Welcome to the May Functional Glycomics Update, your one-stop resource for news, highlights and research on glycobiology.
The transmembrane mucin MUC1 occurs in a stem cell subpopulation of the breast cancer cell line MCF-7, and can be targeted in an immunotherapeutic approach by chimeric antigen T-cell receptors.
Cancer Research 68, 2419-2426 (2008)
The fucosylated histo-blood group glycans H2 and Lewis Y are expressed on subgroups of human endothelial cells and promote migration and tumor angiogenesis.
Journal of Cellular Physiology 215, 27-36 (2008)
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Quantitative real-time reverse transcriptase-polymerase chain reaction (qRT-PCR) of glycogene expression is now a powerful new tool for glycomic analysis.
Functional Glycomics Gateway (8 May 2008)
The anti-inflammatory action of intravenous immunoglobulin (IVIG) is dependent on its 
2,6-sialylation, and native IVIG can be mimicked by a recombinant, in vitro glycosylated product
Functional Glycomics Gateway (8 May 2008)
Nature Immunology 9, 513 - 521 (2008)
Proceedings of the National Academy of Sciences 105, 5903 - 5908 (2008)
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