Request ID: cfg_rRequest_1882
Status
:
Approved
Project Description
:
Continued studies of RR#1511, RR#1611, RR#1671, RR#1797 - to develop a binding profile for these additional hemagglutinin (HA) proteins derived from different serotypes of avian influenza A viruses.
CFG Member
:
Member
Requester First Name
:
Xander
Requester Last Name
:
de Haan
Head of Lab First Name
:
Peter
Head of Lab Last Name
:
Rottier
Assigned First Name
:
Peter P.J.M
Assigned Last Name
:
Rottier
Requester Email
:
c.a.m.dehaan@uu.nl
Requester Interest
:
This laboratory is focusing on virus-host interactions at the cellular and molecular level, with particular focus on influenza- and nidoviruses.
Request Date [yyyy-mm-dd]
:
2009-12-16
Institution
:
Virology Division, Utrecht university
Shipping Address
:
Virology Division
Yalelaan 1
3584 CL Utrecht
The Netherlands
+31-30-2534195
Comments
:
Information not entered/not applicable.
CFG Core
:
H
Resource Type
:
Glycoarray
Amount Requested
:
Information not entered/not applicable.
Date that your RNA/GBP samples will be sent to the core [yyyy-mm-dd]
:
2010-01-15
Experiment to be conducted
:
We would like to extent our ongoing analysis of influenza A HA-receptor interactions (see requests 1611, 1671 and 1797). We would like to assays a few HAs derived from mammals and avian species (8 samples)that have not been tested before. In addition we would like to retest two HAs with the improved protocol.
Within Scope of Consortium
:
Y
If yes, indicate the person responsible for inputing data into core B
:
xander de Haan
GBP being Addressed
:
the recombinant trimeric HAs will be detected as described previously. (using antibodies against the purification tag and FITC labeled secondary antibodies).
Specifc aims being addressed
:
Define the specificity and affinity for carbohydrate ligands.