Functional Glycomics homepage

REAGENT BANK
CARBOHYDRATE COMPOUNDS,
GLYCAN-BINDING PROTEINS & ANTIBODIES

The Glycan Array Synthesis Core (D) produces glycan-specific antibodies for the CFG Reagent Bank. The antibodies listed below are available for investigators to identify and/or purify glycoconjugates, inhibit protein-glycan interactions, define the glycosylation status of cells, perform histochemical staining, assay enzymes, sort cells, and more. These studies help achieve the CFG's overall goal to "define paradigms by which protein-carbohydrate interactions mediate cell communication" by meeting the specific aims to:
  • Define the specificity and affinity for carbohydrate ligands
  • Establish the cell types involved in communication
  • Identify the ligand(s) that mediate glycan-binding protein (GBP) binding
  • Determine how GBP-ligand interactions mediate cell communication


Antibodies to Siglecs
Antibody Quantity
Sheep anti-mCD33 10 micrograms/100 microliters/vial
Sheep anti-mSiglec E 10 micrograms/100 microliters/vial
Sheep anti-mSiglec E-FITC 5 micrograms/50 microliters/vial
Sheep anti-mSiglec F 10 micrograms/100 microliters/vial
Sheep pre-immune IgG (control) 10 micrograms/100 microliters/vial


Anti-glycan IgY polyclonal antibodies
Antibody Quantity Batch No.
Anti blood group A, IgY 0.25 milliliters/vial (9.0 mg/ml) Chicken # 264
Anti Globo H, IgY 0.25 milliliters/vial (4.8 mg/ml) Chicken # 272
Anti Sialyl Lewisx , IgY 0.25 milliliters/vial (8.75 mg/ml) Chicken # 270
Anti Tri- LacNAc,IgY 0.25 milliliters/vial (8.9 mg/ml) Chicken # 265
Pre-immune IgY 0.25 milliliters/vial (7.4 mg/ml) Chicken # 266


Anti-glycan Monoclonal antibodies
Antibody Quantity
2C9, Blood group A, IgG1 5 milliliters hybridoma supernatant
BE2, Blood group H-type2, IgM 1 milliliters hybridoma supernatant
HH6, Pan A- group A (all variants), IgG3 1 milliliters hybridoma supernatant
HH8, T-antigen, IgM 1 milliliters hybridoma supernatant
SH1, Lewis X, IgG3 5 milliliters hybridoma supernatant

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Last Updated Tuesday, 09-Mar-2010 17:48:34 EST. Please contact us with comments/questions.