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MOUSE LINES

Original publication name: b1,4GalT1

Colony code name: BT

Gene symbol: B4galt1

Gene name(s): b-1,4 GalT1

Protein name: UDP-Gal:bGlcNAc b-1,4 galactosyltransferase, polypeptide 1; b-1,4 galactosyltransferase I

Chromosome: 4

Reported function: Transfer of galactose to terminal N-acetylglucosamine of complex type N-glycans in Golgi apparatus

Genomic DNA source: 129/Sv

Mutation type: Neo replacement of exon 1

ES cell line: AB1

Current genetic background: C57Bl/6 (85 percent as determined by whole genome scan, plus one more generation backcrossed at Core F)

Breeding phenotype: Total gene ablation; homozygous neonatal lethal, most neonates die

Name of contributing investigator: Shur B.

Name of institution: Emory University School of Medicine, Atlanta, Georgia

Primary reference: Lu Q, et al. Developmental Biology. 1997;181(2):257-267. [PubMed]





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