Phase II: Reaching out to the Participating Investigators
One of the goals of the Consortium for Functional
Glycomics is to generate resources for the use of investigators in studying
the complex biology that governs the interactions of glycan-binding proteins
and their ligands in mediating cell communication.
The following scientific cores need your help and feedback:
Major objectives
Expand existing mammalian and pathogen glycan arrays
- Terminal structure motifs
- Branched N- and O-linked glycans
Expand Reagent bank (Glycans, Antibodies, Glycosyltransferases)
Needed from Participating Investigators
Targets for expansion of existing mammalian and pathogen glycan arrays
- Terminal glycan motifs not currently on the glycan array
- Terminal motifs for elaboration on N-linked and O-linked glycan cores
Suggestions for monoclonal antibodies for reagent bank
Synthetic or pure natural glycans for elaboration on the CFG mammalian and pathogen glycan arrays (supplied as reducing sugars, or with amine, azide, or amino acid/peptide, linkers)
To view the list of mammalian compounds for future synthesis proposed by Participating Investigators as of today, click here.
Send your suggestions/feedback to either core directors Nahid Razi and David Smith
or core coordinators James C. Paulson and Richard D. Cummings
Other suggestions:
- Synthesis of compounds for mammalian and pathogen glycan arrays library, N-linked and O-linked glycan standards synthesis by Glycan Array Synthesis (Core D)
- Pathogen Glycans for the pathogen glycan microarray (Core H)
- KO targets for Mouse Transgenic (Core F)
- Mentors for KO mice being phenotyped by (Core G)
- Pure human and murine cell populations for glycomics profiling (Core C)
- Gene expression analysis (Core E)
- Annotation of glycan binding protein molecule pages for the CFG database (Core B)
Last Updated Saturday, 23-Aug-2008 02:14:23 EDT. Please contact us
with comments/questions.
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