Protein: Sheep anti-mSiglec E

Type: IgG

Buffer: PBS + 0.1% BSA + 10 mM azide

Purity: No detectable cross-reactivity at 5 micrograms/ml was seen.

Storage temperature: 4ºC

Activity: Immunoprecipitation: 2 micrograms/ml. It is recommended that the antibody be titered for optimization before use.

Pre-immune IgG: Not available.

Expression: Expressed on cells of the innate immune system (e.g. neutrophils, macrophages, mature NK cell etc). Absent from NKT cells and T cells.

References:

Zhang J, Biedermann B, Nitschke L, et al. The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. Eur J Immunol. 2004;34:1175-1184.