Glycan Array Experiment: primscreen_5275
Glycan Array ID
:
primscreen_5275
Sample Name
:
DC-SIGN
Sample Category
:
C Type Lectins
Investigator:
:
Daniel Mitchell
Download Data:
Sample Information:
Name
:
DC-SIGN
Complete Name
:
CD209 antigen, Dendritic cell-specific ICAM-3-grabbing nonintegrin 1, DC-SIGN1
Family
:
C-Type Lectin
Sub Family
:
2-Type 2 Receptor
Gene Symbol
:
CD209
Synonyms
:
CD209 antigen
Species Common Name:
:
Human
Species Scientific Name
:
Homo sapiens
Estimated Purity
:
Information not entered/not applicable.
Mutation/Chimera
:
Information not entered/not applicable.
Entry Date [yyyy-mm-dd]
:
2004-12-09
Status
:
Public
Primary Sequence
:
MSDSKEPRLQQLGLLEEEQLRGLGFRQTRGYKSLAGCLGHGPLVLQLLSFTLLAGLLVQVSKVPSSISQEQSRQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTWLKAAVGELPEKSKMQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTRLKAAVGELPEKSKQQEIYQELTQLKAAVERLCHPCPWEWTFFQGNCYFMSNSQRNWHDSITACKEVGAQLVVIKSAEEQNFLQLQSSRSNRFTWMGLSDLNQEGTWQWVDGSPLLPSFKQYWNRGEPNNVGEEDCAEFSGNGWNDDKCNLAKFWICKKSAASCSRDEEQFLSPAPATPNPPPA
Comments
:
Information not entered/not applicable.
Known Sites of Expression
:
Pooled human melanocyte, fetal heart, and pregnant uterus ;RPE and Choroid ;lens
External References :
Genbank
:
AF290886
Pdb
:
1K9I
Pdb
:
1SL4
Pdb
:
1SL5
Omim_Parse_Links
:
604672
Swissprot
:
Q9NNX6
Omim
:
604672
Pdb
:
2B6B
Experiment Information:
Status:
:
Public
Title/Project Description:
:
The purpose of this study is to identify and functionally characterize novel humoral and cellular glycan-binding proteins and specific glycan distributions within mammalian species, including tetrameric human DC-SIGN and DC-SIGNR.
Associated Resource Requests:
:
cfg_rRequest_2569
Glycan Array Version:
:
PA_v5
Protocol Used:
:
Protocol Tertiary step
Replicate Number:
:
1
Result Nature:
:
Data
Protein/Sample Concentration:
:
200 μg/ml
Experiment Date [yyyy-mm-dd]:
:
2012-03-29
Supplying Investigator
:
Daniel Mitchell
Specific Assay Information
:
Sample was diluted and detected with anti-DC-Sign/R antibody (sent by PI, used at 2ug/ml in binding buffer) followed by Alexa488-labeled anti-mouse IgG.
Annotation
:
Human DC-Sign-tetramer
Protein Sample Analyzed
:
DC-SIGN