
Sonja I Gringhuis et al.
Original research paper: Nature Immunology 11
doi:10.1038/ni.1858Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes
Santiago F Gonzalez et al.
Original research paper: Nature Immunology 11
doi:10.1038/ni.1856Mucin 21/Epiglycanin Modulates Cell Adhesion
Y. Yi et al.
Original research paper: Journal of Biological Chemistry 285
doi:10.1074/jbc.M109.082875
