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Functional Glycomics Update

Welcome to the May Functional Glycomics Update, your one-stop resource for news, highlights and research on glycobiology.

Featured articles

Specially written Editor's reviews of the hottest new articles

Cancer cell MUC1: At the tumor stem

The transmembrane mucin MUC1 occurs in a stem cell subpopulation of the breast cancer cell line MCF-7, and can be targeted in an immunotherapeutic approach by chimeric antigen T-cell receptors.

Cancer Research 68, 2419-2426 (2008)

Angiogenesis: A small candy for the tumor

The fucosylated histo-blood group glycans H2 and Lewis Y are expressed on subgroups of human endothelial cells and promote migration and tumor angiogenesis.

Journal of Cellular Physiology 215, 27-36 (2008)

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Research Highlights

Synopses of important recent articles

PCR glycogene analysis: Medium throughput, higher sensitivity

Quantitative real-time reverse transcriptase-polymerase chain reaction (qRT-PCR) of glycogene expression is now a powerful new tool for glycomic analysis.

Functional Glycomics Gateway (8 May 2008)

Intravenous immunoglobulin (IVIG): Straight from bench to bedside

The anti-inflammatory action of intravenous immunoglobulin (IVIG) is dependent on its alpha2,6-sialylation, and native IVIG can be mimicked by a recombinant, in vitro glycosylated product

Functional Glycomics Gateway (8 May 2008)

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