Functional Glycomics Update

Welcome to the August Functional Glycomics Update, your one-stop resource for news, highlights and research on glycobiology.

Featured articles

Specially written Editor's reviews of the hottest new articles

Glycosylation defects: To add sugar, reduce fat

SRD5A3 catalyzes a reduction step in the synthesis of precursors for N-glycosylation, and is mutated in congenital disorders of glycosylation.

Original research paper: Cell (published online 23 July 2010)

Gated ion channels: Held open by glycans?

Glycosylation analysis and homology modeling of a receptor for the inhibitory neurotransmitter GABA reveals regulation by glycosylation.

Original research paper: J. Biol. Chem. (published online 16 July 2010)

Research Highlights

Synopses of important recent articles

Development: Sticky-sweet adhesions

An O-glycosyltransferase controls integrin-mediated cell adhesion during Drosophila development by regulating the secretion of an extracellular matrix protein.

Functional Glycomics (August 2010)

Chemosensation: Tasteless mice prefer sugar

Carbohydrate preferences are determined by glucose oxidation levels rather than by the sweetness or the caloric value of a nutrient.

Nature Reviews Neuroscience (August 2010)

Research library

A growing comprehensive library of all the latest published research

Characteristic increase in nucleocytoplasmic protein glycosylation by O-GlcNAc in 3T3-L1 adipocyte differentiation.

Katsunori Ishihara et al.

Biochemical and Biophysical Research Communications