Making a brain: Without sugar, NCAM can't
Disruption of a unique type of glycosylation causes pathological brain development and may lead to schizophrenia.
Original research paper: Brain (14 May 2009)
Functional Glycomics Update
Welcome to the June Functional Glycomics Update, your one-stop resource for news, highlights and research on glycobiology.
Featured articles
Specially written Editor's reviews of the hottest new articles
Virus neutralization: Sweet antibodies have more bite
New production systems focusing on the defined glycosylation of antibodies are improving potency and therapeutic potential.
Original research paper: Applied Microbiology and Biotechnology (12 May 2009)
Research Highlights
Synopses of important recent articles
Mucins: Breast milk sours HIV-1 transmission
Breast milk mucins block the dendritic cell receptor DC-SIGN, preventing HIV-1 attachment and thus decreasing the risk of mother-to-child transmission of the virus.
Functional Glycomics Gateway (11 June 2009)
Breast cancer: Metastasis on the brain
Expression of a sialyltransferase gene may allow breast cancer cells to cross the blood-brain barrier and establish metastases.
Nature Reviews Cancer (11 June 2009)
Research library
A growing comprehensive library of all the latest published research
Polysialic acid glycomimetics promote myelination and functional recovery after peripheral nerve injury in mice
Brain
Carbohydrate-binding proteins: Dissecting ligand structures through solvent environment occupancy
The Journal of Physical Chemistry B
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